STRUCTURE OF A BACTERIAL NRAMP TRANSPORTER
STRUCTURE OF A BACTERIAL NRAMP TRANSPORTER
批准号:
8361710
负责人:
RACHELLE GAUDET
金额:
$0.68万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-04-01 至 2012-03-31
中文摘要
这个子项目是许多利用资源的研究子项目之一
由NIH/NCRR资助的中心拨款提供。次级项目的主要支助
而子项目的主要调查员可能是由其他来源提供的,
包括其它NIH来源。 列出的子项目总成本可能
表示子项目使用的中心基础设施的估计数量,
NCRR赠款不直接向子项目或子项目工作人员提供资金。
二价金属如铁和锰是许多生物化学过程所必需的。 细胞二价金属稳态需要专门的跨膜转运蛋白。 我们的目标是确定细菌NRAMP转运蛋白的原子结构,作为理解NRAMP转运蛋白如何使用质子梯度选择和转运二价阳离子的一个步骤。
英文摘要
This subproject is one of many research subprojects utilizing the resources
provided by a Center grant funded by NIH/NCRR. Primary support for the subproject
and the subproject's principal investigator may have been provided by other sources,
including other NIH sources. The Total Cost listed for the subproject likely
represents the estimated amount of Center infrastructure utilized by the subproject,
not direct funding provided by the NCRR grant to the subproject or subproject staff.
Divalent metals such as iron and manganese are essential to may biochemical processes. Cellular divalent metal homeostasis requires specialized transmembrane transporters. We aim to determine the atomic structure of a bacterial NRAMP transporter as a step in understanding how NRAMP transporters select and transport divalent cations using a proton gradient.
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资助金额:$0.35万
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依托单位:
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依托单位:
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依托单位:
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资助金额:$0.81万
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负责人:RACHELLE GAUDET
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