Genes, the Environment, and ME (GEM)

基因、环境和 ME（GEM）

• 批准号: 8478224
• 负责人: Stephanie Malia Fullerton
• 金额: $ 24.59万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8478224
• 关键词: Address; Adopted; Affect; Age; Agriculture; Animal Model; Area; Attitude; Behavior; Bioethics; Biology; Biomedical Research; Clinical; Collaborations; Communication; Communities; Complex; Data; Development; Disease; Educational Curriculum; Educational process of instructing; Ensure; Environment; Environmental Health; Environmental Risk Factor; Epigenetic Process; Ethical Issues; Ethicists; Ethics; Family; Family member; Festival; Fostering; Genes; Genetic; Genome; Goals; Health; Health Policy; Health Sciences; Heart Diseases; Hispanic Americans; Human; Individual; Institution; Instruction; Knowledge; Lead; Learning; Life; Life Style; Link; Malignant Neoplasms; Minority; Modeling; Native Americans; Non-Insulin-Dependent Diabetes Mellitus; Organism; Outcome; Parents; Pathway interactions; Population; Population Heterogeneity; Poverty; Problem Solving; Public Health; Public Health Practice; Research Design; Risk; Rural; School Teachers; Schools; Science; Scientist; Series; Societies; Students; Teacher Professional Development; Thinking; Translating; Translational Research; Underrepresented Minority; United States; Universities; Washington; Work; after-school program; base; career; community based participatory research; design; experience; gene environment interaction; genetic analysis; graduate student; high school; improved; interest; meetings; member; middle school; outreach; programs; public health relevance; research study; science education; skills; teacher; trait; undergraduate student

DESCRIPTION (provided by applicant): The Department of Genome Sciences at the University of Washington (UW) proposes a five year project, Genes, the Environment, and Me (GEM). This project will address the pressing need for deeper understanding of biomedical research among diverse populations and increased representation of underrepresented minorities in biomedical fields through a school and community-focused science education program. The project will be conducted in collaboration with three programs within the UW Office of Minority Affairs and Diversity, the UW Center for Ecogenetics and Environmental Health, and scientists and ethicists at the UW and other biomedical research institutions throughout Washington. GEM will use a Community-Based Participatory Research Approach to involve community members-teachers, students, parents, and community leaders-as equal partners in planning, developing, and implementing project activities. Through these partnerships, we will develop a series of modular lessons focused on a fundamental concept of biology-the interaction of genes and the environment in the determination of traits in all living organisms. The lessons will be used to supplement health and science programs that serve underrepresented K-12 students throughout Washington and other parts of the United States. In addition, Family Science Festivals will involve students, teachers, families, and the community in learning about genetic concepts and health-related conditions in an informal all- age celebration. GEM will work primarily with school districts in the Yakima Valley, a rural agricultural region in central Washington with a high percentage of Hispanic and Native American students, many from high poverty families with limited English proficiency and low educational attainment levels. Complex diseases (i.e. those caused a combination of genetic and environmental factors) such as type 2 diabetes, heart disease, and cancer are important health problems for Hispanic and Native American people, making the teaching of gene- environment interactions an especially compelling topic for this population. GEM will focus primarily on middle and high school students and their teachers to promote deeper understanding of genetic concepts, including how genes and the environment interact to determine traits. Engagement in genetics activities and discussions of ethical issues that affect individuals and society will help students to formulate ideas about their own identity, attitudes, and interests, including career interests. Washington's teaching and learning standards require teachers to incorporate genetic concepts at these grade levels, and therefore they are eager to have well designed lessons to supplement their curriculum. Exposing students, particularly those from traditionally underrepresented communities, to linked career options may encourage some to pursue advanced studies in science and math and ultimately a career in a biomedical field.

描述（由申请人提供）：华盛顿大学（UW）基因组科学系提出了一个为期五年的项目，基因，环境和我（GEM）。该项目将通过一个以学校和社区为重点的科学教育计划，解决对不同人群中生物医学研究的更深入理解的迫切需要，并增加生物医学领域代表性不足的少数民族的代表性。该项目将与华盛顿大学少数民族事务和多样性办公室、华盛顿大学生态遗传学和环境健康中心以及华盛顿大学和华盛顿其他生物医学研究机构的科学家和伦理学家合作开展。GEM将采用以社区为基础的前瞻性研究方法，让社区成员--教师、学生、家长和社区领袖--作为平等的伙伴参与项目活动的规划、开发和实施。通过这些合作伙伴关系，我们将开发一系列模块课程，重点是生物学的基本概念-基因和环境在决定所有生物体特征中的相互作用。这些课程将用于补充健康和科学项目，为华盛顿和美国其他地区代表性不足的K-12学生提供服务。此外，家庭科学节将涉及学生，教师，家庭和社区在学习遗传概念和健康相关的条件在一个非正式的所有年龄的庆祝活动。 GEM将主要与亚基马山谷的学区合作，该山谷是华盛顿中部的一个农村农业地区，西班牙裔和美洲原住民学生比例很高，其中许多人来自英语水平有限和教育水平较低的高度贫困家庭。复杂的疾病（即那些由遗传和环境因素共同引起的疾病），如2型糖尿病、心脏病和癌症，是西班牙裔和美洲原住民的重要健康问题，这使得基因-环境相互作用的教学成为这一人群特别引人注目的话题。GEM将主要侧重于初中和高中学生及其教师，以促进对遗传概念的更深入理解，包括基因和环境如何相互作用以决定性状。参与遗传学活动和影响个人和社会的伦理问题的讨论将帮助学生制定关于自己的身份，态度和兴趣，包括职业兴趣的想法。华盛顿的教学标准要求教师在这些年级纳入遗传学概念，因此他们渴望有精心设计的课程来补充他们的课程。让学生，特别是那些来自传统上代表性不足的社区的学生，接触到相关的职业选择，可能会鼓励一些人追求科学和数学方面的高级研究，并最终在生物医学领域从事职业。