FASEB SRC on From Causes to Consequences, to Treatment: Obesity in Perspective

FASEB SRC 探讨从原因到后果，再到治疗：肥胖的视角

• 批准号: 8400279
• 负责人: Anthony G. Comuzzie
• 金额: $ 1.8万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-15 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8400279
• 关键词: Academia; Address; Adipose tissue; Adult; Area; Basic Science; Behavior; Behavioral Genetics; Biological Factors; Body Weight; Clinical; Collaborations; Communities; Comorbidity; Complex; Deposition; Development; Environment; Environmental Risk Factor; Fostering; Genes; Heterogeneity; Individual; Industry; Investigation; Lead; Life Style; Lipids; Metabolic Diseases; Methods; Nature; Obesity; Overweight; Pattern; Physiology; Population; Prevalence; Prevention; Prevention program; Preventive; Process; Public Health; Public Policy; Regulation; Research; Research Design; Research Personnel; Risk; Scientist; Shapes; United States Dept. of Health and Human Services; Work; base; career development; design; effective therapy; falls; holistic approach; improved; meetings; obesity in children; obesity treatment; pre-clinical; success; symposium; treatment program

DESCRIPTION (provided by applicant): Among the adult population of the US it is now estimated that over 60 percent are overweight or obese, and the prevalence of childhood obesity is increasing at a staggering rate. The Department of Health and Human Services has ranked obesity among the most significant public health threats/burdens of the twenty-first century. To date efforts at prevention and treatment for obesity have met with mixed success, undoubtedly reflecting the underlying heterogeneity in its origin and expression. Therefore, given the multitude of factors impacting body weight regulation, patterns of lipid deposition, and adipose tissue function and their impact on metabolic and disease processes, it is critical for the field of obesity research to seek an integrative perspective in order to better understand the intricate interplay between genetics, behavior, and the external environment in order to identify the most productive avenues of treatment and prevention. While there are many conferences on obesity and its associated co-morbidities, few take such an integrative approach bringing together such topics in a vertically integrated format. In order to develop effective methods of prevention and treatment for obesity and its associated co-morbidities it is incumbent that we understand all aspects of the contributing factors, and their interactions, to the development of obesity. Therefore, the objective of the proposed conference is to provide an opportunity for researchers working on the various facets of obesity to interact and initiate a dialogue in an effort to encourage increased interaction and collaboration from a more integrated perspective. PROGRAM NARRATIVE: Among the adult population of the US it is now estimated that over 60 percent are overweight or obese, and the prevalence of childhood obesity is increasing at a staggering rate. The Department of Health and Human Services has ranked obesity among the most significant public health threats/burdens of the twenty-first century. To date efforts at prevention and treatment for obesity have met with mixed success, undoubtedly reflecting the underlying heterogeneity in its origin and expression. Therefore, given the multitude of factors impacting body weight regulation, patterns of lipid deposition, and adipose tissue function and their impact on metabolic and disease processes, it is critical for the field of obesity research t seek an integrative perspective in order to better understand the intricate interplay between genetics, behavior, and the external environment in order to identify the most productive avenues of treatment and prevention. While there are many conferences on obesity and its associated co-morbidities, few take such an integrative approach bringing together such topics in a vertically integrated format. In order to develop effective methods of prevention and treatment for obesity and its associated co-morbidities it is incumbent that we understand all aspects of the contributing factors, and their interactions, to the development of obesity. Therefore, the objective of the proposed conference is to provide an opportunity for researchers working on the various facets of obesity to interact and initiate a dialogue in an effort to encourage increased interaction and collaboration from a more integrated perspective.

描述（由申请人提供）：在美国的成年人口中，目前估计有超过60%的人超重或肥胖，儿童肥胖的患病率正以惊人的速度增长。美国卫生与公众服务部将肥胖列为21世纪最严重的公共卫生威胁/负担之一。迄今为止，预防和治疗肥胖的努力取得了不同程度的成功，这无疑反映了其起源和表达的潜在异质性。因此，考虑到影响体重调节、脂质沉积模式和脂肪组织功能以及它们对代谢和疾病过程的影响的众多因素，它是关键的