SPINAL CORD ASTROCYTES AND CHRONIC PAIN

脊髓星形细胞和慢性疼痛

• 批准号: 8361931
• 负责人: Ken Douglas McCarthy
• 金额: $ 2.47万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361931
• 关键词: Astrocytes; Cells; Complement; Electrons; Fluorescent Dyes; Funding; Grant; Image Analysis; Light; Measurement; Microscopic; Morphology; National Center for Research Resources; Principal Investigator; Research; Research Infrastructure; Resources; Source; Spinal; Spinal Cord; United States National Institutes of Health; chronic pain; cost; electron tomography

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We are studying the consequences of chronic pain on astrocytes in the spinal cord. In order to complement electrophysiological measurements being made on spinal astrocytes, we would like to examine changes in the morphology of astrocytes at the light and electron microscopic levels. We would like to approach this with a combination of fluorescent dye cell fills, photoconversion, and electron tomography.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 我们正在研究慢性疼痛对脊髓中星形胶质细胞的后果。为了补充脊柱星形胶质细胞进行的电生理测量，我们想检查在光和电子显微镜水平下星形胶质细胞形态的变化。我们想通过荧光染料细胞填充，光转换和电子断层扫描的结合来处理此问题。