PSWRCE Cpmprehensive Program Training Program for High Containment Lab

美国面临着来自潜在生物恐怖袭击的严重公共卫生威胁， 新出现的传染病由于联邦政府最近对生物防御研究的兴趣， 越来越多的人关注制定预防、治疗和诊断此类感染的战略。显著 本研究的一部分需要使用BSL、BSL增强型和ABSL设施。 随着BSL实验室的数量每年在全国和世界范围内增加， 研究人员、BSO、运营/支持行业人员和第一反应人员呈指数级增长。典型的 在学术环境中的BSL实验室可能有5-10名研究人员或技术人员，1或2名BSO，5-25名 负责操作和维护的设施/行业人员。此外，数百人 可能会参与应对这些高防护实验室的紧急情况，包括 警察消防员护理人员和危险品处理人员这些不同的人必须有效地相互作用， 确保设施内外的高度协调。如果不进行综合努力，研究 可能在低于最佳安全设置的情况下进行，从而受到损害。此外，公众对 通过充分的、专业的、 各级培训。然而，到目前为止，还没有为培训这些人制定国家标准。 目标群体。 目前，美国有三个针对研究人员或BSO的高级培训项目。有些人使用模拟 实验室设施，使研究人员能够在设备和设施紧密匹配的环境中进行培训 BSL实验室内的条件。这种模拟环境提供了基于行为的培训， 证明了比传统的课堂学习过程更有效的结果（考夫曼& Berkelman， Applied Biosafety，2007年，第12期，第3期）。 运营和支持人员的培训也可以通过课堂课程获得， 在美国的各种网站。一个这样的计划是通过前线基金会与 国家生物安全生物防护培训计划（NBBTP）。这门课混合了核心课和选修课 并为完成40小时实习练习的学生（单独）提供可选证书 在学生自己的设施安排）。在美国，没有其他培训项目为学生提供实践培训 使用通常在高密封实验室外找到的真实的设备，尽管加拿大政府已经 该项目使用真实的实验室设施，每年临时关闭一次进行培训。 显然迫切需要为这三个目标发展培训设施和方案 使用实验室模拟和设备。一个模拟实验室设施配备内外是最安全的， 最实用的替代真实的操作设施。我们建议的培训设施和课程将为 所有这三个目标群体在该国任何BSL设施安全地执行他们的工作。

The United States faces serious public health threats from potential bioterrorism attacks and naturally emerging infectious diseases. Due to the federal government's recent interest in biodefense research, there has been an increasing focus on developing strategies to prevent, treat and diagnose such infections. A significant portion of this research requires the use of BSLs, BSLs-enhanced, and ABSLs facilities. As the number of BSLs labs increases nationally and world-wide each year, the need to train qualified researchers, BSOs, operations/support trades personnel and first responders increases exponentially. A typical BSLs lab in an academic setting may have 5-10 researchers or technicians, i or 2 BSOs, and 5-25 facilities/trades personnel responsible for operations and maintenance. Additionally, several hundred people may become involved in responding to an emergency situation at these high-containment labs, including police, fire, paramedic, and hazmat personnel. This diverse array of individuals must interact effectively to ensure a highly coordinated approach inside and outside the facility. Without an integrated effort, research may be conducted in a less than optimally safe setting and thus compromised. Further, public confidence in the safety of high-containment labs would be greatly enhanced by an awareness of adequate, specialized training at every level. Nevertheless, a national standard thus far has not been set for training any of these target groups. Currently, the U.S. has three advanced training programs for researchers or BSOs. Some use a mock lab facility, enabling the researchers to train in an environment where equipment and facility closely match conditions inside BSLs laboratories. This simulated environment provides behavioral-based training that has demonstrated more effective results than the traditional classroom learning process (Kaufman & Berkelman, Applied Biosafety, Vol 12, No. 3, 2007). Training for Operations and Support personnel is also available through classroom-based courses at various sites in the U.S. One such program is available through the Frontline Foundation in conjunction with the National Biosafety Biocontainment Training Program (NBBTP). The course mixes core and elective classes and provides an optional certificate for students who complete a 4O-hour practicum exercise (individually arranged at the student's own facility). No other training program in the U.S. offers students hands-on training using real equipment typically found outside the high-containment lab, although the Canadian government has a program that uses real lab facilities temporarily shut down once each year for training. There is clearly an urgent need to develop both training facilities and programs for the three target groups using lab simulation and equipment. A mock lab facility equipped inside and outside is the safest and most practical alternative to real operational facilities. Our proposed training facility and courses will prepare all three target groups to perform their jobs safely at any BSLs facility in the country.