FASEB SRC on From Causes to Consequences, to Treatment: Obesity in Perspective
FASEB SRC 探讨从原因到后果,再到治疗:肥胖的视角
基本信息
- 批准号:8400279
- 负责人:
- 金额:$ 1.8万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2012
- 资助国家:美国
- 起止时间:2012-07-15 至 2013-06-30
- 项目状态:已结题
- 来源:
- 关键词:AcademiaAddressAdipose tissueAdultAreaBasic ScienceBehaviorBehavioral GeneticsBiological FactorsBody WeightClinicalCollaborationsCommunitiesComorbidityComplexDepositionDevelopmentEnvironmentEnvironmental Risk FactorFosteringGenesHeterogeneityIndividualIndustryInvestigationLeadLife StyleLipidsMetabolic DiseasesMethodsNatureObesityOverweightPatternPhysiologyPopulationPrevalencePreventionPrevention programPreventiveProcessPublic HealthPublic PolicyRegulationResearchResearch DesignResearch PersonnelRiskScientistShapesUnited States Dept. of Health and Human ServicesWorkbasecareer developmentdesigneffective therapyfallsholistic approachimprovedmeetingsobesity in childrenobesity treatmentpre-clinicalsuccesssymposiumtreatment program
项目摘要
DESCRIPTION (provided by applicant): Among the adult population of the US it is now estimated that over 60 percent are overweight or obese, and the prevalence of childhood obesity is increasing at a staggering rate. The Department of Health and Human Services has ranked obesity among the most significant public health threats/burdens of the twenty-first century. To date efforts at prevention and treatment for obesity have met with mixed success, undoubtedly reflecting the underlying heterogeneity in its origin and expression. Therefore, given the multitude of factors impacting body weight regulation, patterns of lipid deposition, and adipose tissue function and their impact on metabolic and disease processes, it is critical for the
field of obesity research to seek an integrative perspective in order to better understand the intricate interplay between genetics, behavior, and the external environment in order to identify the most productive avenues of treatment and prevention. While there are many conferences on obesity and its associated co-morbidities, few take such an integrative approach bringing together such topics in a vertically integrated format. In order to develop effective methods of prevention and treatment for obesity and its associated co-morbidities it is incumbent that we understand all aspects of the contributing factors, and their interactions, to the development of obesity. Therefore, the objective of the proposed conference is to provide an opportunity for researchers working on the various facets of obesity to interact and initiate a dialogue in an effort to encourage increased interaction and collaboration from a more integrated perspective.
PROGRAM NARRATIVE: Among the adult population of the US it is now estimated that over 60 percent are overweight or obese, and the prevalence of childhood obesity is increasing at a staggering rate. The Department of Health and Human Services has ranked obesity among the most significant public health threats/burdens of the twenty-first century. To date efforts at prevention and treatment for obesity have met with mixed success, undoubtedly reflecting the underlying heterogeneity in its origin and expression. Therefore, given the multitude of factors impacting body weight regulation, patterns of lipid deposition, and adipose tissue function and their impact on metabolic and disease processes, it is critical for the field of obesity research t seek an integrative perspective in order to better understand the intricate interplay between genetics, behavior, and the external environment in order to identify the most productive avenues of treatment and prevention. While there are many conferences on obesity and its associated co-morbidities, few take such an integrative approach bringing together such topics in a vertically integrated format. In order to develop effective methods of prevention and treatment for obesity and its associated co-morbidities it is incumbent that we understand all aspects of the contributing factors, and their interactions, to the development of obesity. Therefore, the objective of the proposed conference is to provide an opportunity for researchers working on the various facets of obesity to interact and initiate a dialogue in an effort to encourage increased interaction and collaboration from a more integrated perspective.
