High Precision Robotic Weighing System in Support of New Exposure Health Studies
支持新暴露健康研究的高精度机器人称重系统
基本信息
- 批准号:8447261
- 负责人:
- 金额:$ 24.98万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2013
- 资助国家:美国
- 起止时间:2013-07-10 至 2015-07-09
- 项目状态:已结题
- 来源:
- 关键词:Airborne Particulate MatterAreaComputer softwareCore FacilityDataDatabasesEnvironmentEnvironmental ExposureEnvironmental HealthExposure toFundingGenerationsGenesGrantHealthIndividualLaboratoriesLinkManualsMeasurementMonitorParticle SizeParticulateParticulate MatterPopulationPumpReportingResearchResearch DesignResearch PersonnelRespirationRoboticsRunningSamplingStainless SteelSupport SystemSystemTechnologyTimeUncertaintyWritingair monitoringbasecostdesignexperienceimprovedinstrumentinstrumentationlight weightminiaturizenext generationquality assuranceranpirnasetime usetool
项目摘要
DESCRIPTION (provided by applicant): This instrumentation grant seeks funds to purchase a high precision robotic weighing system in support of new exposure tools and health studies. Obtaining this system is directly linked to our long term efforts to develop and use technologies that reduce the uncertainties associated with characterizing individual and population exposures to airborne particulate matter (PM), which has been identified as a critically-important area of research needed to improve the establishment of linkages between exposures to sized particles and adverse health effects (NRC, 2004). Specifically, a high precision robotic weighing facility is
needed for weighing filters that are generated from the next generation of personal particulate monitor samplers that have been developed under the Genes, Environment and Health Initiative. These monitors have been designed to be light-weight and have extended run time by using low flow-rate pumps. The robotic weighing system made by Measurements Technology Laboratory (MTL) is an integrated system designed around the concept of being able to provide high precision gravimetric determinations of the particulate matter collected onto filters. The system comprises a tightly-controlled environmental chamber, an inertial mass weighing table, a microbalance and faraday cage, and a robotically controlled automatic sampler that transfers the filters from specially designed stainless steel petri-dishes to the microbalance. The whole system is controlled by software on a PC and the data are written automatically to a database that tracks quality assurance and generates reports. The robotic weighing system would be a major upgrade, replacing a manual weighing system and supporting the needs of an active user group, which we expect to grow with time due to the high precision and high throughput capabilities and lower costs. The system will be part of long running recharge center that is integrated into the Exposure Assessment Facility Core of the P30 Center of Environmental Health in Northern Manhattan that has a vibrant group of investigators carrying out public heath research related to environmental exposures. Institutional support from Columbia will insure that the system is in a state of the art, HEPA filtered laboratory and is well maintained for years to come, allowing time to expand the user group. Based on the experience of multiple groups that currently have the MTL system, we will be able to weigh particulate matter on filters with an uncertainty of d1 ¿g, which opens up many new study designs including the use of the new miniaturized personal monitors that also monitor wearing compliance and estimate respiration rates. This ability to obtain such high precision (and accuracy) of gravimetric determinations of airborne PM concentrations, which is needed for certain applications such as the new generation of low flow air monitors is a primary justification of the need for this instrument. The
ability to do this while increasing sample throughput (decreasing backlogs) and potentially lowering costs significantly will be a major benefit to all facility users.
