Parent Mediation of Child Anxiety CBT Outcome

家长对儿童焦虑 CBT 结果的调解

• 批准号: 8306942
• 负责人: JEREMY W PETTIT
• 金额: $ 57.82万
• 依托单位: FLORIDA INTERNATIONAL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8306942
• 关键词: Adolescent; Age; Anxiety; Anxiety Disorders; Behavior; Child; Clinic; Clinical Trials; Clinical Trials Design; Cognitive Therapy; Complex; Controlled Clinical Trials; DSM-IV; Data; Data Analyses; Enrollment; Equation; Family; Generalized Anxiety Disorder; Grant; Growth; Individual; Interview; Lead; Literature; Measures; Mediating; Mediation; Mediator of activation protein; Modeling; Mothers; Negative Reinforcements; Outcome; Outcome Measure; Outcomes Research; Parenting behavior; Parents; Participant; Positive Reinforcements; Procedures; Psychological reinforcement; Questionnaires; Randomized; Randomized Clinical Trials; Relative (related person); Research; Research Design; Resources; Schedule; Separation Anxiety Disorder; Social Phobia; Specificity; Telephone Interviews; Testing; Therapeutic; Training; Treatment outcome; Wood material; alternative treatment; base; childhood anxiety; design; follow-up; human subject; informant; interest; parent grant; parental influence; programs; prototype; research study; response; skills; skills training; therapy outcome; treatment program; treatment response

DESCRIPTION (provided by applicant): This application proposes a mediation-outcome research study evaluating the specificity, mediation, and treatment outcome enhancement of parent involvement for reducing anxiety disorders in children. The study targets the same DSM-IV anxiety disorders targeted in previous clinical trials and that are most common in children: social phobia, generalized anxiety disorder, and separation anxiety disorder. Using a controlled clinical trial design, 336 children (ages 8-11 years) and their parents will be admitted to treatment over the five years of the study, yielding an estimated 236 treatment completers at one year follow-up. Participants will be randomly assigned to one of the three treatment conditions. Two parent involvement conditions (1) ICBT+Parent Reinforcement Skills Training (ICBT+RFST) (i.e., increasing parental use of positive reinforcement and decreasing negative reinforcement) and (2) ICBT + Parent Relationship Skills Training (ICBT- RLST) (i.e., increasing parental autonomy granting and increasing parental child acceptance), and (3) a "basic" ICBT without additional parent involvement components as a baseline comparison condition. Children and parents will be assessed at pretreatment, midtreatment, posttreatment, and one-year follow up with questionnaire measures, the child and parent versions of the interview schedules, and observational measures. Three sets of hypotheses will be tested. The first set tests for "specificity of effects," i.e., whether the addition of specific treatment components has the expected specific effects on the appropriately targeted parenting skills; the second set for "mediation," i.e., whether the effects of changes in the hypothesized mediators are related to significant positive change in child treatment outcome. The third set tests for differential treatment outcome (i.e., whether positive change in child treatment outcome in the parent involvement conditions is significantly greater than positive change in child treatment outcome in the ICBT treatment condition, a baseline comparison condition).The multi-analytic strategies that will be used in the analysis of the data (including structural equation modeling and other complex data analytic strategies e.g., growth curve modeling) are described in detail under the Data Analysis Plan. This application proposes a mediation-outcome child anxiety treatment study that evaluates the specificity, mediation, and treatment outcome enhancement of two distinct strategies for involving parents in their child's treatment relative to individual treatment.