描述(由申请人提供):在美国的成年人口中,目前估计有超过60%的人超重或肥胖,儿童肥胖的患病率正以惊人的速度增长。美国卫生与公众服务部将肥胖列为21世纪最严重的公共卫生威胁/负担之一。迄今为止,预防和治疗肥胖的努力取得了不同程度的成功,这无疑反映了其起源和表达的潜在异质性。因此,考虑到影响体重调节、脂质沉积模式和脂肪组织功能以及它们对代谢和疾病过程的影响的众多因素,它是关键的
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Anthony G. Comuzzie其他文献
ENTENDIENDO LAS CAUSAS DE LA OBESIDAD A TRAVÉS DE LA BIOLOGÍA CELULAR DEL ADIPOCITO. Revisión
ENTENDIENDO LAS CAUSAS DE LA OBESIDAD A TRAVÉS DE LA BIOLOGÍA CELULAR DEL ADIPOCITO。
- DOI:
- 发表时间:
2005 - 期刊:
- 影响因子:0
- 作者:
Raul A. Bastarrachea;Ramón E. Fuenmayor;I. Brajkovich;Anthony G. Comuzzie - 通讯作者:
Anthony G. Comuzzie
Heritability of Ambulatory and Beat-to-Beat Office Blood Pressure in Large Multigenerational Arab Pedigrees: The ‘Oman Family Study’
大型多代阿拉伯谱系中动态血压和逐次搏动办公室血压的遗传性:“阿曼家庭研究”
- DOI:
10.1017/thg.2012.59 - 发表时间:
2012 - 期刊:
- 影响因子:0.9
- 作者:
S. Albarwani;M. Munoz;V. S. Voruganti;D. Jaju;V. Saeed Al;S. Rizvi;J. López;Zahir M Al;R. Bayoumi;Anthony G. Comuzzie;H. Snieder;M. Hassan - 通讯作者:
M. Hassan
Genómica de la regulación del peso corporal: mecanismos moleculares que predisponen a la obesidad
Genómica de la regulación del peso corporal: mecanismos moleculares que predisponen a la obesidad
- DOI:
- 发表时间:
2004 - 期刊:
- 影响因子:0
- 作者:
Raul A. Bastarrachea;Shelley A. Cole;Anthony G. Comuzzie - 通讯作者:
Anthony G. Comuzzie
A Family Study in Oman: Large, Consanguineous, Polygamous Omani Arab Pedigrees
阿曼的家庭研究:庞大、近亲、一夫多妻制的阿曼阿拉伯血统
- DOI:
- 发表时间:
2005 - 期刊:
- 影响因子:1.7
- 作者:
M. Hassan;S. Albarwani;S. A. Yahyaee;S. A. Haddabi;S. Rizwi;A. Jaffer;J. Al;G. Cai;Anthony G. Comuzzie;R. Bayoumi - 通讯作者:
R. Bayoumi
Hemodynamic and Autonomic Reactivity to Mental and Physical Stress in Lean, Overweight and Obese Subjects
瘦、超重和肥胖受试者对精神和身体压力的血流动力学和自主反应
- DOI:
10.15744/2455-7633.2.105 - 发表时间:
2016 - 期刊:
- 影响因子:2.7
- 作者:
D. Jaju;M. Alabri;Hassan Mo;Alvarenga Jl;Anthony G. Comuzzie;S. Albarwani;S. AlYahyee;R. Bayoumi;K. Alhashmi - 通讯作者:
K. Alhashmi
Anthony G. Comuzzie的其他文献
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{{ truncateString('Anthony G. Comuzzie', 18)}}的其他基金
IDENTIFYING GENES FOR OBESITY QTLS RELATED TO CVD
识别与 CVD 相关的肥胖 QTLS 基因
- 批准号:
8357655 - 财政年份:2011
- 资助金额:
$ 1.8万 - 项目类别:
IDENTIFYING GENES FOR OBESITY QTLS RELATED TO CVD
识别与 CVD 相关的肥胖 QTLS 基因
- 批准号:
8172661 - 财政年份:2010
- 资助金额:
$ 1.8万 - 项目类别:
Identifying Genes for Obesity QTLs Related to CVD
识别与 CVD 相关的肥胖 QTL 基因
- 批准号:
8147442 - 财政年份:2010
- 资助金额:
$ 1.8万 - 项目类别:
CHARACTERIZATION OF NHPS DISPLAYING PHENOTYPES OF HUMAN DISEASES
显示人类疾病表型的 NHPS 特征
- 批准号:
7957962 - 财政年份:2009
- 资助金额:
$ 1.8万 - 项目类别:
BASAL HEPATIC GLUCOSE AND INSULIN SENSITIVITY IN BABOONS
狒狒的基础肝葡萄糖和胰岛素敏感性
- 批准号:
7562448 - 财政年份:2007
- 资助金额:
$ 1.8万 - 项目类别:
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