Short Course on Statistical Genetics & Genomics

描述（由申请人提供）：主要工作正在进行中，以揭示许多复杂的人类疾病和数量性状的特定遗传成分。这些努力正在产生前所未有的数据财富，需要复杂的统计分析，以便最大限度地从每项研究中收集信息。同样，研究复杂遗传性状的统计方法也取得了许多进展，新的统计方法也在不断涌现。为了加快和显著推进对易导致这些复杂性状的特定基因的研究，我们提出了一系列关于统计遗传学和统计基因组学的年度实践短期课程，这将使更多的研究人员，包括临床研究人员，参与、贡献和领导这类研究。这些短期课程将帮助学生、博士后研究员、初级研究人员和新进入该领域的高级研究人员掌握加速基因组发现所需的统计遗传学方法。这些课程将由统计遗传学/基因组学方面的顶尖专家教授。每个为期5天的课程将提供大量的“动手”计算机培训，这将有效地增加从事遗传和基因组研究的调查人员的数量和专业知识。我们预计大约50名学生参加每门课程，允许学生和教师之间的密集互动。讲座将辅以广泛的讨论会议，讲义，工作实例的介绍，以及统计遗传数据分析的互动演示。最后，我们还将启动一项新的助学金服务，为10名课程参与者提供资金，让他们前往访问他们选择的课程教员，帮助他们启动或完成一个特定的项目。这将为课程参与者和教师提供前所未有的合作机会。

DESCRIPTION (provided by applicant): Major efforts are under way to uncover the specific genetic components of many complex human disorders and quantitative traits. These efforts are generating an unprecedented wealth of data that requires sophisticated statistical analysis in order to maximize the information gleaned from each study. Likewise, many advances have been made in statistical methods for the study of complex genetic traits, and new statistical methods continue to be promulgated. To expedite and significantly advance the search for specific genes that predispose to these complex traits, we propose a series of annual hands-on short courses on statistical genetics and statistical genomics which will enable a far greater number of researchers, including clinical researchers, to participate in, contribute to, and lead such research. These short courses will help equip students, post-doctoral fellows, junior investigators and senior investigators new to the field with the statistical genetic approaches necessary to expedite genomic discovery. The courses will be taught by leading experts in statistical genetics/genomics. Each 5-day course will provide substantial "hands-on" computer training that will effectively increase the number and the expertise of investigators who are pursuing genetic and genomic research. We expect approximately 50 students to attend each course, allowing for intensive interaction between students and faculty. Lectures will be supplemented with extensive discussion sessions, handouts, presentation of worked examples, and interactive demonstrations of statistical genetic data analyses. Finally, we will also initiate a new bursary service, providing funding for 10 course participants to travel to visit a course faculty member of their choice to help initiate or finish a particular project. This will provide an unprecedented collaborative opportunity for course participants and faculty.