Maintenance and Improvement of NINDS Infrastructure

2012财年，以下实验室和研究支持区域进行了重大翻新： 为电路动力学和连接部主任Kevin Briggman博士翻新电生理学和成像/显微镜实验室。位置，NIH贝塞斯达校区，35号楼 为阿方索·席尔瓦博士翻新动物成像和生理学实验室空间，脑微循环股主任。位置，NIH贝塞斯达校区，49号楼 为魏路·席尔瓦博士改造电生理学和细胞培养实验室，脑微循环单位主任。位置，NIH贝塞斯达校区，35号楼 为神经系统感染科科长阿维·纳特博士翻新化学实验室。位置，NIH贝塞斯达校区，10号楼 为阿方索·席尔瓦博士翻新显微镜和基本实验室空间，脑微循环股主任。位置，NIH贝塞斯达校区，49号楼 翻新NIH贝塞斯达校区外科神经科主任Russ Lonser博士的基础实验室，10号楼 搬迁和激活活动为波特神经科学研究中心二期混合研究所实验室大楼，与NINDS有牵头研究所。位置，NIH贝塞斯达校区，36号楼 购买了以下主要共享设备，以支持大量PI： -卡尔蔡司LSM 780 34通道光谱探测系统，带有GaAsP外部探测器，用于功能和分子成像实验室的多光子和单光子成像 -升级现有徕卡共聚焦显微镜，配备脉冲白光激光，并为光成像设施提供门控荧光检测能力 -NINDS流式细胞仪核心设备的10通道荧光显微镜成像系统 -Orbitrap Elite 10000，带水循环器，用于多肽测序设施 -波特神经科学研究中心二期的服务器机房基础设施，这是一座混合研究所的实验室大楼，NINDS拥有牵头研究所 -用于功能和分子成像实验室的17.6T磁体的磁共振成像和光谱控制台

The following laboratories and research support areas underwent major renovations during FY 2012: Renovate Electrophysiology and imaging/microscopy laboratory for Dr. Kevin Briggman, Chief, Circuit Dynamics and Connectivity Unit. Location, NIH Bethesda Campus, Bldg 35 Renovate animal imaging and physiology laboratory space for Dr. Afonso Silva , Chief, Cerebral Microcirculation Unit. Location, NIH Bethesda Campus, Bldg 49 Renovate electrophysiology and cell culture laboratory for Dr. Wei Lu Silva, Chief, Cerebral Microcirculation Unit. Location, NIH Bethesda Campus, Bldg 35 Renovate chemistry laboratory for Dr. Avi Nath, Chief, Section of Infections of the Nervous Systems. Location, NIH Bethesda Campus, Bldg 10 Renovate microscopy and basic laboratory space for Dr. Afonso Silva , Chief, Cerebral Microcirculation Unit. Location, NIH Bethesda Campus, Bldg 49 Renovate basic laboratory for Dr. Russ Lonser, Chief, Surgical Neurology Branch, Location, NIH Bethesda Campus, Bldg 10 Relocation and activation activities for the Porter Neuroscience Research Center Phase 2, Mixed institute laboratory building, with NINDS has the lead institute. Location, NIH Bethesda Campus, Bldg 36 The following pieces of major shared equipment were purchased to support a large number of PIs: - Carl Zeiss LSM 780 34 Channel Spectral Detection system with GaAsP external detectors for Multi-photon and Single photon imaging for the Laboratory of Functional and Molecular Imaging - Upgrade existing Leica confocal microscope with pulsed white-light laser and capability for gated fluorescence detection for the Light Imaging Facility - 10-channel fluorescence microscope imaging system for the NINDS Flow Cytometry Core Facility - Orbitrap Elite 10000 with water recirculator for the Peptide Sequencing Facility - Infrastructure for server room for the Porter Neuroscience Research Center Phase 2, a mixed institute laboratory building, with NINDS has the lead institute - A Magnetic Resonance Imaging and Spectroscopy Console for a 17.6T Magnet for The Laboratory of Functional and Molecular Imaging