Renovation of the cage wash facility at the MCG animal facility in Gracewood, GA

乔治亚州 Gracewood 的 MCG 动物设施的笼子清洗设施翻新

• 批准号: 8184269
• 负责人: ALVIN V TERRY
• 金额: $ 26.08万
• 依托单位: AUGUSTA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-15 至 2013-05-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8184269
• 关键词: Address; Aging; Animal Model; Appointment; Area; Basic Science; Behavioral; Bioinformatics; Biomedical Research; Biometry; Cancer Center; Canis familiaris; Cardiovascular Diseases; Child health care; Clinical; Clinical Research; Diabetes Mellitus; Employee; Ensure; Epidemiology; Equipment; Excision; Extramural Activities; Faculty; Family suidae; Floor; Funding; Grant; Growth; Health Sciences; Infection; Inflammation; Institutes; Institution; Laboratory Animals; Malignant Neoplasms; Molecular Genetics; NCI Center for Cancer Research; National Cancer Institute; Obesity; Patients; Physiological; Positioning Attribute; Public Health; Research; Research Infrastructure; Research Personnel; Rodent; Safety; School Dentistry; Surface; System; Translational Research; United States National Institutes of Health; Vision; Work; aged; animal care; animal facility; base; brain behavior; building renovation; human disease; medical schools; nonhuman primate; operation; programs; research facility; sound; translational study; wasting

DESCRIPTION (provided by applicant): MCG concentrates its research efforts into seven areas of focus: brain and behavior, cancer, cardiovascular disease, child health, diabetes/obesity, infection/inflammation and vision. The institutions research-related initiatives include: 7 Optimizing Discovery Institutes to interlink basic and translational research 7 Working to become a National Cancer Institute designated cancer center 7 Enhancing competitiveness for extramural research funding, particularly in basic, clinical, and translational studies 7 Enhancing research initiatives related to public health, particularly in biostatistics and epidemiology 7 Enhancing clinical research infrastructure in areas such as bioinformatics, biostatistics, and epidemiology to expand patient-based research A number of these programs utilize animal models of human diseases in which a wide range of molecular, genetic, behavioral and physiological approaches are employed. MCG has shown a 263.575% growth in biomedical research funding over the past 10 years. More than 60% of MCG's sponsored research funding comes from highly competitive National Institutes of Health grants which increased 119% in the School of Medicine in the past decade. The appointment and ongoing recruitment of new faculty, a rapidly expanding NIH funding base, multiple equipment purchases construction of the $40M (165,000 ft.2) Cancer Research Center, $34M (200,000 ft.2) Health Science Building, $110 M (274,900 ft. 2) School of Dentistry building and renovation of multiple basic science laboratories and animal facilities ($20M, 200,000 ft.2) position MCG to continue achieving further levels of excellence in biomedical research. The operation of a well-equipped, research facility is essential for MCG's continued recruitment of new research faculty, conduct of currently funded research and continued growth of its biomedical research programs. This significant growth of biomedical research at MCG is tempered by the aging equipment of the Animal Care Facility (ACF) located 12 miles away in Gracewood, GA. Aging of the facility's rack washer and bottle washer contribute to the lack of efficiency of the husbandry tasks that must be performed to ensure regulatory compliance and safety when handling waste and manipulanda used by various species (nonhuman primates, swine, canines and rodents). The decrease in efficiency can negatively impact the current group of researchers, ongoing recruitments and planned program expansion initiatives. Thus, this application is for support to renovate the animal facility cage wash facility at the Gracewood Animal Care Facility. The specific aims of this proposal are: 1. Removal of the aged cage rack washer and bottle washer 2. Installation of a pit to mount the new rack washer in in order for it to be level on grade 3. Installation of a new larger capacity and greener rack washer and bottle washer. 4. Install epoxy floor system in the associated cage wash areas, (360 ft2 ) These aims will address the increasing demands of the facility operations, provide a durable flooring surface for sanitization, implement ergonomically sound construction features for employee safety and facilitate the growing Green Sustainability Initiative of the Medical College of Georgia.

描述（由申请人提供）：MCG将其研究工作集中在七个重点领域：大脑和行为，癌症，心血管疾病，儿童健康，糖尿病/肥胖，感染/炎症和视力。机构与研究相关的举措包括：7个优化发现机构，以互换基本和翻译研究7致力于成为国家癌症研究所指定的癌症中心7增强竞争范围内研究资金的竞争力，尤其是基础，临床，翻译研究7增强了与公共健康相关的研究，尤其是在生物阶段和临床研究方面相关的研究。生物统计学和流行病学扩展基于患者的研究许多这些程序利用人类疾病的动物模型，其中采用了广泛的分子，遗传，行为和生理方法。在过去的10年中，MCG的生物医学研究资金增长了263.575％。 MCG赞助的研究资金中有60％以上来自竞争激烈的国家卫生研究院，在过去的十年中，医学院增长了119％。任命和持续招募新教师，一个迅速扩大的NIH资金基础，多次设备购买4000万美元（165,000英尺2）癌症研究中心，3400万美元（200,000英尺2）卫生科学大楼，110 m（274,900ft。2274,900ft。2），继续建造牙科和翻新工具，麦克（Mc），麦克（Mc）200米（200米）在生物医学研究方面取得了进一步的卓越水平。设备齐全的研究机构的运作对于MCG继续招募新的研究教师，目前资助的研究以及其生物医学研究计划的持续增长至关重要。 MCG生物医学研究的显着增长被位于佐治亚州格雷伍德市12英里外的动物护理设施（ACF）的衰老设备所抑制。该设施的机架洗衣机和瓶洗衣机的老化有助于缺乏饲养任务的效率，以确保在处理各种物种（非人类灵长类动物，猪，猪，犬和啮齿动物）使用的废物和曼尼普兰达时，必须执行监管合规性和安全性。效率的下降可能会对当前的研究人员，持续招聘和计划扩展计划产生负面影响。因此，此应用是为了支持格蕾丝伍德动物护理设施的动物设施清洗设施。该提案的具体目的是：1。拆除老化的笼架垫圈和瓶洗衣机2。安装坑以安装新的机架垫圈，以便在3级上保持水平。安装新的更大容量和更绿色的机架垫圈和瓶洗衣机。 4.在相关的笼式洗涤区安装环氧地板系统，（360 ft2）这些目标将解决设施操作的不断增长的需求，为耐用的地板提供消毒，实施符合人体工程学的构造特征，并促进乔治亚医学院医学院的绿色可持续性启动。