Biostatistics Core

本计划项目赠款的生物统计核心负责开发和执行所需的大小规模统计分析，以满足本计划项目赠款中每个单独项目的目标。这涉及到： (1)为每个项目选择适当的技术方法和软件，并在必要时开发与实施所选方法有关的其他软件。在某些情况下，这还可能包括开发新的统计方法 (2)为方案项目申请中的每个项目设计和开发分析文件。这包括协助从多民族群组生物资料库中挑选样本进行分析，以便在项目1-4中进行研究，并参与质量控制数据的设计和分析，以确定所有项目中与吸烟有关的生物标志物的实验室差异和人与人之间的差异(3)利用(2)中的分析文件对每个项目进行和/或指导数据分析。

The Biostatistics Core forthis program project grant is responsible for developing and performing the large and small scale statistical analysis required for meefing the aims of each ofthe individual projects in thisprogram project grant. This involves: (1) Choosing appropriate stafistical methods and software for each project and when necessary developingadditional software relating to the implementation of the selected methods. In some cases this may also include development of new statistical methods (2) Designing and developing analysis files for each of the projects in the program project application. This includes assisting in the selecfion of samples for analysis from the Multiethnic Cohort (MEC)biorepository for study in Projects 1 - 4 , and participating in the design and analysis of quality controldata to determine laboratory variation, and between and within person-variation in the smoking-related biomarkers of concern in all projects(3) Performing and/or guiding data analysis for each project using the analysis files from (2).