RCMI Multidisciplinary And Translational Research Infrastructure EXpansion Hawaii

描述（由申请人提供）：夏威夷大学（UH）作为美国在太平洋盆地从事生物医学和生物行为研究的主要高等教育机构，寻求国家研究资源中心（NCRR）的支持，通过PAR-09-261获得少数民族机构基础设施研究中心（RCMI）的临床和转化研究（RCTR）奖。通过RCTR奖，我们建议在夏威夷建立RCMI多学科和转化研究基础设施扩展（RMATRIX夏威夷或RMATRIX），作为夏威夷州临床和转化科学的综合“家”。我们与RCMI转化研究网络（RTRN）、查尔斯德鲁医学与科学大学以及机构、社区和私人合作伙伴合作，寻求重组和扩大休斯敦大学现有的RCMI临床和转化研究基础设施。

DESCRIPTION (provided by applicant): As the principal U.S. institution of higher education engaged in biomedical and biobehavioral research within the Pacific basin, the University of Hawaii (UH) seeks support from the National Center for Research Resources (NCRR) for a Research Centers in Minority Institutions Infrastructure (RCMI) for Clinical and Translational Research (RCTR) award through PAR-09-261. Through the RCTR award, we propose to establish the RCMI Multidisciplinary and Translational Research Infrastructure Expansion in Hawaii (RMATRIX Hawaii or RMATRIX) as the integrated "home" for clinical and translational science in the State of Hawaii. In collaboration with the RCMI Translational Research Network (RTRN), Charles Drew University of Medicine and Science, and with institutional, community-based, and private partners, we seek to reorganize and expand the existing RCMI clinical and translational research infrastructure at UH. The proposed RMATRIX Key Functions have been carefully designed to provide the clinical and translational research infrastructure to expand the HEALTH Initiatives to address health disparities throughout the state. Through the Key Functions and HEALTH investigative teams, RMATRIX will provide essential tools and collaboration to support basic, clinical and translational researchers throughout the state. Given that UH and its Community Collaborators have considerable basic and "bench to bedside" translational research experience in each of the HEALTH Initiatives, collaboration with RTRN translational researchers and investigators at Clinical Translational Science Award (CTSA) associated institutions will also be sought in these six thematic areas. We will accomplish our broad objective of creating an integrated home for clinical and translational research in Hawaii through the establishment and coordination of infrastructure that comprises functions which include: 1) Overall Approach and Governance; 2) Collaborations and Partnerships; 3) Multidisciplinary Research Education, Training and Career Development; 4) Biomedical Informatics and Biostatistics; 5) Participant and Clinical Resources; 6) Ethics and Regulatory Support; 7) Evaluation. PUBLIC HEALTH RELEVANCE (provided by applicant): RMATRIX seeks to fulfill its overall objective of creating an integrated academic home for clinical and translational research designed to improve health outcomes in Hawaii's diverse populations. By facilitating the research process through consolidation and coordination of Key Functions, RMATRIX will contribute to the reduction and elimination of health disparities across the RCMI community.