Biostatistics/Medical Informatics

生物统计学和医学信息学核心将由艾伦·哈特森博士和卡梅罗·戈迪奥索博士领导。哈特森博士是罗斯威尔公园癌症研究所生物统计学和生物信息学主席，以及布法罗大学生物统计学主席。他在基础、转换和临床实验设计和分析方面拥有20年的经验。Gaudioso博士是RPCI医学信息学主任、临床数据网络副主任和肿瘤学助理教授。他的研究领域是知识管理和决策支持系统。 生物统计和医疗信息学核心将确保生物统计、生物信息学和医疗信息学的设计和建模支持提供给所有RPCI前列腺癌孢子项目负责人、核心主管和他们的联合调查员。生物统计和医学信息学核心旨在提供统计支持，既考虑到机构的接近，也考虑到个人研究人员的生物统计、生物信息学和医学信息学需求。具体地说，我们的目标是：通过应用适当的生物统计学和生物信息学分析，并就其优势和局限性对其结果进行适当的解释，帮助RPCI卵巢癌孢子的基础、翻译和临床研究人员正确地制定、完善和执行研究目标；建立健全的数据管理系统，有效地管理卵巢癌孢子在支持多学科、多项目、多机构的临床和翻译研究方面的信息学需求，并促进数据共享和信息传播；当数据足够成熟，可以撰写手稿，撰写手稿的统计方法部分，并在形成手稿的其余部分提供专家协作指导时，通知RPCI-UPCI卵巢癌孢子调查人员。预计生物统计和医学信息学核心的服务将被与该孢子有关的所有研究人员广泛使用。生物统计和医疗信息学核心的好处包括提供一支致力于高效和有效合作的始终如一的团队。开发生物统计和医疗信息学核心的好处包括提供一支始终如一的团队，致力于在三个综合癌症中心进行高效合作。

The Biostatistics and Medical Informatics Core will be led by Drs. Alan Hutson and Carmelo Gaudioso. Dr. Hutson is Chair of Biostatistics and Bioinformatics at Roswell Park Cancer Institute (RPCI) and Chair of Biostatistics at the University at Buffalo (UB). He has two decades of experience in basic, translational and clinical experimental design and analysis. Dr. Gaudioso is the Director of Medical Informatics, Associate Director of the Clinical Data Network, and Assistant Professor of Oncology at RPCI. His research area is knowledge management and decision support systems. The Biostatistics and Medical Informatics Core will ensure that biostatistics, bioinformatics and medical informatics design and modeling support is available to all RPCI Prostate Cancer SPORE project leaders and core directors and their co-investigators. The Biostatistics and Medical Informatics Core is designed to provide statistical support that considers both institutional proximity and the biostatistical, bioinformatics and medical informatics needs of individual investigators. Specifically, we aim to: To assist basic, translational and clinical researchers of the RPCI Ovarian Cancer SPORE with proper formulation, refinement and execution of study objectives by applying the appropriate biostatistics and bioinformatics analyses, and providing the appropriate interpretation of their results, in terms of both strengths and limitations; To establish a robust data management system to effectively manage the Ovarian Cancer SPORE's informatics needs in supporting multidisciplinary, multi-project, multi-institutional clinical and translational research and facilitating data sharing and information dissemination; and To notify RPCI-UPCI Ovarian Cancer SPORE investigators when data are sufficiently mature to write a manuscript, to write the statistical methods section of manuscripts and to provide expert collaborative guidance in formulating the rest of the manuscript. It is anticipated that the services of the Biostatistics and Medical Informatics Core will be extensively used by all researchers associated with the SPORE. Benefits to the Biostatistics and Medical Informatics Core include providing a consistent team dedicated to efficient and effective collaboration. Benefits towards developing the Biostatistics and Medical Informatics Core include providing a consistent team dedicated to efficient collaboration across three comprehensive cancer centers.