2012 Chemotactic Cytokines Gordon Research Conference & Gordon Research Seminar

2012年趋化细胞因子戈登研究会议

• 批准号: 8307657
• 负责人: ANDREW D LUSTER
• 金额: $ 0.7万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-03-01 至 2013-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8307657
• 关键词: Affect; Age; Age-Years; American; Area; Autoimmune Diseases; Autoimmunity; Biochemical; Biological; Brain; Cell Communication; Cells; Chemotactic Factors; Clinic; Clinical Research; Collaborations; Communicable Diseases; Complex; Country; Cytokine Gene; Development; Discipline; Disease; Embryonic Development; Emigrations; Ensure; Environment; Europe; Feedback; Fees; Fertilization; Fostering; Future; Future Generations; Gene Family; Generations; Goals; Growth; Health; Host Defense; Human; Human Genome; Immune; Inflammation; Inflammatory; Intervention; Journals; Leukocytes; Link; Malignant Neoplasms; Medical; Mentors; Molecular; Neoplasm Metastasis; Oral; Organ; Participant; Pathogenesis; Pathologic Processes; Pathology; Pathway interactions; Physiological Processes; Play; Postdoctoral Fellow; Recording of previous events; Request for Applications; Research; Research Personnel; Research Project Grants; Role; Scientist; Seasons; Senior Scientist; Series; Signal Transduction; Social Interaction; Specialist; Therapeutic; Thinking; Time; Tissues; Translations; Travel; United States National Institutes of Health; Work; abstracting; age group; base; cell type; chemokine; chemokine receptor; empowered; experience; graduate student; human disease; innovation; intercellular communication; medical specialties; meetings; migration; novel; novel strategies; peer; planetary Atmosphere; posters; professor; programs; receptor; research study; symposium; therapeutic target; tumor

DESCRIPTION (provided by applicant): Chemokines, the structurally homologous, functionally distinct chemotactic cytokines together with their cognate classical and atypical receptors comprise a complex molecular network involved in nearly all aspects of human health and disease. The Gordon Research Conference (GRC) on Chemotactic Cytokines 2012 is a world premier meeting devoted entirely to understanding these important molecules. This will be our 10th Chemokine GRC, which has been held every other year since 1994, when chemokines first burst onto the scene as the largest cytokine gene family in the human genome. Similar to each preceding conference in this series, Chemokine GRC 2012 will bring together scientists from a broad range of biomedical disciplines to showcase the latest unpublished research findings that cover all aspects of chemokine function and provide a high-quality scientific forum to discuss their potential implications, including translation to the clinic. The program of this meeting will cover basic biochemical and biological aspects of chemokines as related to their contributions to leukocyte migration, emigration, immune tissue organization and function; the role of chemokines during inflammation, including infectious diseases and autoimmunity in distinct organs and tissues; and multifaceted contributions of chemokines to cancer pathogenesis. In addition, for the first time in the history of this conference, we will introduce he Gordon Research Seminars (GRS), a satellite meeting for bench scientists at the graduate and postdoctoral level. GRS will provide a forum where young researchers can present their work and receive feedback on their ongoing research projects from their peers and a selected panel of senior experts. GRS will promote grassroots level integration and networking within the field of chemokine research. We fully anticipate that the scientific discussions, research talks, poster sessions, and informal interactions between the participants of this conference will contribute to advancing our understanding of molecular mechanisms of chemokine involvement in disease pathogenesis. This will set the basis for the development of new collaborative projects leading to new discoveries and ultimately resulting in new therapies and approaches to treat debilitating human disease, including inflammatory and autoimmune diseases and cancer. PUBLIC HEALTH RELEVANCE: The Gordon Research Conference on Chemotactic Cytokines and the Gordon Research Seminar will bring together chemokine scientists from a variety of biomedical disciplines at all levels of this endeavor, including established investigators, junior investigators, and future generations of chemokine researchers. Scientific presentations, discussions and poster sessions during this conference will expand our understanding of the mechanisms by which chemokines contribute to health and disease. It is anticipated that the collegial and cooperative atmosphere that has traditionally characterized these conferences will provide the perfect setting for the intellectual development, cross-fertilization and future collaborations that are so vital to keep this field at the forefront of scientific innovation and discovery.

描述（由申请人提供）：趋化因子，结构同源，功能不同的趋化细胞因子以及它们的同源经典和非典型受体包括一个复杂的分子网络，几乎涉及人类健康和疾病的各个方面。戈登研究会议（GRC）关于趋化性细胞因子2012 2012是一次全球首屈一指的会议，完全致力于理解这些重要分子。这将是我们的第十个趋化因子GRC，该GRC自1994年以来每隔一年就举行一次，当时趋化因子首次成为人类基因组中最大的细胞因子基因家族。与本系列的每个上次会议类似，Chemokine GRC 2012将从各种生物医学学科中汇集科学家，以展示最新的未发表的研究发现，涵盖了趋化因子功能的各个方面，并提供了一个高质量的科学论坛，以讨论其潜在含义，包括转化为临床。这次会议的计划将涵盖趋化因子的基本生化和生物学方面，与它们对白细胞迁移，移民，免疫组织组织和功能的贡献有关；趋化因子在炎症中的作用，包括在不同的器官和组织中的传染病和自身免疫性；趋化因子对癌症发病机理的多方面贡献。此外，这是本次会议历史上的第一次，我们将介绍He Gordon Research研讨会（GRS），这是毕业生和博士后级别的替补席科学家卫星会议。 GRS将提供一个论坛，年轻的研究人员可以在其中介绍他们的工作，并从同龄人和精选的高级专家小组中就正在进行的研究项目获得反馈。 GRS将促进趋化因子研究领域内的基层整合和网络。我们完全预料到，这次会议的参与者之间的科学讨论，研究谈判，海报会议以及非正式的互动将有助于促进我们对趋化因子参与疾病发病机理的分子机制的理解。这将为开发新的合作项目的发展奠定基础，并最终导致新的疗法和方法来治疗衰弱的人类疾病，包括炎症性和自身免疫性疾病和癌症。 公共卫生相关性：戈登趋化细胞因子和戈登研究研讨会的戈登研究会议将在这项努力的各个层次上将趋化因子科学家聚集在一起，包括既定的研究人员，初级研究人员和后代的趋化因子研究人员。在本次会议期间，科学演示，讨论和海报会议将扩展我们对趋化因子对健康和疾病有助的机制的理解。可以预见的是，传统上认为这些会议的合​​作和合作氛围将为智力发展，交叉利用和未来的合作提供理想的环境，这对于使该领域保持科学创新和发现的最前沿至关重要。