PROTEOMICS REVEALS RAPIDLY EVOLVING POLLEN TUBE PROTEINS

蛋白质组学揭示快速进化的花粉管蛋白质

• 批准号: 8365839
• 负责人: WILLIE J SWANSON
• 金额: $ 0.65万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365839
• 关键词: Biology; Candidate Disease Gene; Diatoms; Drosophila genus; Evolution; Fertility; Funding; Fungal Genome; Genes; Goals; Grant; Human; Mammals; National Center for Research Resources; Organism; Pollen Tube; Principal Investigator; Proteins; Proteomics; Research; Research Infrastructure; Resources; Source; United States National Institutes of Health; Work; abalone; cost; egg; reproductive; sperm cell

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. A recurring observation in the study of reproductive proteins is their rapid, adaptive evolution. This phenomenon occurs in organisms as diverse as diatoms and humans. The long-term goal of our research is to understand the diversity of reproductive proteins and the functional consequences of their divergence, which could involve problems in fertility and speciation due to a mismatch of sperm-egg recognition molecules. We work with a variety of organisms, including Drosophila, abalone (Haliotis), and mammals. A common theme throughout our research is identifying genes subjected to positive selection (adaptive evolution), indicating potentially functionally important candidate genes.

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