NEUROBEHAVIORAL BASES OF EMOTION REGULATION AND DYSREGULATION IN ADOLESCENCE

青春期情绪调节和失调的神经行为基础

• 批准号: 8358228
• 负责人: Ned H Kalin
• 金额: $ 10.56万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8358228
• 关键词: Adolescence; Adolescent; Amygdaloid structure; Animals; Anxiety; Behavioral; Data; Development; Funding; Grant; Image; Information Services; Library Services; Mental Depression; Molecular; National Center for Research Resources; Pathology; Primates; Principal Investigator; Psychopathology; Research; Research Infrastructure; Resources; Risk; Services; Source; Stress; United States National Institutes of Health; Wisconsin; base; cost; emotion regulation; neural circuit; neurobehavioral

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Objective: To understand the neural circuits and molecular mechanisms underlying the adolescent vulnerability to develop stress-induced psychopathology. The full title of this project is, "The Neurobehavioral Bases of Emotion Regulation and Dysregulation in Adolescence: Developmental Mechanisms Underlying the Risk to Develop Anxiety and Depression." Using microPET images, we defined groups based on high, middle and low amygdala reactivity during a behavioral challenge. These subjects have been further characterized behaviorally and physiologically both prior to and following relocation stress. These data will be used to define the parameters that engender vulnerability to psychopathology. This research used WNPRC Animal Services, Pathology, Operational Services, and Library & Information Services. PUBLICATIONS: None.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 目的：了解依据的神经回路和分子机制 培养压力引起的心理病理学的青少年脆弱性。 该项目的全部标题是：“青春期情绪调节和失调的神经行为基础：发展焦虑和抑郁风险的发展机制”。 使用MicroPET图像，我们根据行为挑战期间根据高，中和低杏仁核反应性定义了组。这些受试者在搬迁应力之前和之后在行为和生理上都在行为和生理上得到了进一步的特征。这些数据将用于定义引起精神病理脆弱性的参数。 这项研究使用了WNPRC动物服务，病理学，操作服务以及图书馆和信息服务。 出版物： 没有任何。