MAINTENANCE AND MONITORING OF RHESUS MONKEYS WITH TYPE-2 DIABETES

患有 2 型糖尿病的恒河猴的维护和监测

• 批准号: 8357303
• 负责人: PETER J HAVEL
• 金额: $ 7.56万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357303
• 关键词: Animals; Blood Glucose; Blood specimen; Body Weight; California; Clinical; Consumption; Diabetes Mellitus; Fructose; Funding; Future; Grant; Insulin; Macaca mulatta; Maintenance; Monitor; National Center for Research Resources; Non-Insulin-Dependent Diabetes Mellitus; Pharmaceutical Preparations; Primates; Principal Investigator; Research; Research Infrastructure; Resources; Sampling; Source; Subcutaneous Injections; United States National Institutes of Health; cost; diabetic; pre-clinical research; research study; sugar; sweetened beverage

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Genentech was supporting the maintenance and treatment of a number of diabetic rhesus monkeys at the CNPRC. The animals may be used to provide research samples for analysis or future preclinical research studies. Animals with spontaneously occurring diabetes or animals that have developed diabetes during prolonged consumption of sugar (fructose) sweetened beverages are being maintained. Blood samples are drawn for clinical monitoring, and medications (insulin) is administered by subcutaneous injection to stabilize body weight and blood glucose levels.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 子项目的主要研究者可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 基因技术公司在CNPRC支持维持和治疗一些患糖尿病的恒河猴。动物可用于提供研究样本，用于分析或未来的临床前研究。正在饲养自发发生糖尿病的动物或在长期食用含糖（果糖）的饮料期间发生糖尿病的动物。 抽取血液样品用于临床监测，并通过皮下注射施用药物（胰岛素）以稳定体重， 血糖水平