Maintenance and Improvement of NINDS Infrastructure

美国国立卫生研究院NINDS设施规划/设备 35号楼，GF352-4 2013财年，以下实验室和研究支持区域进行了翻新： 1.为电路动力学和连接部主管Kevin Briggman博士翻新电生理学和成像/显微镜。地点，NIH校区，35号楼。 2.为阿方索·席尔瓦博士翻新动物成像和生理学实验室空间，脑微循环股主任。地点，NIH贝塞斯达校区，35号楼。 3.翻新国立卫生研究院贝塞斯达校区10号楼外科神经科主任Russ Lonser博士的显微镜和基础实验室。 4.波特神经科学研究中心二期混合研究所实验室大楼的搬迁和激活活动，NINDS是牵头研究所。地点，NIH贝塞斯达校区，36号楼。 5.翻新神经元细胞骨架蛋白调节科科长Harish Pant博士的办公室。地点，NIH校区，49号楼。 6.搬迁和翻新与外科神经科有关的动物程序室，并与NINDS兽医工作人员合作。地点，NIH贝塞斯达校区，49号楼。 7.为电路动力学和连接部主管Kevin Briggman博士进行引擎盖升级和相关的实验室翻新。地点，NIH校区，37号楼。 8.为树枝状晶体形态发生和可塑性股科长权远博士进行实验室翻新和装修。地点，NIH贝塞斯达校区，35号楼。 9.为分子生理学和生物物理科科长Kenton Swartz博士翻新范围房间。地点，NIH贝塞斯达校区，35号楼。 10.为NINDS/NIMH仪器科翻修办公室，供仪表科科长George Dold使用。地点，NIH贝塞斯达校区，13号楼。 11.翻新和搬迁Abhik Ray-Chaudhury博士办公室。地点，NIH贝塞斯达校区，10号楼。 12.为临床主任办公室主任阿维·纳特博士翻修临床中心候诊室。地点，NIH贝塞斯达校区，10号楼。 13.F翼项目混合研究所实验室翼的搬迁和激活活动。实验室建设包括为三个PI的实验室和办公室工作，他们是FACS设施主任Dragan Maric博士、分子医学和病毒学科主任Gene Maje博士以及病毒免疫学和活体成像科主任Dorian McGvern博士。地点，NIH贝塞斯达校区，10号楼。 购买了以下主要共享设备，以支持大量PI： 1.将现有的Thermo Orbitrap Velos质谱仪升级为用于临床蛋白质组学单位的Thermo Orbitrap Elite等价物 2.临床蛋白质组学单位的岛津无限工作站 3.蛋白质/多肽测序设备的MicroLab液体处理机 4.为国家关节炎、肌肉骨骼和皮肤病研究所(NIAMS)和国家神经疾病和中风研究所(NINDS)之间的合作项目提供自动化TALEN 5.11.7T功能与分子成像实验室动物磁共振超导磁体系统 6.作为国家酒精滥用和酒精中毒研究所(NIAAA)、国家儿童健康和人类发展研究所(NICHD)、国家药物滥用研究所(NIDA)、国家精神健康研究所(NIMH)和国家神经疾病和中风研究所(NINDS)共同倡议的一部分，用于人脑成像的3T磁共振系统 7.用于功能和分子成像实验室的超高动物MRI的集成垫片的动物成像梯度

NATIONAL INSTITUTES OF HEALTH NINDS Facilities Planning / Equipment Bldg 35, GF352-4 The following laboratories and research support areas underwent renovations during FY 2013: 1. Renovate Electrophysiology and imaging/ microscopy for Dr Kevin Briggman, Chief, Circuit Dynamics and Connectivity unit. Location, NIH Campus, Bldg 35. 2. Renovate animal imaging and physiology laboratory space for Dr Alfonso Silva, Chief, Cerebral Microcirculation Unit. Location, NIH Bethesda Campus, Bldg 35. 3. Renovate microscopy and basic laboratory for Dr Russ Lonser, Chief, Surgical Neurology Branch, Location, NIH Bethesda Campus, Building 10. 4. Relocation and activation activities for the Porter Neuroscience Research Center Phase 2, Mixed institute laboratory building, with NINDS as the lead institute. Location, NIH Bethesda Campus, Bldg 36. 5. Renovate the office of Dr Harish Pant, Chief, Neuronal Cytoskeletal Protein Regulation Section. Location, NIH Campus, Bldg 49. 6. Relocate and renovate an Animal Procedure Room Associated with the Surgical Neurology Branch in conjunction with the NINDS Veterinary Staff. Location, NIH Bethesda Campus, Bldg 49. 7. Perform Hood upgrade and associated laboratory renovation for Dr Kevin Briggman, Chief, Circuit Dynamics and Connectivity unit. Location, NIH Campus, Bldg 37. 8. Perform a lab renovation and fit-out for Dr Quan Yuan, Chief, Dendrite Morphogenesis and Plasticity Unit. Location, NIH Bethesda Campus, Bldg 35. 9. Renovate Scope Room for Dr Kenton Swartz, Chief, Molecular Physiology & Biophysics Section. Location, NIH Bethesda Campus, Bldg 35. 10. Renovate offices for the NINDS/ NIMH Section on Instrumentation for George Dold, Chief, Section on Instrumentation (NIMH). Location, NIH Bethesda Campus, Bldg 13. 11. Renovate and Relocate the Office for Dr Abhik Ray-Chaudhury. Location, NIH Bethesda Campus, Bldg 10. 12. Renovate the Clinical Center On-Call Room for Dr Avi Nath, Director, Office of the Clinical Director. Location, NIH Bethesda Campus, Bldg 10. 13. Relocation and activation activities for the F-Wing project, Mixed institute laboratory wing. Laboratory construction includes work for laboratories and offices for three PIs, Dr Dragan Maric Chief, FACS Facility, Dr Gene Major, Chief, Molecular Medicine & Virology Section, and Dr Dorian McGavern, Chief, Viral Immunology and Intravital Imaging Section. Location, NIH Bethesda Campus, Bldg 10. The following pieces of major shared equipment were purchased to support a large number of PIs: 1. Upgrade existing Thermo Orbitrap Velos mass spectrometer to Thermo Orbitrap Elite equivalent for the Clinical Proteomics Unit 2. Shimadzu Perfinity Workstation for the Clinical Proteomics Unit 3. Microlab Liquid Handler for the Protein/Peptide Sequencing Facility 4. Automated TALEN for a collaborative project between the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and National Institute of Neurological Disorders and Stroke (NINDS) 5. 11.7T Superconducting Magnet system for MRI of animals for the Laboratory of Functional and Molecular Imaging 6. 3T MRI System for human brain imaging as part of a shared initiative between the National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institute of Child Health and Human Development (NICHD), National Institute on Drug Abuse (NIDA), National Institute of Mental Health (NIMH), and National Institute of Neurological Disorders and Stroke (NINDS) 7. Animal imaging gradient with integrated shims for ultra-high animal MRI for the Laboratory of Functional and Molecular Imaging