CTSA INFRASTRUCTURE FOR AIDS RESEARCH

CTSA 艾滋病研究基础设施

• 批准号: 8365028
• 负责人: THOMAS Arthur PEARSON
• 金额: $ 31.15万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365028
• 关键词: Acquired Immunodeficiency Syndrome; Clinical Sciences; Institutes; Research; Research Infrastructure; Translational Research; Universities

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. DESCRIPTION (provided by applicant): The Rochester Clinical and Translational Science Award (RCTSA) Program proposes continuation of its dual goals: 1) To organize, support, and expand clinical and translational research at the University of Rochester within an academic home, the University of Rochester Clinical and Translational Science Institute (UR-CTSI), and 2) To integrate and collaborate with regional and national institutions to expand a National Clinical and Translational Research Network. The RCTSA Program has truly transformed the University of Rochester Medical Center (URMC), with the construction of a state-of-the-art Clinical and Translational Science Building, the integration of clinical and translational science into the shared vision for URMC research, a successful system of dynamic governance, expansion of research resources, and enthusiastic participation and leadership in the National CTSA Consortium. To continue this momentum, the UR-CTSI will carry out a number of specific aims. First, three new key functions will be implemented: Public-Private Partnerships, T1 Translation, and Comparative Effectiveness Research. Existing Key Functions will be reorganized and consolidated to provide better support of investigators by an expanded Office of Regulatory Support, a Navigator/Consultation Service, and an Incubator Program consolidating Pilot Studies, Novel Methodologies, and Translational Technologies Key Functions. The CTSI will establish and foster four centers of research excellence across the spectrum of research translation: Center for Human Experimental Therapeutics (T1 Research); Clinical Research Center (T1-3 Research); Center for Research Implementation and Translation (T2-3 research under School of Nursing sponsorship); and Center for Community Health (T2-3 research). A broad range of education, training, and career development programs will continue to meet research workforce needs. The UR-CTSI will be an active participant in the National CTSA consortium with sharing of expertise, methods, data, and curricula. The Upstate New York Translational Research Network (UNYTRN) will be expanded to support the region's biomedical research institutions. Finally, the UR-CTSI will be evaluated through the measurement of rigorous performance outcomes. PUBLIC HEALTH RELEVANCE (provided by applicant): The UR Clinical and Translational Science Institute (UR-CTSI) will be the focal point for translation of basic discoveries to human applications and clinical trials, and for evidence-based implementation of efficacious clinical practices and effective community strategies. The UR-CTSI will be a model for CTSA involvement of nursing, dentistry, and other disciplines, for engagement of the Rochester community in all aspects of research and for collaboration with regional biomedical institutions in research translation.

该子项目是对CTSA供资的百分比的估计， 用于广泛的研究领域（艾滋病研究，儿科研究，或 临床试验）。 列出的总成本仅为CTSA金额的估算 基础设施走向这一领域的研究，而不是直接提供资金， 向子项目或子项目工作人员提供NCRR补助金。 描述（申请人提供）：罗切斯特临床和转化科学奖（RCTSA）项目提议继续其双重目标：1）组织，支持和扩大罗切斯特大学的临床和转化研究，在学术之家，罗切斯特大学临床和转化科学研究所（UR-CTSI），2）与区域和国家机构整合和合作，扩大国家临床和转化研究网络。RCTSA计划真正改变了罗切斯特医学中心（URMC）的大学，建设了最先进的临床和转化科学大楼，将临床和转化科学整合到URMC研究的共同愿景中，建立了成功的动态治理系统，扩大了研究资源，并热情参与和领导国家CTSA联盟。为了保持这一势头，UR-CTSI将实现一些具体目标。首先，将实施三个新的关键职能：公私合作伙伴关系、T1翻译和比较有效性研究。现有的关键职能将进行重组和整合，以通过扩大的监管支持办公室、导航/咨询服务和孵化器计划为研究者提供更好的支持，该孵化器计划整合了试点研究、新方法和转化技术关键职能。CTSI将在研究翻译领域建立和培养四个卓越的研究中心：人类实验治疗中心（T1研究）;临床研究中心（T1-3研究）;研究实施和翻译中心（护理学院赞助下的T2-3研究）;和社区健康中心（T2-3研究）。广泛的教育，培训和职业发展计划将继续满足研究人员的需求。UR-CTSI将积极参与国家CTSA联盟，分享专业知识，方法，数据和课程。将扩大纽约州北部转化研究网络，以支持该地区的生物医学研究机构。最后，将通过衡量严格的业绩成果来评价UR-CTSI。 公共卫生相关性（由申请人提供）：UR临床和转化科学研究所（UR-CTSI）将成为将基本发现转化为人类应用和临床试验的协调中心，并以证据为基础实施有效的临床实践和有效的社区战略。UR-CTSI将成为CTSA参与护理，牙科和其他学科的典范，罗切斯特社区参与研究的各个方面，并与区域生物医学机构合作进行研究翻译。