RCMI Multidisciplinary And Translational Research Infrastructure EXpansion Hawaii

描述(由申请人提供)：作为太平洋盆地内从事生物医学和生物行为研究的美国主要高等教育机构，夏威夷大学(UH)寻求国家研究资源中心(NCRR)的支持，通过PAR-09-261授予少数族裔机构基础设施研究中心(RCMI)临床和翻译研究(RCTR)奖。通过RCTR奖，我们建议在夏威夷建立RCMI多学科和转化性研究基础设施扩展(RMATRIX Hawaii或RMATRIX)，作为临床和转化性科学在夏威夷州的综合“家”。通过与RCMI转化研究网络(RTRN)、查尔斯·德鲁医学与科学大学以及机构、社区和私人合作伙伴的合作，我们寻求重组和扩大UH现有的RCMI临床和转化研究基础设施。 拟议的RMATRIX关键功能经过精心设计，以提供临床和翻译研究基础设施，以扩大卫生倡议，以解决全州的健康差距。通过关键职能和健康调查团队，RMATRIX将提供必要的工具和合作，以支持全州的基础、临床和翻译研究人员。鉴于明尼苏达大学及其社区合作者在每一项健康倡议中都有相当多的基础和“从床到床”的翻译研究经验，也将在这六个主题领域寻求与RTRN翻译研究人员和临床翻译科学奖(CTSA)相关机构的研究人员的合作。 我们将通过建立和协调基础设施来实现我们的广泛目标，即在夏威夷创建临床和转化研究的综合之家，基础设施包括以下功能：1)整体方法和治理；2)合作和伙伴关系；3)多学科研究教育、培训和职业发展；4)生物医学信息学和生物统计学；5)参与者和临床资源；6)伦理和监管支持；7)评估。 公共卫生相关性(由申请者提供)：RMATRIX寻求实现其总体目标，即为临床和翻译研究创建一个综合的学术之家，旨在改善夏威夷不同人群的健康结果。通过巩固和协调关键职能，促进研究进程，RMATRIX将有助于减少和消除整个RCMI社区的健康差距。

DESCRIPTION (provided by applicant): As the principal U.S. institution of higher education engaged in biomedical and biobehavioral research within the Pacific basin, the University of Hawaii (UH) seeks support from the National Center for Research Resources (NCRR) for a Research Centers in Minority Institutions Infrastructure (RCMI) for Clinical and Translational Research (RCTR) award through PAR-09-261. Through the RCTR award, we propose to establish the RCMI Multidisciplinary and Translational Research Infrastructure Expansion in Hawaii (RMATRIX Hawaii or RMATRIX) as the integrated "home" for clinical and translational science in the State of Hawaii. In collaboration with the RCMI Translational Research Network (RTRN), Charles Drew University of Medicine and Science, and with institutional, community-based, and private partners, we seek to reorganize and expand the existing RCMI clinical and translational research infrastructure at UH. The proposed RMATRIX Key Functions have been carefully designed to provide the clinical and translational research infrastructure to expand the HEALTH Initiatives to address health disparities throughout the state. Through the Key Functions and HEALTH investigative teams, RMATRIX will provide essential tools and collaboration to support basic, clinical and translational researchers throughout the state. Given that UH and its Community Collaborators have considerable basic and "bench to bedside" translational research experience in each of the HEALTH Initiatives, collaboration with RTRN translational researchers and investigators at Clinical Translational Science Award (CTSA) associated institutions will also be sought in these six thematic areas. We will accomplish our broad objective of creating an integrated home for clinical and translational research in Hawaii through the establishment and coordination of infrastructure that comprises functions which include: 1) Overall Approach and Governance; 2) Collaborations and Partnerships; 3) Multidisciplinary Research Education, Training and Career Development; 4) Biomedical Informatics and Biostatistics; 5) Participant and Clinical Resources; 6) Ethics and Regulatory Support; 7) Evaluation. PUBLIC HEALTH RELEVANCE (provided by applicant): RMATRIX seeks to fulfill its overall objective of creating an integrated academic home for clinical and translational research designed to improve health outcomes in Hawaii's diverse populations. By facilitating the research process through consolidation and coordination of Key Functions, RMATRIX will contribute to the reduction and elimination of health disparities across the RCMI community.