RCMI Multidisciplinary And Translational Research Infrastructure EXpansion Hawaii

作为美国主要的高等教育机构，从事生物医学和生物行为研究， 太平洋盆地，夏威夷大学（UH）寻求国家研究中心的支持 资源（NCRR）的研究中心在少数民族机构基础设施（RCMI）的临床和 通过PAR-09-261获得转化研究（RCTR）奖。通过RCTR奖，我们建议 在夏威夷建立RCMI多学科和转化研究基础设施扩展 （RMATRIX夏威夷或RMATRIX）作为临床和转化科学的综合“家”， 夏威夷。与RCMI转化研究网络（RTRN）合作，查尔斯德鲁大学 医学和科学，并与机构，社区为基础的，和私人合作伙伴，我们寻求重组 并扩大现有的RCMI临床和转化研究基础设施在UH。 建议的RMATRIX关键功能经过精心设计，可提供临床和翻译 研究基础设施，以扩大健康倡议，以解决整个国家的健康差距。 通过关键职能部门和健康调查团队，RMATRIX将提供必要的工具， 合作，以支持整个国家的基础，临床和翻译研究人员。鉴于呃， 它的社区合作者有相当多的基础和“从实验台到床边”的转化研究 在每一个健康倡议的经验，与RTRN翻译研究人员的合作， 临床转化科学奖（CTSA）相关机构的研究人员也将被要求在 这六个专题领域。 我们将实现我们的广泛目标，为临床和转化研究创造一个综合的家 在夏威夷通过建立和协调基础设施，包括功能， 包括：1）总体方法和治理; 2）合作和伙伴关系; 3）多学科 研究教育，培训和职业发展; 4）生物医学信息学和生物统计学; 5） 参与者和临床资源; 6）伦理和监管支持; 7）评估。

As the principal U.S. institution of higher education engaged in biomedical and biobehavioral research within the Pacific basin, the University of Hawaii (UH) seeks support from the National Center for Research Resources (NCRR) for a Research Centers in Minority Institutions Infrastructure (RCMI) for Clinical and Translational Research (RCTR) award through PAR-09-261. Through the RCTR award, we propose to establish the RCMI Multidisciplinary and Translational Research Infrastructure Expansion in Hawaii (RMATRIX Hawaii or RMATRIX) as the integrated "home" for clinical and translational science in the State of Hawaii. In collaboration with the RCMI Translational Research Network (RTRN), Charles Drew University of Medicine and Science, and with institutional, community-based, and private partners, we seek to reorganize and expand the existing RCMI clinical and translational research infrastructure at UH. The proposed RMATRIX Key Functions have been carefully designed to provide the clinical and translational research infrastructure to expand the HEALTH Initiatives to address health disparities throughout the state. Through the Key Functions and HEALTH investigative teams, RMATRIX will provide essential tools and collaboration to support basic, clinical and translational researchers throughout the state. Given that UH and its Community Collaborators have considerable basic and "bench to bedside" translational research experience in each ofthe HEALTH Initiatives, collaboration with RTRN translational researchers and investigators at Clinical Translational Science Award (CTSA) associated institutions will also be sought in these six thematic areas. We will accomplish our broad objective of creating an integrated home for clinical and translational research in Hawaii through the establishment and coordination of infrastructure that comprises functions which include: 1) Overall Approach and Governance; 2) Collaborations and Partnerships; 3) Multidisciplinary Research Education, Training and Career Development; 4) Biomedical Informatics and Biostatistics; 5) Participant and Clinical Resources; 6) Ethics and Regulatory Support; 7) Evaluation.