2012 Chemotactic Cytokines Gordon Research Conference & Gordon Research Seminar

2012年趋化细胞因子戈登研究会议

• 批准号: 8307657
• 负责人: ANDREW D LUSTER
• 金额: $ 0.7万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-03-01 至 2013-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8307657
• 关键词: Affect; Age; Age-Years; American; Area; Autoimmune Diseases; Autoimmunity; Biochemical; Biological; Brain; Cell Communication; Cells; Chemotactic Factors; Clinic; Clinical Research; Collaborations; Communicable Diseases; Complex; Country; Cytokine Gene; Development; Discipline; Disease; Embryonic Development; Emigrations; Ensure; Environment; Europe; Feedback; Fees; Fertilization; Fostering; Future; Future Generations; Gene Family; Generations; Goals; Growth; Health; Host Defense; Human; Human Genome; Immune; Inflammation; Inflammatory; Intervention; Journals; Leukocytes; Link; Malignant Neoplasms; Medical; Mentors; Molecular; Neoplasm Metastasis; Oral; Organ; Participant; Pathogenesis; Pathologic Processes; Pathology; Pathway interactions; Physiological Processes; Play; Postdoctoral Fellow; Recording of previous events; Request for Applications; Research; Research Personnel; Research Project Grants; Role; Scientist; Seasons; Senior Scientist; Series; Signal Transduction; Social Interaction; Specialist; Therapeutic; Thinking; Time; Tissues; Translations; Travel; United States National Institutes of Health; Work; abstracting; age group; base; cell type; chemokine; chemokine receptor; empowered; experience; graduate student; human disease; innovation; intercellular communication; medical specialties; meetings; migration; novel; novel strategies; peer; planetary Atmosphere; posters; professor; programs; receptor; research study; symposium; therapeutic target; tumor

DESCRIPTION (provided by applicant): Chemokines, the structurally homologous, functionally distinct chemotactic cytokines together with their cognate classical and atypical receptors comprise a complex molecular network involved in nearly all aspects of human health and disease. The Gordon Research Conference (GRC) on Chemotactic Cytokines 2012 is a world premier meeting devoted entirely to understanding these important molecules. This will be our 10th Chemokine GRC, which has been held every other year since 1994, when chemokines first burst onto the scene as the largest cytokine gene family in the human genome. Similar to each preceding conference in this series, Chemokine GRC 2012 will bring together scientists from a broad range of biomedical disciplines to showcase the latest unpublished research findings that cover all aspects of chemokine function and provide a high-quality scientific forum to discuss their potential implications, including translation to the clinic. The program of this meeting will cover basic biochemical and biological aspects of chemokines as related to their contributions to leukocyte migration, emigration, immune tissue organization and function; the role of chemokines during inflammation, including infectious diseases and autoimmunity in distinct organs and tissues; and multifaceted contributions of chemokines to cancer pathogenesis. In addition, for the first time in the history of this conference, we will introduce he Gordon Research Seminars (GRS), a satellite meeting for bench scientists at the graduate and postdoctoral level. GRS will provide a forum where young researchers can present their work and receive feedback on their ongoing research projects from their peers and a selected panel of senior experts. GRS will promote grassroots level integration and networking within the field of chemokine research. We fully anticipate that the scientific discussions, research talks, poster sessions, and informal interactions between the participants of this conference will contribute to advancing our understanding of molecular mechanisms of chemokine involvement in disease pathogenesis. This will set the basis for the development of new collaborative projects leading to new discoveries and ultimately resulting in new therapies and approaches to treat debilitating human disease, including inflammatory and autoimmune diseases and cancer. PUBLIC HEALTH RELEVANCE: The Gordon Research Conference on Chemotactic Cytokines and the Gordon Research Seminar will bring together chemokine scientists from a variety of biomedical disciplines at all levels of this endeavor, including established investigators, junior investigators, and future generations of chemokine researchers. Scientific presentations, discussions and poster sessions during this conference will expand our understanding of the mechanisms by which chemokines contribute to health and disease. It is anticipated that the collegial and cooperative atmosphere that has traditionally characterized these conferences will provide the perfect setting for the intellectual development, cross-fertilization and future collaborations that are so vital to keep this field at the forefront of scientific innovation and discovery.

描述（由申请人提供）：趋化因子是结构同源、功能不同的趋化性细胞因子，与其同源的经典和非典型受体一起构成复杂的分子网络，涉及人类健康和疾病的几乎所有方面。2012年戈登趋化性细胞因子研究会议（GRC）是一个世界顶级会议，完全致力于了解这些重要分子。这将是我们的第10届趋化因子GRC，自1994年以来每隔一年举行一次，当时趋化因子首次作为人类基因组中最大的细胞因子基因家族出现。与本系列之前的每一次会议类似，Chemokine GRC 2012将汇集来自广泛生物医学学科的科学家，展示最新的未发表的研究成果，涵盖趋化因子功能的各个方面，并提供高质量的科学论坛，讨论其潜在的影响，包括翻译到临床。本次会议的计划将涵盖趋化因子的基本生物化学和生物学方面，涉及其对白细胞迁移，迁出，免疫组织组织和功能的贡献;趋化因子在炎症过程中的作用，包括感染性疾病和不同器官和组织中的自身免疫;以及趋化因子对癌症发病机制的多方面贡献。此外，在本次会议的历史上，我们将首次介绍他戈登研究研讨会（GRS），在研究生和博士后水平的实验室科学家的卫星会议。GRS将提供一个论坛，让年轻研究人员可以介绍他们的工作，并从同行和选定的高级专家小组那里获得关于他们正在进行的研究项目的反馈。GRS将促进趋化因子研究领域的基层整合和网络化。我们充分期待本次会议参与者之间的科学讨论，研究讲座，海报会议和非正式互动将有助于促进我们对趋化因子参与疾病发病机制的分子机制的理解。这将为开发新的合作项目奠定基础，从而带来新的发现，并最终产生新的疗法和方法来治疗使人衰弱的疾病，包括炎症和自身免疫性疾病和癌症。 公共卫生关系：戈登趋化性细胞因子研究会议和戈登研究研讨会将汇集来自各种生物医学学科的趋化因子科学家，包括已建立的研究人员，初级研究人员和未来几代趋化因子研究人员。本次会议期间的科学报告，讨论和海报会议将扩大我们对趋化因子促进健康和疾病的机制的理解。预计这些会议传统上特有的合议和合作气氛将为智力发展，交叉施肥和未来合作提供完美的环境，这些合作对于保持该领域处于科学创新和发现的前沿至关重要。