Northern Manhattan Initiative for Minority Involvement in Clinical Trials

北曼哈顿少数民族参与临床试验倡议

基本信息

批准号：
8278816
负责人：
BERNADETTE Marie BODEN-ALBALA
金额：
$ 78.63万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-09-22 至 2012-03-17
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8278816
关键词：
ARHGEF5 gene Academic Medical Centers Address Attitude Behavioral Bioethics Bioinformatics Biological Clinic Clinical Clinical Research Clinical Trials Collaborations Collection Communities Community Health Community Hospitals Consensus Country Educational Curriculum Enrollment Family Goals Guidelines Hispanics Hospitals Human Resources Individual Institutes Institution Instruction Latino Lead Literacy Programs Literature Minority Minority Groups New York Not Hispanic or Latino Observational Study Participant Perception Population Positioning Attribute Practice Guidelines Presbyterian Church Procedures Randomized Clinical Trials Recruitment Activity Relative (related person)Research Research Infrastructure Research Personnel Resources Sampling Specimen Surveys Testing Training Translational Research U-Series Cooperative Agreements Universities Work community planning comparative effectiveness effectiveness research experience health disparity health literacy improved innovation instrument literacy member minority health multidisciplinary programs response success tool

项目摘要

DESCRIPTION (provided by applicant): Poor recruitment and retention of minority populations in clinical research, and clinical trials in particular, continues to be a significant barrier in te reduction of health disparities. Although we have been successful we realize that there are few best-practice guidelines which have systematically outlined successful strategies to promote and sustain successful recruitment and retention of minority populations. This application was prepared in response to RFA-MD-11-005. NIMHD Resource-Related Minority Health and Health Disparities Research (U24). This proposal will specifically address focus "(a) Bioethics Research Infrastructure Initiative". Our goal is to integrate and expand existing resources to refine and support a comprehensive multidisciplinary program to enhance clinical trial recruitment and retention of minority individuals. This program will be lead by a partnership between the Community Engagement Core Resource ofthe Irving Institute for Clinical Translational Research (IICTR; UL1 RR024156) and the Northern Manhattan Center of Excellence in Minority Health and Health Disparities (NOCEMHD; P60 MD000206). NOCEMHD also includes the Northern Manhattan Center of Excellence for Comparative Effectiveness Research (CER) to Eliminate Disparities (NOCERED; P60 MD000206PI-08S1). The CECR, NOCEMHD, and NOCERED currently conduct and support recruitment of minorities for clinical trials, and are central resources for minority recruitment in research in Northern Manhattan. We will call this proposed program the Northern Manhattan Initiative for Minority involvement in Clinical Trials (NIMICT). The specific aims (SA) of NIMICT are: 1) Develop, pilot, and evaluate a toolkit of "Best Practices" (instruments and procedures) for the conduct of successful recruitment and retention of racial and ethnic minorities in clinical trials; 2) Expand and refine innovative recruitment strategies recently implemented at CUMC for general research for use in minority recruitment and retention in clinical trials, including a community health worker program and a health literacy program; 3) Building on the experience from SAs 1,2 and in collaboration with relevant stakeholders, NIMHD, and other national centers, disseminate the experience of our initiative and seek consensus to develop local and national guidelines for recruitment and retention of minorities in clinical trials. As part of the cooperative agreement, we expect significant collaboration with NIMHD and with other programs in the country with a similar focus. PUBLIC HEALTH RELEVANCE: RELEVANCE (See instructions): Poor recruitment and retention of minority populations in clinical research and clinical trials in particular continues o be significant barrier in the reduction of health disparities. Our goal is to develop and test tool, procedures and guidelines to improve minority recruitment and retention in clinical trials in collaboration with NIMHD and other national programs to be implemented locally and nationally.

描述（由申请人提供）：在临床研究中，尤其是临床试验中少数群体的招募和保留不良，仍然是降低健康差异的重大障碍。尽管我们已经取得了成功，但我们意识到，最佳实践指南几乎没有系统地概述成功的策略，以促进和维持成功的少数群体招募和保留。该应用是根据RFA-MD-11-005响应的。 NIMHD与资源有关的少数民族健康与健康差异研究（U24）。该建议将特别针对重点“（a）生物伦理学研究基础设施计划”。我们的目标是整合和扩展现有资源，以完善和支持一项全面的多学科计划，以增强少数人的临床试验招聘和保留。该计划将取决于欧文临床转化研究所（IICTR; UL1 RR024156）的社区参与核心资源与曼哈顿北部少数民族健康与健康差异卓越中心（Nocemhd; Nocemhd; p60 MD000206）之间的合作伙伴关系。 Nocemhd还包括曼哈顿北部的比较有效性研究卓越中心（CER），以消除差异（Nocered; p60 MD000206PI-08S1）。 CECR，NOCEMHD和NOCERED当前进行和支持少数群体进行临床试验，并且是曼哈顿北部研究少数族裔招募的核心资源。我们将这项拟议的计划称为北部曼哈顿北部少数群体参与临床试验（NIMICT）的计划。 nimict的具体目的（SA）是：1）开发，试点和评估“最佳实践”工具包（工具和程序），以成功地招募和保留种族和少数民族在临床试验中； 2）扩展和完善最近在CUMC实施了创新招聘策略，用于一般研究，用于用于少数族裔招聘和保留临床试验，包括社区卫生工作者计划和健康素养计划； 3）基于SAS 1,2的经验，并与相关的利益相关者NIMHD和其他国家中心合作，传播了我们倡议的经验，并寻求共识，以制定本地和国家培训少数民族在临床试验中的招募和保留率。作为合作协议的一部分，我们期望与NIMHD以及该国其他计划的重大合作。公共卫生相关性：相关性（请参阅说明）：尤其是在临床研究和临床试验中，少数群体招募和保留少数人的招募和保留率不佳，尤其是在降低健康差异方面的重大障碍。我们的目标是开发和测试工具，程序和准则，以与NIMHD和其他国家计划合作，在临床试验中改善少数族裔招募和保留率，并将在本地和全国实施。