BRAIN MECHANISMS MEDIATING GENETIC RISK FACTORS FOR ANXIETY AND DEPRESSION
BRAIN MECHANISMS MEDIATING GENETIC RISK FACTORS FOR ANXIETY AND DEPRESSION
批准号:
8358229
负责人:
Ned H Kalin
金额:
$33.39万
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-05-01 至 2012-04-30
关键词:
AnimalsAnxietyBase of the BrainBehavioralBrainCandidate Disease GeneDevelopmentEmotionsFoxesFundingGeneticGrantHeritabilityHippocampus (Brain)Information ServicesLibrary ServicesMediatingMental DepressionNational Center for Research ResourcesNaturePrimatesPrincipal InvestigatorResearchResearch InfrastructureResourcesServicesSourceTemperamentUnited States National Institutes of HealthWisconsinWorkbasecostgenetic risk factorresponse
中文摘要
这个子项目是利用这些资源的众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the resources
provided by a Center grant funded by NIH/NCRR. Primary support for the subproject
and the subproject's principal investigator may have been provided by other sources,
including other NIH sources. The Total Cost listed for the subproject likely
represents the estimated amount of Center infrastructure utilized by the subproject,
not direct funding provided by the NCRR grant to the subproject or subproject staff.
Objective: To investigate the genetic basis of brain development and mechanisms underlying
anxiety and depression.
We are defining candidate genes that are likely to influence the brain's response to a behavioral challenge in order to understand the heritability of the neurocircuitry of emotion. These studies will further our understanding of the genetic bases of vulnerability to anxiety and depression.
This work used WNPRC Animal Services, Operational Services, and Library & Information Services.
PUBLICATION:
Oler JA, Fox AS, Shelton SE, Rogers J, Dyer TD, Davidson RJ, Shelledy W, Oakes TR,
Blangero J Kalin NH. (2010) Amygdalar and hippocampal substrates of anxious
temperament differ in their heritability. Nature 466(7308):864-8. PMID 20703306. PMCID PMC2998538.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Brain Mechanisms Mediating Genetic Risk for Anxiety and Depression
-
批准号:10522657
-
项目类别:
-
资助金额:$77.75万
-
财政年份:2023
-
负责人:Ned H Kalin
-
依托单位:
A translational approach for identifying factors and mechanisms underlying pathological anxiety in preadolescent girls
-
批准号:10637744
-
项目类别:
-
资助金额:$73.0万
-
财政年份:2023
-
负责人:Ned H Kalin
-
依托单位:
Extreme anxiety in females: The role of the bed nucleus of the stria terminalis (BST) during the transition to adolescence in human and nonhuman primates
-
批准号:9111065
-
项目类别:
-
资助金额:$68.38万
-
财政年份:2015
-
负责人:Ned H Kalin
-
依托单位:
Brain Mechanisms Underlying Childhood Generalized Anxiety Disorder
-
批准号:8460804
-
项目类别:
-
资助金额:$21.67万
-
财政年份:2012
-
负责人:Ned H Kalin
-
依托单位:
Brain Mechanisms Underlying Childhood Generalized Anxiety Disorder
-
批准号:8303688
-
项目类别:
-
资助金额:$18.81万
-
财政年份:2012
-
负责人:Ned H Kalin
-
依托单位:
EMOTIONAL PROCESSING
-
批准号:8358191
-
项目类别:
-
资助金额:$15.64万
-
财政年份:2011
-
负责人:Ned H Kalin
-
依托单位:
NEUROBEHAVIORAL BASES OF EMOTION REGULATION AND DYSREGULATION IN ADOLESCENCE
-
批准号:8358228
-
项目类别:
-
资助金额:$10.56万
-
财政年份:2011
-
负责人:Ned H Kalin
-
依托单位:
Combining mouse and monkey models to understand human risk for psychopathology
-
批准号:8047063
-
项目类别:
-
资助金额:$18.56万
-
财政年份:2010
-
负责人:Ned H Kalin
-
依托单位:
EMOTIONAL PROCESSING
-
批准号:8173058
-
项目类别:
-
资助金额:$3.1万
-
财政年份:2010
-
负责人:Ned H Kalin
-
依托单位:
BRAIN MECHANISMS MEDIATING GENETIC RISK FACTORS FOR ANXIETY AND DEPRESSION
-
批准号:8173139
-
项目类别:
-
资助金额:$3.1万
-
财政年份:2010
-
负责人:Ned H Kalin
-
依托单位:
Combining mouse and monkey models to understand human risk for psychopathology
-
批准号:8197383
-
项目类别:
-
资助金额:$22.28万
-
财政年份:2010
-
负责人:Ned H Kalin
-
依托单位:
NEUROBEHAVIORAL BASES OF EMOTION REGULATION AND DYSREGULATION IN ADOLESCENCE
-
批准号:8173138
-
项目类别:
-
资助金额:$3.1万
-
财政年份:2010
-
负责人:Ned H Kalin
-
依托单位:
DEVELOPMENTAL MECHANISMS UNDERLYING THE RISK TO DEVELOP ANXIETY AND DEPRESSION
-
批准号:8076860
-
项目类别:
-
资助金额:$35.6万
-
财政年份:2010
-
负责人:Ned H Kalin
-
依托单位:
EMOTIONAL PROCESSING
-
批准号:7958723
-
项目类别:
-
资助金额:$4.98万
-
财政年份:2009
-
负责人:Ned H Kalin
-
依托单位:
NEUROBEHAVIORAL BASES OF EMOTION REGULATION AND DYSREGULATION IN ADOLESCENCE
-
批准号:7958819
-
项目类别:
-
资助金额:$4.68万
-
财政年份:2009
-
负责人:Ned H Kalin
-
依托单位:
AFFECTIVE STYLE: NEURAL AND BEHAVIORAL SUBSTRATES
-
批准号:7958752
-
项目类别:
-
资助金额:$4.68万
-
财政年份:2009
-
负责人:Ned H Kalin
-
依托单位:
BRAIN MECHANISMS MEDIATING GENETIC RISK FACTORS FOR ANXIETY AND DEPRESSION
-
批准号:7958820
-
项目类别:
-
资助金额:$4.68万
-
财政年份:2009
-
负责人:Ned H Kalin
-
依托单位:
Brain Mechanisms Mediating Genetic Risk For Anxiety And Depression
-
批准号:10394790
-
项目类别:
-
资助金额:$71.45万
-
财政年份:2008
-
负责人:Ned H Kalin
-
依托单位:
Brain Mechanisms Mediating Genetic Risk For Anxiety and Depression
-
批准号:9044823
-
项目类别:
-
资助金额:$66.06万
-
财政年份:2008
-
负责人:Ned H Kalin
-
依托单位:
Brain Mechanisms Mediating Genetic Risk Factors for Anxiety and Depression
-
批准号:8098839
-
项目类别:
-
资助金额:$112.58万
-
财政年份:2008
-
负责人:Ned H Kalin
-
依托单位:
海外基金