ID OF SNPS FOR ADMIXTURE MAPPING OF A QTL FOR TEMPERAMENT IN RHESUS MACAQUES

恒河猴气质 QTL 混合作图的 SNPS ID

• 批准号: 8357295
• 负责人: DAVID Glenn SMITH
• 金额: $ 5.04万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357295
• 关键词: Admixture; Animals; California; Chinese People; Chromosomes; Frequencies; Funding; Genes; Genome; Genotype; Grant; Hybrids; Location; Macaca mulatta; Maps; Measures; Methodology; National Center for Research Resources; Primates; Principal Investigator; Quantitative Trait Loci; Research; Research Infrastructure; Resources; Single Nucleotide Polymorphism; Source; Temperament; United States National Institutes of Health; cost

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The objective of this study is to identify a sufficient number of ancestry informative markers (AIMS; single nucleotide polymorphisms, or SNPS, that maximally differ in frequency between Indian and Chinese rhesus macaques) and genotype them in Indian/Chinese hybrid rhesus macaques of varying proportions of ancestry(between ¿ and ¿ Chinese ancestry) for which measures of "temperament" have been quantified in a previous study. By comparing SNP frequencies of hybrid animals with "low" versus "high" temperament across all chromosomes, an attempt will be made to identify locations of genes in the rhesus genome that influence "temperament," a methodology of whole genome association called "admixture mapping."

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