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中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金, 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 目的:了解灵长类动物情绪表达的神经系统。 基线的大脑代谢、行为和生理测量的特点是为消融膝下区25做准备,这是一个与抑郁症有关的区域。这些研究的发现将与人类高度相关,解决杏仁核-眼眶额叶相互作用在调节正常情绪和精神病理中的作用。 这项工作使用了WNPRC动物服务、病理学、操作服务以及图书馆和信息服务。 一份出版物正在出版中。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: To understand the neural system underlying the expression of emotion in primates. Baseline brain metabolism, behavior, and physiological measures were characterized in preparation for ablation of subgenual Area 25, an area that has been implicated in depression. The findings from these studies will be highly relevant to humans, addressing the role of amygdala-orbitofrontal interactions in mediating normal emotion and psychopathology. This work used WNPRC Animal Services, Pathology, Operational services, and Library and Information services. A publication is in press.
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会议论文
Brain Mechanisms Mediating Genetic Risk for Anxiety and Depression
  • 批准号:
    10522657
  • 项目类别:
  • 资助金额:
    $77.75万
  • 财政年份:
    2023
  • 负责人:
    Ned H Kalin
  • 依托单位:
A translational approach for identifying factors and mechanisms underlying pathological anxiety in preadolescent girls
  • 批准号:
    10637744
  • 项目类别:
  • 资助金额:
    $73.0万
  • 财政年份:
    2023
  • 负责人:
    Ned H Kalin
  • 依托单位:
Extreme anxiety in females: The role of the bed nucleus of the stria terminalis (BST) during the transition to adolescence in human and nonhuman primates
  • 批准号:
    9111065
  • 项目类别:
  • 资助金额:
    $68.38万
  • 财政年份:
    2015
  • 负责人:
    Ned H Kalin
  • 依托单位:
Brain Mechanisms Underlying Childhood Generalized Anxiety Disorder
  • 批准号:
    8460804
  • 项目类别:
  • 资助金额:
    $21.67万
  • 财政年份:
    2012
  • 负责人:
    Ned H Kalin
  • 依托单位:
海外基金