2014 Chemotactic Cytokines Gordon Research Conference and Gordon Research Seminar

2014年趋化细胞因子戈登研究大会暨戈登研究研讨会

• 批准号: 8708388
• 负责人: ANDREW D LUSTER
• 金额: $ 1.1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-03-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8708388
• 关键词: Affect; Age; Area; Asians; Autoimmune Diseases; Autoimmunity; Biochemical; Biological; Brain; Cell Communication; Cells; Chemotactic Factors; Clinic; Clinical Research; Collaborations; Communicable Diseases; Complex; Country; Cytokine Gene; Development; Discipline; Disease; Embryonic Development; Emigrations; Ensure; Environment; European; Family; Feedback; Fees; Fertilization; Fostering; Funding; Future; Future Generations; Gene Family; Generations; Goals; Health; Host Defense; Human; Human Genome; Immune; Immunity; Infection; Inflammation; Inflammatory; Intervention; Journals; Lead; Leukocytes; Link; Malignant Neoplasms; Medical; Mentors; Molecular; Neoplasm Metastasis; Oral; Organ; Participant; Pathogenesis; Pathologic Processes; Pathway interactions; Physiological Processes; Play; Positioning Attribute; Postdoctoral Fellow; Request for Applications; Research; Research Personnel; Research Project Grants; Role; Scientist; Seasons; Senior Scientist; Series; Signal Transduction; Social Interaction; Specialist; Students; Therapeutic; Thinking; Time; Tissues; Translations; Travel; United States National Institutes of Health; Work; abstracting; age group; base; cell type; chemokine; chemokine receptor; empowered; experience; frontier; graduate student; human disease; innovation; intercellular communication; medical specialties; meetings; migration; novel; novel strategies; peer; planetary Atmosphere; posters; professor; programs; public health relevance; receptor; research study; success; symposium; therapeutic target; tumor growth

PROJECT SUMMARY Chemokines, the structurally homologous, functionally distinct family of chemotactic cytokines together with their cognate classical signaling and atypical non-signaling receptors comprise a complex molecular network involved in nearly all aspects of human health and disease. The 2014 Gordon Research Conference (GRC) on Chemotactic Cytokines: Positioning Cells in Immunity and Disease is a world premier meeting devoted entirely to understanding these important molecules. This will be our 11th Chemokine GRC, which has been held every other year since 1994, when chemokines first burst onto the scene as the largest cytokine gene family in the human genome. Similar to each preceding conference in this series, Chemokine GRC 2014 will bring together scientists from a broad range of biomedical disciplines to showcase the latest unpublished research findings that cover all aspects of chemokine function and provide a high-quality scientific forum to discuss their potential implications, including translation to the clinic. The program of this meeting will cover basic biochemical and biological aspects of chemokines as related to their contributions to leukocyte migration and emigration, immune tissue organization and function, and their role in inflammation, infection, autoimmunity and cancer. In addition, due to the success of the first Gordon Research Seminar (GRS) on Chemotactic Cytokines in 2012, we will be having this satellite meeting for bench scientists at the graduate and postdoctoral level again in 2014 titled Frontiers in Chemokine Research. GRS provides a forum where young researchers (e.g., students and post-doctoral fellows) can present their work and receive feedback on their ongoing research projects from their peers and a selected panel of senior experts. GRS will promote grassroots level integration and networking within the field of chemokine research. NIH funding is requested to provide partial support for registration for participants. We fully anticipate that the scientific discussions, research talks, poster sessions, and informal interactions between the participants of this conference will contribute to advancing our understanding of molecular mechanisms of chemokine involvement in disease pathogenesis. This will lay the ground work for the development of new collaborative projects, which will lead to new discoveries and ultimately new therapies and approaches to treat debilitating human disease, including inflammatory, infectious and autoimmune diseases and cancer.

项目总结 趋化因子，结构上同源的，功能上不同的趋化细胞因子家族，与 它们同源的经典信号和非典型的非信号受体组成了一个复杂的分子网络 几乎涉及人类健康和疾病的方方面面。2014年戈登研究会议(GRC) 趋化细胞因子：在免疫和疾病中定位细胞是一个完全致力于 来理解这些重要的分子。这将是我们的第11届趋化因子GRC，每隔一年 自1994年以来的另一年，当趋化因子作为最大的细胞因子基因家族首次出现在 人类基因组。与本系列之前的每一次会议类似，Chemokine GRC 2014将汇集 来自广泛的生物医学学科的科学家展示最新的未发表的研究成果 它涵盖了趋化因子功能的所有方面，并提供了一个高质量的科学论坛来讨论其潜力 影响，包括翻译到临床。本次会议的议程将包括基础生化和 趋化因子与其对白细胞迁移和迁出的贡献有关的生物学方面， 免疫组织的组织和功能，以及它们在炎症、感染、自身免疫和癌症中的作用。在……里面 此外，由于2012年首届戈登趋化细胞因子研究研讨会(GRS)的成功， 我们将在2014年再次为研究生和博士后级别的板凳科学家举行这次卫星会议 题为《趋化因子研究前沿》。GRS提供了一个论坛，年轻的研究人员(如学生和 博士后研究员)可以介绍他们的工作，并从 他们的同行和一个选定的高级专家小组。GRS将促进基层融合和 在趋化因子研究领域内建立联系。美国国立卫生研究院要求提供资金以提供部分支持 参赛者注册。我们完全期待着科学讨论，研究讲座，海报会议， 和本次会议与会者之间的非正式互动将有助于推动我们的 了解趋化因子参与疾病发病的分子机制。这将为 为开发新的合作项目进行基础工作，这将导致新的发现和 最终，治疗包括炎症、传染性疾病在内的令人衰弱的人类疾病的新疗法和方法 自身免疫性疾病和癌症。