Shared Resources - Tissue Procurement

共享资源 - 组织采购

• 批准号: 8533966
• 负责人: George J. Weiner
• 金额: $ 0.3万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至 2016-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8533966
• 关键词: Basic Science; Benign; Blood; Cancer Center Support Grant; Clinic; Clinical Data; Collection; Computer software; Consent; DNA; Databases; Freezing; Future; Goals; Human; Human Resources; Individual; Informatics; Institution; Instruction; Laboratories; Lead; Leadership; Link; Malignant - descriptor; Malignant Neoplasms; Medical; Medical center; Normal tissue morphology; Operative Surgical Procedures; Patient Care; Patients; Procedures; Quality Control; Regulation; Research; Research Infrastructure; Research Personnel; Resource Sharing; Resources; Sampling; Science; Secure; Services; Source; Specimen; Surgical Pathology; Suspension substance; Suspensions; Time; Tissue Procurements; Tissues; Translating; Translational Research; Universities; Work; anticancer research; base; design; human tissue; meetings; neoplasm resource; operation

PROJECT SUMMARY (See instructions): Tissue Procurement Core Ready access to both benign and malignant tissue is a valuable resource for cancer investigators. The Tissue Procurement Core is designed to collect and store high quality tissue specimens from a variety of sources and make these available to HCCC investigators based on the science proposed. The Core insures that these activities are performed in compliance with all rules and regulations covering such activity. The Core and its personnel work in cooperation with clinicians from various departments to: 1) Identify and consent patients from whom collection may be appropriate. 2) Work closely with appropriate individuals in the Surgical Pathology Laboratory to insure adequate patient care while maximizing the number of collected specimens 3) Enter information about specimens into a secure data base and store appropriately 4) Implement rigorous quality control procedures 5) Distribute available tissue to investigators for high quality cancer research The HCCC and University of lowa CTSA are collaborating to further strengthen access to biospecimens. The Tissue Procurement Core has implemented CaTISSUE to enhance the informatics infrastructure for Tissue Procurement, and is working to develop an approach to obtaining consent at the time of registration to the medical center, and link tissues with deidentified clinical data, that will further enhance the utility of tissue for HCCC investigators.

项目总结（见说明）： 组织采购核心 容易获得良性和恶性组织是癌症的宝贵资源 investigators.组织采购核心旨在收集和储存高质量的 组织标本从各种来源，并使这些可用于HCCC研究人员的基础上提出的科学。核心委员会确保这些活动的开展符合涉及此类活动的所有规则和条例。该中心及其工作人员与各部门的临床医生合作，以： 1)识别并同意可能适合采集的患者。 2)与外科病理学实验室的相关人员密切合作，确保在最大限度地收集样本数量的同时提供充分的患者护理 3)将有关标本的信息输入安全数据库并妥善保存 4)实施严格的质量控制程序 5)将可用组织分发给研究人员，以进行高质量的癌症研究 HCCC和爱荷华大学CTSA正在合作，以进一步加强获得 生物标本组织采购核心已经实施了CaTISSUE，以加强组织采购的信息基础设施，并正在努力开发一种在向医疗中心注册时获得同意的方法，并将组织与去识别的临床数据联系起来，这将进一步提高组织对HCCC研究者的效用。