GLYCOVAULT: A BIOINFORMATICS INFRASTRUCTURE FOR GLYCAN PATHWAY ANALYSIS

GLYCOVAULT：用于聚糖通路分析的生物信息学基础设施

• 批准号: 8363024
• 负责人: WILLIAM YORK
• 金额: $ 4.13万
• 依托单位: UNIVERSITY OF GEORGIA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8363024
• 关键词: Anabolism; Bioinformatics; Cells; Data; Data Analyses; Enzymes; Funding; Gene Expression; Grant; Imagery; Knowledge; Life Cycle Stages; Modeling; National Center for Research Resources; Ontology; Pathway Analysis; Pathway interactions; Polysaccharides; Principal Investigator; Process; Proteins; Research; Research Infrastructure; Research Support; Resources; Source; Technology; United States National Institutes of Health; cost; information organization; programs; relational database

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The principal purpose of Glyco-Vault is to support the research of glycobiologists in collecting and analyzing data about glycans, such as the changes in their abundance level over a cell's life cycle as well as their correlation with gene expression levels for proteins that serve as enzymes in the biosynthetic process. In order to support glycan biosynthesis pathway visualization, analysis and modeling, GlycoVault has been collecting data and knowledge from a variety of sources. Traditional, bioinformatics resources have been provided by relational databases, although representation of this knowledge using ontologies has its own advantages. In GlycoVault, we utilize both technologies to supply an integrated bioinformatics infrastructure that can serve as a resource to both end users as well as other programs and applications.

这个子项目是利用这些资源的众多研究子项目之一