A Comparison of Manual VS. Mechanical Chiropractic Manipulation Methods

手动与手动的比较。

• 批准号: 8290077
• 负责人: MICHAEL J SCHNEIDER
• 金额: $ 24.71万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8290077
• 关键词: Adherence; Advertising; Back; Belief; Chiropractic manipulation; Clinical; Clinical Trials; Clinical effectiveness; Effectiveness; Enrollment; Exercise; Expectancy; Frequencies; Fright; Future; Literature; Location; Low Back Pain; Mails; Manuals; Mechanics; Mediator of activation protein; Medical; Methods; Minority; Modeling; Outcome; Outcome Measure; Pain; Participant; Patients; Pharmaceutical Preparations; Procedures; Questionnaires; Randomized; Recruitment Activity; Reporting; Research; Review Literature; Sample Size; Spinal; Spinal Manipulation; Visit; chiropracty; comparative effectiveness; cost effective; design; disability; effective therapy; expectation; follow-up; instrument; interest; primary outcome; randomized trial; research study; secondary outcome; success; systematic review; treatment effect

This Study will be a small randomized trial (n=40 per group) comparing the clinical effectiveness of mechanical instrument assisted manipulation (MIAM) with traditional manual thrust manipulation (MTM) for the treatment of low back pain (LBP). Systematic reviews of the literature have described at least 42 randomized trials using spinal manipulation as a treatment for LBP, the majority of which utilized some variety of MTM but no high quality studies utilizing MIAM. This trial mil explore the differences in clinical effectiveness of these two manipulative methods for LBP. Eighty patients with a new onset of LBP within the past 12 weeks will be recruited and randomized into two groups; treatment with MTM or treatment with MIAM. ITie treatment frequency will be twice per week for 4 weeks (8 visits in total). Outcome measures will be gathered at 4,12, and 24 weeks. The primary outcome measure will be the Oswestry Disability Questionnaire (ODQ) score at 4-weeks. The secondary outcome measure will be the Numeric Pain Rating Scale (NPRS). Other secondary variables of interest will include treatment expectancy for each type of manipulation, fear-avoidance beliefs score, and presence of predictor variables from previously validated clinical prediction rules associated with manipulation and stabilization exercise successes. The primary analysis will be a generalized Imear regression model with 6-week ODQ score as the dependent variable and treatment group as the key independent variable; while controlling for baseline randomization variables and treatment expectation scores as covariates in the model. The secondary analysis will be a shnilar regression model using NPRS score as the dependent variable. The key aims of this study are; (1) to acquire infonnation that will be used to design a large clinical trial (ROl) on the comparative effectiveness of different types of spinal manipxUation and to determine its feasibility, and (2) to obtain parameter estimates of effect sizes and explore potential confounders or treatment effect mediators for the future larger trial.

本研究将是一项小型随机试验（每组n=40），比较两种药物的临床疗效

项目成果

The association of biomarkers with pain and function in acute and subacute low back pain: a secondary analysis of an RCT.

• DOI: 10.1186/s12891-022-06027-9
• 发表时间: 2022-12-05
• 期刊: BMC MUSCULOSKELETAL DISORDERS
• 影响因子: 2.3
• 作者: Tonelli Enrico, Valerio;Schneider, Michael;Haas, Mitchell;Vo, Nam;Huang, Wan;McFarland, Christine;Weber, Nick;Sowa, Gwendolyn
• 通讯作者: Sowa, Gwendolyn