National Initiative for Minority Involvement in Neurological Clinical Trials

在临床研究，特别是临床试验中，对少数群体的招募和保留不力， 仍然是缩小健康差距的一大障碍。尽管我们已经取得了成功 我们意识到，很少有最佳实践指导方针系统地概述了成功的 促进和维持成功招募和留住少数群体的战略。这 应用程序是根据RFA-MD-11-005编写的。NIMHD与资源相关的少数民族健康和 健康差距研究(U24)。这项提案将具体涉及重点“(A)生物伦理研究 基础设施倡议。我们的目标是整合和扩展现有资源，以完善和支持 全面的多学科计划，以加强少数族裔的临床试验招募和保留 个人。该计划将由社区参与核心资源之间的合作伙伴关系领导 欧文临床翻译研究所(IICTR；UL1 RR024156)和北方 曼哈顿少数民族健康和健康差距卓越中心(NOCEMHD；P60 MD000206)。 NOCEMHD还包括曼哈顿北部比较有效性卓越中心 消除差异的研究(CER)(NOCERED；P60 MD000206PI-08S1)。CECR。NOCEMHD 和NOCERED目前进行和支持招募少数族裔进行临床试验，并在 曼哈顿北部研究中少数族裔招募的资源。我们将把这项拟议的计划称为 曼哈顿北部少数民族参与临床试验倡议(NIMICT)。的具体目标(SA) 国家信息和通信技术中心是：1)开发、试行和评估“最佳做法”工具包(工具和程序) 在临床试验中成功招募和保留少数族裔；2)扩大和 完善最近在CUMC实施的创新招聘战略，用于一般研究，用于 在临床试验中招募和保留少数群体，包括社区卫生工作者方案和卫生 扫盲方案；3)借鉴SAS 1、2的经验，并与相关利益攸关方合作， NIMHD和其他国家中心，传播我们倡议的经验，并寻求共识 制定地方和国家在临床试验中招募和保留少数族裔的指导方针。作为该计划的一部分 合作协议，我们期待着与NIMHD和其他项目在 具有类似重点的国家。

Poor recruitment and retention of minority populations in clinical research, and clinical trials in particular, continues to be a significant barrier in the reduction of health disparities. Although we have been successful we realize that there are few best-practice guidelines which have systematically outlined successful strategies to promote and sustain successful recruitment and retention of minority populations. This application was prepared in response to RFA-MD-11-005. NIMHD Resource-Related Minority Health and Health Disparities Research (U24). This proposal will specifically address focus "(a) Bioethics Research Infrastructure Initiative". Our goal is to integrate and expand existing resources to refine and support a comprehensive multidisciplinary program to enhance clinical trial recruitment and retention of minority individuals. This program will be lead by a partnership between the Community Engagement Core Resource ofthe Irving Institute for Clinical Translational Research (IICTR; UL1 RR024156) and the Northern Manhattan Center of Excellence in Minority Health and Health Disparities (NOCEMHD; P60 MD000206). NOCEMHD also includes the Northern Manhattan Center of Excellence for Comparative Effectiveness Research (CER) to Eliminate Disparities (NOCERED; P60 MD000206PI-08S1). The CECR. NOCEMHD, and NOCERED currently conduct and support recruitment of minorities for clinical trials, and are central resources for minority recruitment in research in Northern Manhattan. We will call this proposed program the Northern Manhattan Initiative for Minority involvement in Clinical Trials (NIMICT). The specific aims (SA) of NIMICT are: 1) Develop, pilot, and evaluate a toolkit of "Best Practices" (instruments and procedures) for the conduct of successful recruitment and retention of racial and ethnic minorities in clinical trials; 2) Expand and refine innovative recruitment strategies recently implemented at CUMC for general research for use in minority recruitment and retention in clinical trials, including a community health worker program and a health literacy program; 3) Building on the experience from SAs 1,2 and in collaboration with relevant stakeholders, NIMHD, and other national centers, disseminate the experience of our initiative and seek consensus to develop local and national guidelines for recruitment and retention of minorities in clinical trials. As part of the cooperative agreement, we expect significant collaboration with NIMHD and with other programs in the country with a similar focus.