Biostatistics Core

生物统计学核心

• 批准号: 8637009
• 负责人: Daniel O Stram
• 金额: $ 22.57万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8637009
• 关键词: Biological Markers; Biostatistics Core; Computer software; Data; Data Analyses; Development; Disease; Epidemiologic Studies; Grant; Individual; Laboratories; Malignant neoplasm of lung; Methods; Persons; Program Research Project Grants; Quality Control; Sampling; Services; Smoking; Statistical Methods; Variant; biobank; cigarette smoking; cohort; design; meetings; programs; racial/ethnic difference

The Biostatistics Core for this program project grant is responsible for developing and performing the large and small scale statistical analysis required for meeting the aims of each of the individual projects in this program project grant. This involves: (1) Choosing appropriate statistical methods and software for each project and when necessary developing additional software relating to the implementation of the selected methods. In some cases this may also include development of new statistical methods (2) Designing and developing analysis files for each of the projects in the program project application. This includes assisting in the selection of samples for analysis from the Multiethnic Cohort (MEC) biorepository for study in Projects 1 - 4 , and participating in the design and analysis of quality control data to determine laboratory variation, and between and within person-variation in the smoking-related biomarkers of concern in all projects(3) Performing and/or guiding data analysis for each project using the analysis files from (2).

该计划项目赠款的生物统计核心负责开发和执行所需的大小规模统计分析，以满足该计划项目赠款中每个单独项目的目标。这涉及到： (1)为每个项目选择适当的统计方法和软件，并在必要时开发与实施所选方法有关的额外软件。在某些情况下，这还可能包括开发新的统计方法 (2)为方案项目申请中的每个项目设计和开发分析文件。这包括协助从多民族群组生物资料库中挑选样本进行分析，以供项目1-4研究，并参与质量控制数据的设计和分析，以确定所有项目中与吸烟有关的生物标记物的实验室变异、人与人之间和人内变异(3)利用(2)中的分析文件对每个项目进行和/或指导数据分析。