National Initiative for Minority Involvement in Neurological Clinical Trials

临床研究，特别是临床试验中少数群体的招募和保留情况不佳， 仍然是减少健康差距的一个重大障碍。虽然我们已经成功地 我们认识到，很少有最佳实践指南系统地概述了成功的 促进和维持成功征聘和留住少数民族人口的战略。这 根据RFA-MD-11-005编写申请。NIMHD与资源有关的少数民族健康和 健康差异研究（U24）。该提案将具体涉及“（a）生物伦理学研究 基础设施倡议”。我们的目标是整合和扩大现有资源，以完善和支持 全面的多学科计划，以加强临床试验招募和保留少数民族 个体该计划将由社区参与核心资源 欧文临床转化研究所（IICTR; UL 1 RR 024156）和北方 少数民族健康和健康差异卓越曼哈顿中心（NOCEMHD; P60 MD 000206）。 NOCEMHD还包括北方曼哈顿比较有效卓越中心 消除差异的研究（CER）（NOCERED; P60 MD 000206 PI-08 S1）。CECR。NOCEMHD， 和NOCERED目前正在进行和支持招募少数民族进行临床试验， 为北方曼哈顿的研究招募少数族裔提供资源。我们将把这个计划称为 北方曼哈顿少数民族参与临床试验倡议（NIMICT）。具体目标（SA） （1）开发、试行和评估一套“最佳做法”（工具和程序）， 在临床试验中成功招募和保留少数种族和族裔; 2）扩大和 改进最近在哥伦比亚大学实施的创新招聘战略，用于一般研究， 少数民族招募和保留临床试验，包括社区卫生工作者计划和健康 扫盲方案; 3）在战略行动方案1、2的经验基础上，与相关利益攸关方合作， NIMHD和其他国家中心传播我们倡议的经验并寻求共识， 为临床试验中招募和保留少数群体制定地方和国家指导方针。的一部分 合作协议，我们希望与NIMHD和其他计划的重大合作， 有着相似的关注点。

Poor recruitment and retention of minority populations in clinical research, and clinical trials in particular, continues to be a significant barrier in the reduction of health disparities. Although we have been successful we realize that there are few best-practice guidelines which have systematically outlined successful strategies to promote and sustain successful recruitment and retention of minority populations. This application was prepared in response to RFA-MD-11-005. NIMHD Resource-Related Minority Health and Health Disparities Research (U24). This proposal will specifically address focus "(a) Bioethics Research Infrastructure Initiative". Our goal is to integrate and expand existing resources to refine and support a comprehensive multidisciplinary program to enhance clinical trial recruitment and retention of minority individuals. This program will be lead by a partnership between the Community Engagement Core Resource ofthe Irving Institute for Clinical Translational Research (IICTR; UL1 RR024156) and the Northern Manhattan Center of Excellence in Minority Health and Health Disparities (NOCEMHD; P60 MD000206). NOCEMHD also includes the Northern Manhattan Center of Excellence for Comparative Effectiveness Research (CER) to Eliminate Disparities (NOCERED; P60 MD000206PI-08S1). The CECR. NOCEMHD, and NOCERED currently conduct and support recruitment of minorities for clinical trials, and are central resources for minority recruitment in research in Northern Manhattan. We will call this proposed program the Northern Manhattan Initiative for Minority involvement in Clinical Trials (NIMICT). The specific aims (SA) of NIMICT are: 1) Develop, pilot, and evaluate a toolkit of "Best Practices" (instruments and procedures) for the conduct of successful recruitment and retention of racial and ethnic minorities in clinical trials; 2) Expand and refine innovative recruitment strategies recently implemented at CUMC for general research for use in minority recruitment and retention in clinical trials, including a community health worker program and a health literacy program; 3) Building on the experience from SAs 1,2 and in collaboration with relevant stakeholders, NIMHD, and other national centers, disseminate the experience of our initiative and seek consensus to develop local and national guidelines for recruitment and retention of minorities in clinical trials. As part of the cooperative agreement, we expect significant collaboration with NIMHD and with other programs in the country with a similar focus.