STRUCTURE OF A C-TERMINAL PEPTIDE OF TRPV1 BOUND TO CALMODULIN

与钙调蛋白结合的 TRPV1 C 端肽的结构

• 批准号: 8361629
• 负责人: RACHELLE GAUDET
• 金额: $ 0.68万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361629
• 关键词: Binding; C-terminal; Calcium; Calmodulin; Funding; Grant; Ion Channel; National Center for Research Resources; Peptides; Principal Investigator; Research; Research Infrastructure; Resources; Source; Structure; Temperature; United States National Institutes of Health; Vanilloid; cost; desensitization; inhibitor/antagonist; interest; receptor; structural biology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We are interested in the interaction of calmodulin with the Transient receptor potential vanilloid 1 (TRPV1) ion channel. Calcium and calmodulin are important inhibitors of TRPV1, causing desensitization and regulating the sensitivity of TRPV1 to temperature.

这个子项目是利用这些资源的众多研究子项目之一