Renovation of the cage wash facility at the MCG animal facility in Gracewood, GA

乔治亚州 Gracewood 的 MCG 动物设施的笼子清洗设施翻新

• 批准号: 8184269
• 负责人: ALVIN V TERRY
• 金额: $ 26.08万
• 依托单位: AUGUSTA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-15 至 2013-05-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8184269
• 关键词: Address; Aging; Animal Model; Appointment; Area; Basic Science; Behavioral; Bioinformatics; Biomedical Research; Biometry; Cancer Center; Canis familiaris; Cardiovascular Diseases; Child health care; Clinical; Clinical Research; Diabetes Mellitus; Employee; Ensure; Epidemiology; Equipment; Excision; Extramural Activities; Faculty; Family suidae; Floor; Funding; Grant; Growth; Health Sciences; Infection; Inflammation; Institutes; Institution; Laboratory Animals; Malignant Neoplasms; Molecular Genetics; NCI Center for Cancer Research; National Cancer Institute; Obesity; Patients; Physiological; Positioning Attribute; Public Health; Research; Research Infrastructure; Research Personnel; Rodent; Safety; School Dentistry; Surface; System; Translational Research; United States National Institutes of Health; Vision; Work; aged; animal care; animal facility; base; brain behavior; building renovation; human disease; medical schools; nonhuman primate; operation; programs; research facility; sound; translational study; wasting

DESCRIPTION (provided by applicant): MCG concentrates its research efforts into seven areas of focus: brain and behavior, cancer, cardiovascular disease, child health, diabetes/obesity, infection/inflammation and vision. The institutions research-related initiatives include: 7 Optimizing Discovery Institutes to interlink basic and translational research 7 Working to become a National Cancer Institute designated cancer center 7 Enhancing competitiveness for extramural research funding, particularly in basic, clinical, and translational studies 7 Enhancing research initiatives related to public health, particularly in biostatistics and epidemiology 7 Enhancing clinical research infrastructure in areas such as bioinformatics, biostatistics, and epidemiology to expand patient-based research A number of these programs utilize animal models of human diseases in which a wide range of molecular, genetic, behavioral and physiological approaches are employed. MCG has shown a 263.575% growth in biomedical research funding over the past 10 years. More than 60% of MCG's sponsored research funding comes from highly competitive National Institutes of Health grants which increased 119% in the School of Medicine in the past decade. The appointment and ongoing recruitment of new faculty, a rapidly expanding NIH funding base, multiple equipment purchases construction of the $40M (165,000 ft.2) Cancer Research Center, $34M (200,000 ft.2) Health Science Building, $110 M (274,900 ft. 2) School of Dentistry building and renovation of multiple basic science laboratories and animal facilities ($20M, 200,000 ft.2) position MCG to continue achieving further levels of excellence in biomedical research. The operation of a well-equipped, research facility is essential for MCG's continued recruitment of new research faculty, conduct of currently funded research and continued growth of its biomedical research programs. This significant growth of biomedical research at MCG is tempered by the aging equipment of the Animal Care Facility (ACF) located 12 miles away in Gracewood, GA. Aging of the facility's rack washer and bottle washer contribute to the lack of efficiency of the husbandry tasks that must be performed to ensure regulatory compliance and safety when handling waste and manipulanda used by various species (nonhuman primates, swine, canines and rodents). The decrease in efficiency can negatively impact the current group of researchers, ongoing recruitments and planned program expansion initiatives. Thus, this application is for support to renovate the animal facility cage wash facility at the Gracewood Animal Care Facility. The specific aims of this proposal are: 1. Removal of the aged cage rack washer and bottle washer 2. Installation of a pit to mount the new rack washer in in order for it to be level on grade 3. Installation of a new larger capacity and greener rack washer and bottle washer. 4. Install epoxy floor system in the associated cage wash areas, (360 ft2 ) These aims will address the increasing demands of the facility operations, provide a durable flooring surface for sanitization, implement ergonomically sound construction features for employee safety and facilitate the growing Green Sustainability Initiative of the Medical College of Georgia.

描述(申请人提供)：MCG专注于七个重点领域的研究：大脑与行为、癌症、心血管疾病、儿童健康、糖尿病/肥胖、感染/炎症和视力。这些机构与研究相关的举措包括：7优化发现研究所，将基础研究和转译研究联系起来7努力成为国家癌症研究所指定的癌症中心7增强外部研究资金的竞争力，特别是在基础、临床和转译研究方面7加强与公共卫生有关的研究倡议，特别是在生物统计学和流行病学方面7加强生物信息学、生物统计学和流行病学等领域的临床研究基础设施，以扩大以患者为基础的研究其中一些项目利用人类疾病的动物模型，其中广泛使用了分子、遗传、行为和生理方法。在过去的10年里，MCG的生物医学研究经费增长了263.575%。MCG赞助的研究经费的60%以上来自竞争激烈的国立卫生研究院的拨款，在过去十年中，医学院的拨款增加了119%。新教师的任命和正在进行的招聘，NIH迅速扩大的资金基础，多种设备的购买建设耗资4000万美元(16.5万英尺2)的癌症研究中心，3400万美元(20万英尺2)的健康科学大楼，1.1亿美元(274,900英尺)。2)牙科学校的建设和多个基础科学实验室和动物设施的翻新(2000万美元，20万平方英尺2)使MCG继续在生物医学研究方面取得更高水平的卓越成就。设备齐全的研究机构的运营对于MCG继续招聘新的研究人员、进行目前资助的研究以及其生物医学研究项目的持续增长至关重要。MCG生物医学研究的显著增长受到位于12英里外的佐治亚州格雷斯伍德的动物护理设施(ACF)老化设备的影响。该设施的洗架机和洗瓶机老化，导致在处理各种物种(非人灵长类动物、猪、犬类和啮齿动物)使用的废物和操纵品时，必须执行的畜牧业任务缺乏效率，以确保遵守法规和确保安全。效率的下降可能会对当前的研究人员群体、正在进行的招聘和计划中的项目扩展倡议产生负面影响。因此，这项申请是为了支持翻新格雷斯伍德动物护理设施的动物设施笼子清洗设施。这项建议的具体目标是：1.拆除陈旧的笼式垫圈和洗瓶机2.安装一个坑来安装新的垫圈，使其处于3级水平。安装新的容量更大、更环保的垫圈和洗瓶机。4.在相关的笼子洗涤区安装环氧地板系统(360平方英尺)这些目标将满足设施运营日益增长的需求，提供耐用的地板表面进行消毒，实施符合人体工程学的合理结构特征，以确保员工安全，并促进佐治亚医学院日益增长的绿色可持续发展倡议。