ESTIMATION OF CBF VALUES USING MULTI-ECHO DSC-MRI: A COMPARISON WITH A XENON CT

使用多回波 DSC-MRI 估算 CBF 值：与氙气 CT 的比较

• 批准号: 8362917
• 负责人: MATUS STRAKA
• 金额: $ 1.95万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362917
• 关键词: Annual Reports; Blood Vessels; Bolus Infusion; Clip; Complement; Core-Binding Factor; Data; Funding; Grant; Magnetic Resonance; Magnetic Resonance Imaging; Morphologic artifacts; National Center for Research Resources; Noise; Perfusion; Predisposition; Principal Investigator; Process; Reading; Research; Research Infrastructure; Resources; Scanning; Signal Transduction; Source; Technology; Tissues; Tracer; United States National Institutes of Health; Visit; Xenon; abstracting; cost

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Spatial distortions in EPI sequences and clipping of vascular signals during bolus passage peak a scanning sequence for perfusion with multiple echoes and temporal enhancement (PERMEATE) was developed, in which the confounding artifacts should be reduced. Data acquired with first (short) echo should be used to properly recover the vascular signals, whereas the later echoes are used to determine signals in the tissue manifesting better signal-to-noise ratio therein. Such state-of- the-art perfusion acquisition is complemented by a PWI post-processing pipeline, including correction for partialvolume effect (PVE) in vascular signals and susceptibility effect of the paramagnetic tracer in large vessels. To read about other projects ongoing at the Lucas Center, please visit http://rsl.stanford.edu/ (Lucas Annual Report and ISMRM 2011 Abstracts)

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 EPI序列中的空间失真和团注通过期间血管信号的剪裁 建立了多回声和时间增强(渗透性)的灌注成像，其中混杂伪影 应该减少。使用第一次(短)回波获取的数据应用于正确恢复血管信号，而 后一回波被用来确定组织中表现出较好信噪比的信号。这样的状态- 先进的血流灌注采集由PWI后处理管道补充，包括对部分体积的校正 大血管中顺磁示踪剂对血管信号的影响(PVE)和敏感性效应。 要了解卢卡斯中心正在进行的其他项目，请访问http://rsl.stanford.edu/(卢卡斯年度报告和 ISMRM 2011年摘要)