SPINAL CORD ASTROCYTES AND CHRONIC PAIN

脊髓星形细胞和慢性疼痛

• 批准号: 8361931
• 负责人: Ken Douglas McCarthy
• 金额: $ 2.47万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361931
• 关键词: Astrocytes; Cells; Complement; Electrons; Fluorescent Dyes; Funding; Grant; Image Analysis; Light; Measurement; Microscopic; Morphology; National Center for Research Resources; Principal Investigator; Research; Research Infrastructure; Resources; Source; Spinal; Spinal Cord; United States National Institutes of Health; chronic pain; cost; electron tomography

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We are studying the consequences of chronic pain on astrocytes in the spinal cord. In order to complement electrophysiological measurements being made on spinal astrocytes, we would like to examine changes in the morphology of astrocytes at the light and electron microscopic levels. We would like to approach this with a combination of fluorescent dye cell fills, photoconversion, and electron tomography.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 我们正在研究慢性疼痛对脊髓星形胶质细胞的影响。为了补充对脊髓星形胶质细胞的电生理测量，我们想在光镜和电镜水平上研究星形胶质细胞形态的变化。我们希望通过荧光染料电池填充、光转换和电子断层扫描的组合来实现这一点。