GENETIC MANAGEMENT OF ANIMAL COLONIES

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 中心，不一定是研究者的机构。 该项目的目标是1）确定单核苷酸多态性（SNPs）有用的遗传特性内和恒河猴和长尾猕猴的区域种群之间的遗传差异，2）确定最有用的SNPs的面板遗传管理，和3）提供基因分型和遗传管理服务，以NIH研究人员基于高通量的SNP面板基因分型使用UCD基因组中心。该项目还将确定一个扩展的高度多态性SNP组，用于全基因组关联研究，以检测特定疾病和表型的候选基因。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objectives of this project are to 1) identify single nucleotide polymorphisms (SNPs) useful to genetically characterize genetic differences within and among regional populations of rhesus and longtail macaques, 2) identify a panel of SNPs most useful for genetic management, and 3) provide genotyping and genetic management services to NIH investigators based on high throughput genotyping of the SNP panel using the UCD Genome Center. This project will also identify an expanded panel of highly polymorphic SNPs for use in whole genome association studies to detect candidate genes for specific diseases and phenotypes.