PSWRCE Cpmprehensive Program Training Program for High Containment Lab

美国面临潜在生物恐怖主义袭击的严重公共卫生威胁，自然 新出现的传染病。由于联邦政府最近对生物防御研究的兴趣， 人们越来越关注制定预防、治疗和诊断此类感染的策略。一个重要的 这项研究的一部分需要使用 BSL、BSL 增强型和 ABSL 设施。 随着全国和全球范围内 BSL 实验室数量的逐年增加，需要培训合格的人员 研究人员、BSO、运营/支持行业人员和急救人员呈指数级增长。一个典型的 学术环境中的 BSL 实验室可能有 5-10 名研究人员或技术人员、1 名或 2 名 BSO，以及 5-25 名 负责运营和维护的设施/行业人员。此外，还有数百人 可能会参与应对这些高防护实验室的紧急情况，包括 警察、消防、护理人员和危险品人员。这些不同的个体必须有效地互动 确保设施内外采取高度协调的方法。如果没有综合努力，研究 可能会在不太安全的环境中进行，从而受到损害。此外，公众对 高密闭实验室的安全性将通过充分、专业的意识而大大提高。 各个级别的培训。然而，迄今为止，尚未制定任何此类培训的国家标准。 目标群体。 目前，美国为研究人员或 BSO 提供了三个高级培训项目。有些使用模拟 实验室设施，使研究人员能够在设备和设施紧密匹配的环境中进行培训 BSL 实验室内的条件。该模拟环境提供基于行为的培训， 表现出比传统课堂学习过程更有效的结果（Kaufman & Berkelman， 应用生物安全，第 12 卷，第 3 期，2007 年）。 运营和支持人员的培训也可通过课堂课程进行： 美国的多个站点可以通过 Frontline Foundation 与 国家生物安全生物防护培训计划（NBBTP）。该课程混合了核心课程和选修课程 并为完成 4O 小时实习练习（个人）的学生提供可选证书 安排在学生自己的设施中）。美国没有其他培训项目为学生提供实践培训 使用通常在高防护实验室之外找到的真实设备，尽管加拿大政府已经 一个使用真实实验室设施的项目每年暂时关闭一次以进行培训。 显然迫切需要为这三个目标开发培训设施和方案 使用实验室模拟和设备的小组。室内外配备齐全的模拟实验室设施是最安全、最可靠的。 实际操作设施的最实用替代方案。我们建议的培训设施和课程将准备 所有三个目标群体都能在该国任何 BSL 设施中安全地开展工作。

The United States faces serious public health threats from potential bioterrorism attacks and naturally emerging infectious diseases. Due to the federal government's recent interest in biodefense research, there has been an increasing focus on developing strategies to prevent, treat and diagnose such infections. A significant portion of this research requires the use of BSLs, BSLs-enhanced, and ABSLs facilities. As the number of BSLs labs increases nationally and world-wide each year, the need to train qualified researchers, BSOs, operations/support trades personnel and first responders increases exponentially. A typical BSLs lab in an academic setting may have 5-10 researchers or technicians, i or 2 BSOs, and 5-25 facilities/trades personnel responsible for operations and maintenance. Additionally, several hundred people may become involved in responding to an emergency situation at these high-containment labs, including police, fire, paramedic, and hazmat personnel. This diverse array of individuals must interact effectively to ensure a highly coordinated approach inside and outside the facility. Without an integrated effort, research may be conducted in a less than optimally safe setting and thus compromised. Further, public confidence in the safety of high-containment labs would be greatly enhanced by an awareness of adequate, specialized training at every level. Nevertheless, a national standard thus far has not been set for training any of these target groups. Currently, the U.S. has three advanced training programs for researchers or BSOs. Some use a mock lab facility, enabling the researchers to train in an environment where equipment and facility closely match conditions inside BSLs laboratories. This simulated environment provides behavioral-based training that has demonstrated more effective results than the traditional classroom learning process (Kaufman & Berkelman, Applied Biosafety, Vol 12, No. 3, 2007). Training for Operations and Support personnel is also available through classroom-based courses at various sites in the U.S. One such program is available through the Frontline Foundation in conjunction with the National Biosafety Biocontainment Training Program (NBBTP). The course mixes core and elective classes and provides an optional certificate for students who complete a 4O-hour practicum exercise (individually arranged at the student's own facility). No other training program in the U.S. offers students hands-on training using real equipment typically found outside the high-containment lab, although the Canadian government has a program that uses real lab facilities temporarily shut down once each year for training. There is clearly an urgent need to develop both training facilities and programs for the three target groups using lab simulation and equipment. A mock lab facility equipped inside and outside is the safest and most practical alternative to real operational facilities. Our proposed training facility and courses will prepare all three target groups to perform their jobs safely at any BSLs facility in the country.