Heartland Unit for Neuroscience Trials

神经科学试验中心地带单位

• 批准号: 8532064
• 负责人: Richard J. Barohn
• 金额: $ 28.59万
• 依托单位: UNIVERSITY OF KANSAS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-30 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8532064
• 关键词: Acceleration; Adult; Ambulatory Care Facilities; Award; Bioinformatics; Child; Cities; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Contracts; County; Endowment; Faculty; Foundations; Funding; Goals; Grant; Housing; Institutes; International; Kansas; Leadership; Letters; Medical; Medical center; Multi-Institutional Clinical Trial; Neurologic; Neurology; Neurosciences; Neurosciences Research; Participant; Patients; Pharmacologic Substance; Positioning Attribute; Recording of previous events; Research; Research Infrastructure; Research Institute; Research Personnel; Resources; Sales; Services; Site; Specialist; Taxes; Training; Translational Research; United States National Institutes of Health; Universities; Work; base; biomedical informatics; drug development; drug discovery; innovation; medical schools; meetings; nervous system disorder; outreach; programs; public-private partnership; response; translational neuroscience

DESCRIPTION (provided by applicant): The University of Kansas (KU) has a rich history and portfolio of neurological clinical and translational research, with over 150 active neuroscience-related clinical trials. Clinical and translational research in Kansas City has accelerated in recet years, and KU's Institute for Advancing Medical Innovations has become a national leader in drug development. KU will capitalize on this momentum and form the Heartland Unit for Neuroscience Trials (HUNT) to provide infrastructure, centralized resources, access to patients, and coordination of our region's neuroscience investigators, thereby increasing their responsiveness to NEXT trials and efficiency in conducting those trials. The HUNT will integrate with and draw on existing institutional resources to form two specific cores dedicated to efficiently meet study requirements: a Regulatory Core (RC) and an Outreach Core (OC). The RC will provide full-service regulatory and contractual support, while the OC will expand the pool of potential research participants and work with investigators to exceed recruitment goals. For the last two decades, KU's Research Institute has supported investigators with comprehensive regulatory and contractual support. More recently, KU developed a Research-Participant-Registration Program deployed across outpatient clinics and supported by a new Bioinformatics program. These existing resources position us well to develop the HUNT as an integrated and cohesive unit for supporting the region's specialist neuroscience investigators. Specifically, the HUNT aims to 1) increase the efficiency and quality of neurological-disease-specific clinical trials by providing a coordinated regional team of specialist investigators with an RC for comprehensive regulatory support and an OC for expanding the pool of potential study participants; 2) extend the reach of neurological-disease-specific clinical trials by training new investigators across the region and the state of Kansas; and 3) enhance the NEXT consortium with unique capabilities for translational drug development.

描述（由申请人提供）：堪萨斯大学（KU）拥有丰富的神经临床和转化研究的历史和投资组合，并进行了150多种与神经科学有关的临床试验。堪萨斯城的临床和转化研究在Recet年代加速了，KU推进医疗创新研究所已成为药物开发的国家领导者。 KU将利用这一势头，并组成神经科学试验（HUNT）的心脏地带单位，以提供基础设施，集中资源，与患者的访问权以及我们地区神经科学研究者的协调，从而提高了他们对下一个试验的反应和进行这些试验的效率。狩猎将与现有的机构资源集成并借鉴，以形成两个专门满足研究要求的特定核心：监管核心（RC）和外展核心（OC）。 RC将提供全方位服务的监管和合同支持，而OC将扩大潜在的研究参与者的库，并与研究人员合作以超过招聘目标。在过去的二十年中，KU的研究所为调查人员提供了全面的监管和合同支持。最近，KU制定了一项研究参与者的注册计划，该计划部署在门诊诊所中，并得到了新的生物信息学计划的支持。这些现有资源的位置很好，可以发展为支持该地区专家神经科学研究人员的综合和凝聚力单元。具体而言，狩猎的目的是1）通过为一个协调的专家研究人员提供全面的监管支持和扩大潜在研究参与者的OC来提高神经疾病特异性临床试验的效率和质量； 2）通过培训该地区和堪萨斯州的新研究人员，扩展了神经疾病特异性临床试验的范围； 3）增强下一个财团具有转化药物开发的独特功能。