描述(由申请人提供):该仪器赠款寻求资金购买高精度机器人称重系统,以支持新的暴露工具和健康研究。获得这一系统与我们开发和使用技术的长期努力直接相关,这些技术可以减少与表征个人和人群暴露于空气中颗粒物(PM)相关的不确定性,这已被确定为一个至关重要的研究领域,需要改进大小颗粒物暴露与不良健康影响之间的联系(NRC,2004年)。具体而言,高精度机器人称重设施是
称重过滤器所需要的是从下一代的个人颗粒监测采样器,已根据基因,环境和健康倡议开发。这些监测仪的设计重量轻,并通过使用低流速泵延长了运行时间。由测量技术实验室(MTL)制造的机器人称重系统是一个集成系统,其设计理念是能够对收集到过滤器上的颗粒物进行高精度重量测定。该系统包括一个严格控制的环境室,惯性质量称重台,微量天平和法拉第笼,以及一个机器人控制的自动取样器,将过滤器从专门设计的不锈钢皮氏培养皿转移到微量天平。整个系统由PC上的软件控制,数据自动写入数据库,跟踪质量保证并生成报告。 机器人称重系统将是一次重大升级,取代手动称重系统,并支持活跃用户群的需求,由于高精度和高吞吐量能力以及较低的成本,我们预计该用户群将随着时间的推移而增长。该系统将成为长期运行的再充电中心的一部分,该中心被集成到北方曼哈顿的P30环境健康中心的暴露评估设施核心中,该中心有一个充满活力的调查小组,从事与环境暴露相关的公共健康研究。来自哥伦比亚的机构支持将确保该系统处于最先进的HEPA过滤实验室状态,并在未来几年内得到良好的维护,从而有时间扩大用户群。根据目前使用MTL系统的多个小组的经验,我们将能够以d1?g的不确定性对过滤器上的颗粒物进行称重,这开辟了许多新的研究设计,包括使用新型小型化个人监测器,该监测器还可以监测佩戴依从性并估计呼吸率。 这种获得空气中PM浓度的重量测定的如此高的精度(和准确度)的能力是对该仪器的需求的主要理由,这是诸如新一代低流量空气监测器的某些应用所需要的。的
能够做到这一点,同时增加样品吞吐量(减少积压)和潜在地显著降低成本,将是所有设施用户的主要益处。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Steven N. Chillrud其他文献
Absolute doubly differential angular sputtering yields for 20 keV Kr+ on polycrystalline Cu
多晶铜上 20 keV Kr+ 的绝对双微分角溅射产量
- DOI:
- 发表时间:
2023 - 期刊:
- 影响因子:3.2
- 作者:
Caixia Bu;L. Morrissey;Benjamin C. Bostick;M. Burger;Kyle P Bowen;Steven N. Chillrud;D. Domingue;Catherine A. Dukes;D. Ebel;G. Harlow;P. Hillenbrand;Dmitry A. Ivanov;R. Killen;James M. Ross;Daniel Schury;O. Tucker;Xavier Urbain;Ruitian Zhang;D. W. Savin - 通讯作者:
D. W. Savin
Widespread Pb contamination in urban backyard soils for 100 years identified in soil cores constrained by sup210/supPb and sup137/supCs
通过受 sup210/supPb 和 sup137/supCs 限制的土壤核心确定了城市后院土壤中 100 年来广泛的铅污染
- DOI:
10.1016/j.scitotenv.2023.165407 - 发表时间:
2023-11-15 - 期刊:
- 影响因子:8.000
- 作者:
Franziska C. Landes;Margaret Calcio;Jennifer M. Sobolewski;Kelcey Wallens-Logan;Anna Ledeczi;Yael Kiro;Louise Bolge;James Ross;Steven N. Chillrud;Brian J. Mailloux;Alexander van Geen - 通讯作者:
Alexander van Geen
Steven N. Chillrud的其他文献
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{{ truncateString('Steven N. Chillrud', 18)}}的其他基金
High Resolution Models of Groundwater Metal Exposures
地下水金属暴露的高分辨率模型
- 批准号:
10354269 - 财政年份:2022
- 资助金额:
$ 24.98万 - 项目类别:
High Resolution Models of Groundwater Metal Exposures
地下水金属暴露的高分辨率模型
- 批准号:
10707888 - 财政年份:2022
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$ 24.98万 - 项目类别:
Potential inhaled dose of particulates, biking and cardiovascular indicators
颗粒物的潜在吸入剂量、骑行和心血管指标
- 批准号:
9441097 - 财政年份:2017
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Potential Inhaled Dose of Particulates, Biking and Cardiovascular Indicators
颗粒物、骑行和心血管指标的潜在吸入剂量
- 批准号:
8801250 - 财政年份:2015
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Monitoring Particulate, PAH, Allergen and Microbial Exposures in Asthmatic Kids
监测哮喘儿童的颗粒物、PAH、过敏原和微生物暴露
- 批准号:
9076745 - 财政年份:2015
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Validating Particulate Matter Monitors for Multiple Parameters
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8179830 - 财政年份:2011
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Validating Particulate Matter Monitors for Multiple Parameters
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8331370 - 财政年份:2011
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Smart Miniaturized personal monitors for black carbon and multiple air pollutants
智能微型个人黑碳和多种空气污染物监测仪
- 批准号:
7485240 - 财政年份:2007
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智能微型个人黑碳和多种空气污染物监测仪
- 批准号:
7921792 - 财政年份:2007
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$ 24.98万 - 项目类别:
Smart Miniaturized personal monitors for black carbon and multiple air pollutants
智能微型个人黑碳和多种空气污染物监测仪
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7871510 - 财政年份:2007
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$ 24.98万 - 项目类别:
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