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Animal Carcinogenesis Core - Developmental Funds

动物致癌核心 - 发展基金

基本信息

批准号：
8369407
负责人：
MICHELE CARBONE
金额：
$ 6.17万
依托单位：
UNIVERSITY OF HAWAII AT MANOA
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-07-01 至 2017-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8369407
关键词：
Administrator Allografting Animal Experiments Animal Husbandry Animal Model Animals Arts Award Basic Science Behavioral Biometry Biostatistics Shared Resource Biotechnology Blood specimen Budgets Burn injury Caliber Cancer Biology Cancer Burden Cancer Center Cancer Center Support Grant Capital Carcinogens Charge Clinical Clinical Research Clinical Trials Collaborations Consultations Core Facility DNA Data Data Analyses Databases Development Diagnostic Diagnostic Services Direct Costs Disease Education Emergency Care Engineering Ensure Environment Epidemiology Equipment Experimental Animal Model Extramural Activities Faculty Feasibility Studies Fees Formalin Foundations Freezing Funding Funding Mechanisms Future Genetically Engineered Mouse Genomics Genotype Goals Grant Guidelines Harvest Hawaii Health Health Services Accessibility Hematoxylin and Eosin Staining Method Histology Human Human Resources Image Immunohistochemistry Immunology In Vitro Inflammation Institution Investigational Drugs Investigator-Initiated Research Investments Joints Laboratories Laboratory Animals Lead Leadership Malignant Neoplasms Medical center Methods Microscopy Mission Modeling Molecular Molecular Genetics Monitor Mouse Strains Mus NCI Center for Cancer Research Neoplasm Metastasis Normal tissue morphology Paraffin Embedding Pathology Pharmacologic Substance Phenotype Physicians Physiological Pilot Projects Play Preparation Primary Neoplasm Procedures Protocols documentation Records Recruitment Activity Refuse Disposal Reporting Research Research Personnel Research Support Resource Development Resource Sharing Resources Rodent Role Route Running Safety Sample Size Sampling Schools Scientist Secure Series Services Staining method Stains Structure Techniques Therapeutic Thoracic Oncology Tissue Banking Tissue Banks Tissue Harvesting Tissue Sample Training Translating Translational Research Translations Tumor Bank Tumor Cell Line Tumor Tissue Universities Update Validation Wages Work Xenograft Model analytical method anticancer research base cancer cell carcinogenesis chemical carcinogen clinically relevant computerized tools cost data mining design disease diagnosis drug development drug testing environmental carcinogenesis exposed human population hazard health administration in vivo informatics shared resource inhibitor/antagonist innovation interest laboratory accident laboratory facility medical schools meetings member novel preclinical study prevent programs research study sample collection sound success tumor tumor growth tumor initiation web site

项目摘要

Developmental funds are instrumental in supporting faculty recruitment bridge funding, pilot project funding and the establishment of the new Animal Carcinogenesis Core at the University of Hawai'i Cancer Center (UHCC). Achieving the mission and long-term goals UHCC is dependent upon the ability to recruit the highest caliber scientists with clinical, basic, behavioral, epidemiological expertise who can lead high impact investigator initiated research, strengthen research collaborations among members of the Hawai'i Cancer Consortium (HCC), and advance the translational research agenda of UHCC. In the current grant cycle limited CCSG funds were available for use as developmental funds and a majority of the funds were used for strategic recruitments, including the recruitment of Dr. Michele Carbone in 2006, who is now the Director of UHCC. CCSG Developmental Funds were used to support 2 additional recruitments - Dr. Iona Cheng, who is the recipient of a V Foundation award and 2 R01 grants and Dr. Unhee Lim, who was awarded an AICR grant. Bridge funding will provide support for interim salaries and research support for promising investigators. Pilot grants will enable the development of new collaborative initiatives. The newly proposed Animal Carcinogenesis Core will enhance UHCC opportunities to utilize state-of-art animal models for translational cancer research, a murine tumor tissue bank, and expert consultation regarding animal experiments. CCSG developmental funds will ultimately continue to help UHCC leverage significant institutional and philanthropic support, a portion of which has been invested into providing pilot funding and bridge funding to UHCC faculty, many of which have led to new or renewal R01 or equivalent NCI-approved cancer-focused funding. The past success of the CCSG and institutional Developmental Funds reflects the sound leadership of and oversight mechanisms in place to ensure appropriate use.

发展基金有助于支持夏威夷大学癌症中心 (UHCC) 的教师招聘过桥资金、试点项目资金以及建立新的动物致癌核心。实现使命和长期目标 UHCC 依赖于招募具有临床、基础、行为、流行病学专业知识的最高水平科学家的能力，他们可以领导高影响力的研究者发起的研究，加强夏威夷癌症联盟 (HCC) 成员之间的研究合作，并推进 UHCC 的转化研究议程。在当前的资助周期中，有限的 CCSG 资金可用作发展基金，大部分资金用于战略招聘，包括 2006 年招聘 Michele Carbone 博士，他现在是 UHCC 的主任。 CCSG 发展基金用于支持另外 2 名招募人员：Iona Cheng 博士（获得 V 基金会奖和 2 项 R01 补助金）和 Unhee Lim 博士（获得 AICR 补助金）。过桥资金将为有前途的研究人员提供临时工资和研究支持。试点赠款将有助于制定新的合作举措。新提出的动物致癌核心将增加 UHCC 的机会，利用最先进的动物模型进行转化癌症研究、鼠肿瘤组织库和有关动物实验的专家咨询。 CCSG 发展基金最终将继续帮助 UHCC 利用重要的机构和慈善支持，其中一部分已投入为 UHCC 教员提供试点资金和过渡资金，其中许多资金已导致新的或更新的 R01 或同等 NCI 批准的癌症重点资金。 CCSG 和机构发展基金过去的成功反映了为确保适当使用而建立的良好领导和监督机制。