Increasing Investigator Rodent Housing Capacity through the Purchase of Ventilate

通过购买通风装置增加研究人员啮齿动物的住房容量

• 批准号: 8183832
• 负责人: Jori Kay Leszczynski
• 金额: $ 49.96万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8183832
• 关键词: Animals; Basic Science; Biomedical Research; Budgets; Censuses; Chicago; Colorado; Country; Drops; Education; Ensure; Equilibrium; Equipment; Funding; Grant; Growth; Housing; Investments; Medical; Mus; Play; Principal Investigator; Research; Research Personnel; Resources; Rodent; Role; Side; Texas; Translational Research; Universities; Water; base; density; design; falls; programs; success

DESCRIPTION (provided by applicant): The Anschutz Medical Campus (AMC) at University of Colorado Denver (UC Denver) is one of the foremost and newest biomedical research centers in the country and is the largest center for biomedical research between Chicago, Texas, and the West Coast. The animal program at the UC Denver plays an important role in facilitating basic and translational research. The Universities research principal investigators have been diligent and successful in obtaining funding to support an ever expanding research enterprise on the new campus. This has resulted in an increase in the amount of funding to $412 million in Fiscal Year 2010, which represents a 16% increase over 2007 levels, or approximately 4% per year. This is a significant accomplishment in an era of shrinking research budgets and highly competitive funding. Since the new vivarium facilities opened at the AMC in January of 2004, the average daily census has increased by almost 55%. With the addition of the R2 vivarium in the fall of 2008, the University has planned for square footage to accommodate the growing research need at the University for the next several years, however, even with the significant investment into the animal program, there was a limit to the amount of funds available to complete the R2 vivarium project. As a result of project budget cutbacks, many of the racks, caging and supplies required to ensure maximum housing capacity in the R2 vivarium were not purchased on the initial project budget. Instead, a decision was made to purchase this equipment as the census numbers in the R2 facility grew. Unfortunately, the budget situation in the State of Colorado has significantly worsened over the past two years resulting in major cutbacks to Higher Education and ultimately the University of Colorado. Due to the increasing success of our principal investigators in attracting funding for research at the University, as well as high level successful recruitment efforts, the growth in the census of animals is only expected to continue to increase at a high rate. This growth will continue to cause an increased demand on the limited resources of our animal program. This application focuses on the purchase of 32 single-sided high density ventilated cage racks and turn around caging for the R2 vivarium. This equipment will provide additional housing capacity for 2,240 more cages, or an approximately 20% increase in housing capacity at the R2 vivarium helping to accommodate a growth rate of at least 5 % per year that is anticipated based on historical growth. This will have a significant positive impact for the Principal Investigators that house their mice in the R2 vivarium, allowing them to remain competitive for grants without having to limit their research effort. The high density ventilated cage racks requested in this application were designed for in the original building plans and will be hard-ducted to existing room level blowers already in place and balanced to the room. The ventilated cage racks will also be attached to existing automatic watering drops. Therefore, no renovations are requested in this application to accommodate these high density ventilated cage racks.

描述（由申请人提供）：科罗拉多大学丹佛分校（UC Denver）的Anschutz Medical Campus （AMC）是美国最重要和最新的生物医学研究中心之一，也是芝加哥，德克萨斯州和西海岸之间最大的生物医学研究中心。加州大学丹佛分校的动物项目在促进基础研究和转化研究方面发挥着重要作用。大学的主要研究人员一直勤奋并成功地获得资金，以支持新校园不断扩大的研究事业。这导致2010财政年度的资金总额增加到4.12亿美元，比2007年的水平增加16%，或每年增加约4%。在研究预算缩减和资金竞争激烈的时代，这是一项重大成就。自从2004年1月新的动物饲养设施在AMC启用以来，平均每天的人口普查增加了近55%。随着2008年秋季R2动物园内的增加，大学计划在未来几年内增加平方英尺，以适应大学不断增长的研究需求，然而，即使在动物项目上投入了大量资金，完成R2动物园内项目的资金数量也是有限的。由于项目预算削减，最初的项目预算中没有购买确保R2动物园最大住房容量所需的许多架子、笼子和用品。相反，当R2设施的人口普查数字增长时，决定购买这个设备。不幸的是，科罗拉多州的预算状况在过去两年中显著恶化，导致高等教育经费大幅削减，最终科罗拉多大学也被削减。由于我们的主要研究人员越来越成功地为大学吸引研究资金，以及高水平的成功招聘工作，预计动物普查的增长只会继续以高速度增长。这种增长将继续导致对我们有限的动物项目资源的需求增加。本申请主要是购买32个单面高密度通风笼架和翻转笼，用于R2水族箱。该设备将为2,240个笼提供额外的容纳能力，或将R2笼的容纳能力增加约20%，有助于适应根据历史增长率预计每年至少5%的增长率。这将对那些将小鼠饲养在R2动物园内的主要研究人员产生重大的积极影响，使他们能够在不限制研究努力的情况下保持对拨款的竞争。本申请中要求的高密度通风笼架是为原始建筑规划设计的，并将硬管道连接到现有的房间级鼓风机，并与房间保持平衡。通风笼架也将附在现有的自动洒水器上。因此，在这种应用中不需要翻新以容纳这些高密度通风笼架。