描述（由申请人提供）：本申请提出了一项中介-结果研究，评估父母参与减少儿童焦虑障碍的特异性、中介和治疗结果增强。该研究的目标与之前的临床试验中针对的DSM-IV焦虑症相同，这些焦虑症在儿童中最常见：社交恐惧症、广泛性焦虑症和分离焦虑症。采用对照临床试验设计，336名儿童（8-11岁）及其父母将在五年的研究中接受治疗，在一年的随访中估计有236名治疗完成。参与者将被随机分配到三种治疗条件之一。两个父母参与条件(1)ICBT+父母强化技能培训（ICBT+RFST）（即增加父母对积极强化的使用，减少消极强化）和(2)ICBT+父母关系技能培训（ICBT- RLST）（即增加父母的自主权和增加父母对孩子的接受），以及(3)一个“基本”ICBT，没有额外的父母参与成分作为基线比较条件。儿童和家长将在治疗前、治疗中、治疗后以及一年的随访中进行评估，包括问卷测量、儿童和家长版本的访谈时间表以及观察测量。将测试三组假设。第一组测试“效果的特异性”，即，特定治疗成分的添加是否对适当的有针对性的养育技能具有预期的特定效果；第二组是“中介”，即假设中介的变化是否与儿童治疗结果的显著积极变化有关。第三组检验差异治疗结果（即，父母参与条件下儿童治疗结果的积极变化是否显著大于ICBT治疗条件下儿童治疗结果的积极变化，这是一种基线比较条件）。数据分析计划中详细描述了将用于数据分析的多分析策略（包括结构方程建模和其他复杂数据分析策略，例如增长曲线建模）。本申请提出了一项中介-结果儿童焦虑治疗研究，该研究评估了两种不同策略的特异性、中介和治疗结果的增强，这些策略使父母参与到孩子的治疗中，而不是单独治疗。

项目成果

HPA AXIS RELATED GENES AND RESPONSE TO PSYCHOLOGICAL THERAPIES: GENETICS AND EPIGENETICS.

• DOI: 10.1002/da.22430
• 发表时间: 2015-12
• 期刊: Depression and anxiety
• 影响因子: 7.4
• 作者: Roberts S;Keers R;Lester KJ;Coleman JR;Breen G;Arendt K;Blatter-Meunier J;Cooper P;Creswell C;Fjermestad K;Havik OE;Herren C;Hogendoorn SM;Hudson JL;Krause K;Lyneham HJ;Morris T;Nauta M;Rapee RM;Rey Y;Schneider S;Schneider SC;Silverman WK;Thastum M;Thirlwall K;Waite P;Eley TC;Wong CC
• 通讯作者: Wong CC

Does Training Parents in Reinforcement Skills or Relationship Skills Enhance Individual Youths' Cognitive Behavioral Therapy for Anxiety? Outcome, Specificity, and Mediation.

• DOI: 10.1177/21677026211016402
• 发表时间: 2022-03
• 期刊: CLINICAL PSYCHOLOGICAL SCIENCE
• 影响因子: 4.8
• 作者: Silverman, Wendy K.;Rey, Yasmin;Marin, Carla E.;Jaccard, James;Pettit, Jeremy W.
• 通讯作者: Pettit, Jeremy W.

Attentional Control Scale for Children: Factor Structure and Concurrent Validity Among Children and Adolescents Referred for Anxiety Disorders.

儿童注意力控制量表：因焦虑症而转介的儿童和青少年的因素结构和同时有效性。

• DOI: 10.1002/jclp.22346
• 发表时间: 2017
• 期刊: Journal of clinical psychology
• 影响因子: 3
• 作者: Melendez,Raquel;Bechor,Michele;Rey,Yasmin;Pettit,JeremyW;Silverman,WendyK
• 通讯作者: Silverman,WendyK

Parent involvement enhances CBTs for anxiety disorders in Hispanic/Latino youth: Acculturation as a moderator.

• DOI: 10.1037/ccp0000770
• 发表时间: 2022-10
• 期刊: JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY
• 影响因子: 5.9
• 作者: Patriarca, Guadalupe C;Rey, Yasmin;Marin, Carla E;Yeguez, Carlos E;Pettit, Jeremy W;Silverman, Wendy K
• 通讯作者: Silverman, Wendy K

The role of attentional shifting in the relation between error monitoring and anxiety in youth.

• DOI: 10.1016/j.pscychresns.2022.111507
• 发表时间: 2022-08
• 期刊: PSYCHIATRY RESEARCH-NEUROIMAGING
• 影响因子: 2.3
• 作者: Ramos, Michelle L.;Bechor, Michele;Casas, Alejandro;Pettit, Jeremy W.;Silverman, Wendy K.;Reeb-Sutherland, Bethany C.
• 通讯作者: Reeb-Sutherland, Bethany C.