RCMI Multidisciplinary And Translational Research Infrastructure EXpansion Hawaii

作为美国主要的高等教育机构，从事生物医学和生物行为研究 在太平洋盆地，夏威夷大学(UH)寻求国家研究中心的支持 少数民族机构临床和医疗基础设施(RCMI)研究中心资源(NCRR) 翻译研究(RCTR)奖通过PAR-09-261。通过RCTR奖，我们建议 在夏威夷建立RCMI多学科和翻译研究基础设施扩展 (RMATRIX Hawaii或RMATRIX)作为临床和翻译科学在该州的综合“家” 夏威夷。与RCMI翻译研究网络(RTRN)合作，查尔斯·德鲁大学 医学和科学，并与机构、社区和私人伙伴合作，我们寻求重组 并扩大UH现有的RCMI临床和翻译研究基础设施。 建议的RMATRIX关键功能经过精心设计，以提供临床和翻译 研究基础设施，以扩大健康倡议，以解决全州的健康差距。 通过主要职能和健康调查小组，RMATRIX将提供必要的工具和 合作支持全州的基础、临床和转化型研究人员。鉴于UH和 它的社区合作者有相当多的基础研究和“从床到床”的翻译研究 在每一项卫生倡议、与RTRN翻译研究人员和 临床翻译科学奖(CTSA)相关机构的研究人员也将在 这六个专题领域。 我们将实现我们的广泛目标，即为临床和翻译研究创建一个综合之家 在夏威夷，通过建立和协调基础设施，这些基础设施包括 包括：1)总体方法和治理；2)协作和伙伴关系；3)多学科 研究教育、培训和职业发展；4)生物医学信息学和生物统计学；5) 参与者和临床资源；6)道德和法规支持；7)评估。

As the principal U.S. institution of higher education engaged in biomedical and biobehavioral research within the Pacific basin, the University of Hawaii (UH) seeks support from the National Center for Research Resources (NCRR) for a Research Centers in Minority Institutions Infrastructure (RCMI) for Clinical and Translational Research (RCTR) award through PAR-09-261. Through the RCTR award, we propose to establish the RCMI Multidisciplinary and Translational Research Infrastructure Expansion in Hawaii (RMATRIX Hawaii or RMATRIX) as the integrated "home" for clinical and translational science in the State of Hawaii. In collaboration with the RCMI Translational Research Network (RTRN), Charles Drew University of Medicine and Science, and with institutional, community-based, and private partners, we seek to reorganize and expand the existing RCMI clinical and translational research infrastructure at UH. The proposed RMATRIX Key Functions have been carefully designed to provide the clinical and translational research infrastructure to expand the HEALTH Initiatives to address health disparities throughout the state. Through the Key Functions and HEALTH investigative teams, RMATRIX will provide essential tools and collaboration to support basic, clinical and translational researchers throughout the state. Given that UH and its Community Collaborators have considerable basic and "bench to bedside" translational research experience in each ofthe HEALTH Initiatives, collaboration with RTRN translational researchers and investigators at Clinical Translational Science Award (CTSA) associated institutions will also be sought in these six thematic areas. We will accomplish our broad objective of creating an integrated home for clinical and translational research in Hawaii through the establishment and coordination of infrastructure that comprises functions which include: 1) Overall Approach and Governance; 2) Collaborations and Partnerships; 3) Multidisciplinary Research Education, Training and Career Development; 4) Biomedical Informatics and Biostatistics; 5) Participant and Clinical Resources; 6) Ethics and Regulatory Support; 7) Evaluation.