DIFFUSE OPTICS FOR ACUTE STROKE MANAGEMENT

用于急性中风治疗的漫射光学器件

• 批准号: 8361985
• 负责人: ARJUN G. YODH
• 金额: $ 0.77万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361985
• 关键词: Cerebrovascular Circulation; Cerebrum; Collaborations; Core-Binding Factor; Diffuse; Funding; Grant; Magnetic Resonance; Magnetic Resonance Imaging; Measurement; Metabolic; Metabolism; Monitor; National Center for Research Resources; Optics; Patients; Principal Investigator; Research; Research Infrastructure; Resources; Source; Spectrum Analysis; United States National Institutes of Health; acute stroke; base; cost; optical imaging

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. This R01 project seeks to develop optical monitoring of cerebral blood flow and metabolism for use as a bedside monitor for individualized treatment of patients with acute stroke. This project includes a collaboration between TRD2 and TRD4 in the use of ASL MRI to validate optical CBF measurements based on diffuse correlation spectroscopy as well as with TRD1 to validate optical measurements of cerebral metabolic rate with 17O-MRI.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 该R 01项目旨在开发脑血流和代谢的光学监测， 用于急性卒中患者个体化治疗的床旁监护仪。 该项目包括一个 TRD 2和TRD 4在使用ASL MRI确认光学CBF测量方面的合作 基于扩散相关光谱以及TRD 1，以验证 脑代谢率的17 O-MRI。