GENETIC MANAGEMENT OF ANIMAL COLONIES

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 该项目的目标是1)确定单核苷酸多态(SNPs)，用于从遗传学角度表征猕猴和长尾猕猴区域种群内部和之间的遗传差异；2)确定一组对遗传管理最有用的SNP；以及3)基于UCD基因组中心对SNP小组的高通量基因分型，为NIH研究人员提供基因分型和遗传管理服务。该项目还将确定一个高度多态的SNPs的扩大小组，用于全基因组关联研究，以检测特定疾病和表型的候选基因。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objectives of this project are to 1) identify single nucleotide polymorphisms (SNPs) useful to genetically characterize genetic differences within and among regional populations of rhesus and longtail macaques, 2) identify a panel of SNPs most useful for genetic management, and 3) provide genotyping and genetic management services to NIH investigators based on high throughput genotyping of the SNP panel using the UCD Genome Center. This project will also identify an expanded panel of highly polymorphic SNPs for use in whole genome association studies to detect candidate genes for specific diseases and phenotypes.