Short Course on Statistical Genetics & Genomics

统计遗传学短期课程

• 批准号: 8478137
• 负责人: Hemant K. Tiwari
• 金额: $ 20.84万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2015-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8478137
• 关键词: Alabama; Books; Characteristics; Clinical; Communities; Complex; Complex Genetic Trait; Computer software; Computers; Data; Data Analyses; Development; Disease; Education; Educational process of instructing; Evaluation; Faculty; Fees; Funding; Genetic; Genomics; Glean; Human; Language; Lead; Learning; Location; Mental disorders; Methods; Modification; National Institute of General Medical Sciences; Participant; Postdoctoral Fellow; Request for Proposals; Research; Research Personnel; Resources; Rotation; Scientist; Selection Criteria; Series; Services; Staging; Statistical Methods; Students; Susceptibility Gene; System; Training; Travel; Universities; Visit; Work; career; disability; education evaluation; experience; genetic analysis; graduate student; lectures; meetings; member; programs; public health relevance; responsible research conduct; trait; web site

DESCRIPTION (provided by applicant): Major efforts are under way to uncover the specific genetic components of many complex human disorders and quantitative traits. These efforts are generating an unprecedented wealth of data that requires sophisticated statistical analysis in order to maximize the information gleaned from each study. Likewise, many advances have been made in statistical methods for the study of complex genetic traits, and new statistical methods continue to be promulgated. To expedite and significantly advance the search for specific genes that predispose to these complex traits, we propose a series of annual hands-on short courses on statistical genetics and statistical genomics which will enable a far greater number of researchers, including clinical researchers, to participate in, contribute to, and lead such research. These short courses will help equip students, post-doctoral fellows, junior investigators and senior investigators new to the field with the statistical genetic approaches necessary to expedite genomic discovery. The courses will be taught by leading experts in statistical genetics/genomics. Each 5-day course will provide substantial "hands-on" computer training that will effectively increase the number and the expertise of investigators who are pursuing genetic and genomic research. We expect approximately 50 students to attend each course, allowing for intensive interaction between students and faculty. Lectures will be supplemented with extensive discussion sessions, handouts, presentation of worked examples, and interactive demonstrations of statistical genetic data analyses. Finally, we will also initiate a new bursary service, providing funding for 10 course participants to travel to visit a course faculty member of their choice to help initiate or finish a particular project. This will provide an unprecedented collaborative opportunity for course participants and faculty.

描述（由申请人提供）：目前正在努力揭示许多复杂的人类疾病和数量性状的特定遗传成分。这些努力正在产生前所未有的大量数据，需要复杂的统计分析才能最大限度地利用每项研究收集的信息。同样，用于研究复杂遗传性状的统计方法也取得了许多进展，并且新的统计方法不断颁布。为了加快并显着推进对导致这些复杂性状的特定基因的搜索，我们提出了一系列关于统计遗传学和统计基因组学的年度实践短期课程，这将使更多的研究人员，包括临床研究人员，能够参与、贡献和领导此类研究。这些短期课程将帮助刚进入该领域的学生、博士后研究员、初级研究人员和高级研究人员掌握加快基因组发现所需的统计遗传学方法。这些课程将由统计遗传学/基因组学领域的顶尖专家教授。每个为期 5 天的课程将提供大量的“实践”计算机培训，这将有效增加从事遗传和基因组研究的研究人员的数量和专业知识。我们预计每门课程大约有 50 名学生参加，以便学生和教师之间进行密切互动。讲座将辅以广泛的讨论会、讲义、工作示例的演示以及统计遗传数据分析的交互式演示。最后，我们还将启动一项新的助学金服务，为 10 名课程参与者提供资金，让他们前往拜访他们选择的课程教员，以帮助启动或完成特定项目。这将为课程参与者和教师提供前所未有的合作机会。