Roles of DNA Ligase 1 in Mammalian DNA Metabolism

DNA 连接酶 1 在哺乳动物 DNA 代谢中的作用

• 批准号: 8366487
• 负责人: Alan E Tomkinson
• 金额: $ 15.83万
• 依托单位: UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8366487
• 关键词: Address; Biochemical; Biological; Biological Assay; Cell Cycle Checkpoint; Cell Cycle Stage; Cell Proliferation; Cell Survival; Cell physiology; Cells; Characteristics; Complex; Cytostatics; DNA; DNA Damage; DNA Ligases; DNA Repair; DNA Repair Pathway; DNA biosynthesis; DNA ligase I; Enzymes; Excision Repair; Genes; Genetic; Genome Stability; Genomic Instability; Goals; Health; Human; In Vitro; Laboratories; Ligation; Malignant Neoplasms; Mass Spectrum Analysis; Metabolism; Molecular; Normal Cell; Okazaki fragments; Pathway interactions; Phosphorylation; Phosphorylation Site; Play; Post-Translational Protein Processing; Process; Progress Reports; Proteins; Reaction; Resolution; Role; Slide; Specificity; Structure; Testing; Therapeutic; Tumor Suppression; base; cancer cell; clinical application; cytotoxic; human DNA; in vivo; inhibitor/antagonist; insight; neoplastic cell; novel; protein protein interaction; public health relevance; recombinational repair; repaired; small molecule