Environmental Toxicology and Epidemiology Pre/Post Doctoral Research Training

描述（由申请人提供） 该计划的目标是通过提供跨学科的研究培训，将环境机制毒理学和环境分子流行病学与人类疾病预防应用相结合，培养环境健康科学（EHS）的未来领导者。该计划基于这样的前提，即专门从事毒理学或流行病学的现代EHS科学家需要多学科方法的培训，以便进行转化研究，包括基因组学，蛋白质组学和生物信息学的不断发展的技术。拟议的计划是研究人员目前计划的演变，该计划提供了25年的机械毒理学培训。这些变化使他们能够利用最近教师的扩张进行尖端的跨学科研究。 博士前学员将专门研究环境流行病学或机械毒理学，并将参加非专业领域的基础课程和高级课程（即，流行病学学员参加毒理学课程，反之亦然）。此外，还有翻译研究和生物信息学课程的共同核心课程。为了适应该计划的扩展，研究人员要求在此提交8个博士前和4个博士后职位（0级，1级和2级），从上一个周期的6个博士前和2个博士后职位增加。该培训补助金的受训人员支持的预期期限为两年，尽管博士前培训的预期总期限为4-5年。鼓励博士后学员在培训的第一年提交F32个人NRSA博士后奖学金申请。合格的申请人必须证明在EHS机械毒理学或机械导向的流行病学研究的职业动机。博士预科学员必须具有学士学位，并有相关的科学课程准备，并将被录取为博士。该计划在EHS部门，这在毒理学研究生培训的杰出历史。博士后研究员必须具有博士，医学博士，DVM或其他适当的博士学位。尽管研究人员预计，大多数博士后培训生将拥有博士学位。除了获得临床学位外，他们还预计为持有临床学位的候选人提供1-2个博士后研究金。 相关性：该计划将为环境健康科学家提供新兴研究方法和技术的跨学科培训，以加快研究成果的克里思，促进人类疾病预防环境暴露。

DESCRIPTION (provided by applicant) The objective of this program is to train future leaders in environmental health sciences (EHS) by providing transdisciplinary research training that bridges environmental mechanistic toxicology and environmental molecular epidemiology with applications to human disease prevention. The program is based on the premise that modern EHS scientists specializing in toxicology or epidemiology require training in multiple disciplinary approaches in order to conduct translational research, including the evolving technologies of genomics, proteomics and bioinformatics. The proposed program is an evolution of the investigators' current program which has provided training in mechanistic toxicology for 25 years. The changes allow them to capitalize on a recent expansion in faculty conducting cutting-edge transdisciplinary research. Pre-doctoral trainees will specialize in environmental epidemiology or mechanistic toxicology, and will take a foundation course and an advanced course in the non-specialization area (i.e., epidemiology trainees take toxicology courses and visa versa). In addition, there is a common core curriculum of translational research and bioinformatics courses. To accommodate the program's expansion, the investigators request 8 pre-doctoral and 4 postdoctoral positions (at levels 0,1 and 2) in this submission, increased from 6 pre-doctoral and 2 postdoctoral positions in the last cycle. The expected duration of trainee support on this training grant is two years, though the expected total duration of pre-doctoral training is 4-5 years. Postdoctoral trainees will be encouraged to submit an F32 Individual NRSA Postdoctoral Fellowship application in their first year of training. Qualified applicants must demonstrate motivation for careers in EHS mechanistic toxicology or mechanistically-oriented epidemiology research. Pre-doctoral trainees must have a baccalaureate degree with relevant scientific coursework preparation and will be enrolled in a Ph.D. program in the Department of EHS, which has a distinguished history of graduate training in toxicology. Postdoctoral fellows must have the PhD, MD, DVM, or other appropriate doctoral degree. Although the investigators expect that most postdoctoral trainees will hold Ph.D. degrees, they also anticipate offering 1-2 postdoctoral fellowships to candidates holding clinical degrees. Relevance: This program will provide transdisciplinary training of environmental health scientists in emerging research approaches and technologies to increase the tempo of research findings that promote human disease prevention from environmental exposures.