UCLA-UCI Center for Eliminating Cardio-Metabolic Disparities in Multi-Ethnic Populations

加州大学洛杉矶分校-加州大学尔湾分校消除多种族人群心脏代谢差异中心

• 批准号: 10659234
• 负责人: BERNADETTE Marie BODEN-ALBALA
• 金额: $ 73.2万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-24 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10659234
• 关键词: Achievement; Address; Adult; Advocacy; Affect; American Heart Association; Area; Behavior Therapy; Behavioral; Biological Process; Black Populations; Blood Pressure; Blood Pressure Monitors; Blood Vessels; California; Cardiovascular Diseases; Cause of Death; Cessation of life; Child; Color; Communication; Communities; Community Health; Community Health Aides; Cost Savings; County; Data; Development; Disparity; Economics; Education; Effectiveness; Equity; Ethnic Population; Event; Family; Growth; Health; Heart Diseases; Household; Hypertension; Individual; Intervention; Latino; Latino Population; Learning; Life; Life Style; Link; Measures; Modeling; Multilingualism; Myocardial Infarction; Oranges; Participant; Patients; Physical environment; Population; Population Heterogeneity; Prevention; Prevention strategy; Primary Prevention; Provider; Psychological reinforcement; Race; Randomized, Controlled Trials; Research; Risk; Risk Factors; Risk Reduction; Self Efficacy; Shapes; Social Network; Social Processes; Stroke; Testing; Translating; Underserved Population; Vascular Diseases; Vietnamese; Work; Youth; behavior change; blood pressure reduction; cardiometabolism; cardiovascular disorder prevention; cardiovascular disorder risk; cardiovascular health; cardiovascular risk factor; clinically significant; community based participatory research; community engagement; disability; disparity gap; efficacy evaluation; efficacy testing; empowerment; ethnic disparity; family structure; health equity; heart disease risk; hypertension prevention; improved; mortality; multi-ethnic; novel; prevent; prevention effectiveness; programs; provider communication; racial disparity; reinforced behavior; residential segregation; risk perception; skills; social; social capital; social determinants; social movement; social structure; socioeconomic disparity; socioeconomics; support network; technological innovation; treatment adherence; treatment as usual; web portal; young adult

PROJECT SUMMARY Stroke and cardiovascular disease account for 1 in 4 deaths among Latinos in the U.S, and heart disease is the second leading cause of death overall. Vietnamese populations in southern CA have persistently high rates of hypertension linked to elevated rates of stroke. Hypertension disproportionately affects communities of color who are often concentrated residentially due to race-based residential segregation. Disinvestment in the social, economic, and physical environment in communities of color enhances barriers to cardiovascular disease risk prevention and management. These disparities, along with the continued growth of diverse populations in southern California and across the U.S., highlight the need for novel, community-level interventions to prevent hypertension. Primordial prevention of hypertension is critical in moving forward in terms of the achievement of ideal cardiovascular health cardiovascular health for all. There is growing evidence that integrating families and social networks into behavioral interventions may enhance the efficacy, effectiveness and sustainability of vascular risk reduction. The Skills-based Educational strategies to Reduce Vascular Events in Orange County (SERVE OC) intervention is a culturally-tailored, skills-based educational program set within a supportive family structure and utilizing a community health worker model. Our hypothesis is that this approach will optimize successful long-term behavioral change for prevention of hypertension among adults and children in Vietnamese and Latino households in Orange County, CA. This hypothesis is supported by significant formative research, including our original Discharge Educational Strategies for Reduction of Vascular Events (DESERVE) intervention randomized control trial. DESERVE shifted the paradigm for vascular risk reduction strategies by translating information to skills-based actions resulting in a clinically significant reduction in systolic blood pressure overall and a statistically significant reduction in systolic blood pressure among Latinos. DESERVE also found that blood pressure reduction was enhanced among those with stronger support networks. This proposal seeks to test with SERVE OC whether we can optimize, through adaptation, the DESERVE intervention model for blood pressure reduction by using family networks as a platform to deliver primary prevention of hypertension.

项目摘要 中风和心血管疾病占美国拉丁裔四分之一的死亡，心脏病是 总体死亡的第二大原因。越南南部的越南人口持续很高 高血压与中风率升高有关。高血压不成比例地影响有色人种 由于基于种族的居民种族隔离，他们经常被居住。在社会上投资 有色社区的经济和物理环境增强了心血管疾病风险的障碍 预防和管理。这些差异，以及不同人口的持续增长 南加州和整个美国，强调了需要进行新颖的社区级干预措施以防止 高血压。预防高血压的原始预防对于取得成就至关重要 所有人的理想心血管健康心血管健康。越来越多的证据表明将家庭整合到 社交网络进入行为干预措施可能会增强 降低血管风险。基于技能的教育策略，以减少奥兰治县的血管事件 （服务OC）干预是一项基于文化的，基于技能的教育计划 家庭结构并利用社区卫生工作者模式。我们的假设是这种方法将 优化成功的长期行为改变，以预防成人和儿童的高血压 加利福尼亚州奥兰治县的越南和拉丁裔家庭该假设得到了重要的支持 形成性研究，包括我们最初的出院教育策略，用于减少血管事件 （应得的）干预随机对照试验。值得改变范式以减少血管风险 通过将信息转换为基于技能的行动，从而临床上显着减少的策略 总体上的收缩压和拉丁美洲裔收缩压的统计学显着降低。 应得的还发现，在支持较强的人群中，血压降压得到了增强 网络。该建议旨在通过适应来优化OC测试OC 应使用家庭网络作为交付的平台，以减少血压的干预模型 一级预防高血压。