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中文摘要
翻译
白血病孢子发育研究计划(LSDRP)的总体目标是招募和 支持白血病的发展研究项目,以获得未来的同行评审资金和/或未来的 独立的SPORE项目。支持的研究类型包括基础研究项目, 白血病的临床研究、流行病学研究和癌症预防与控制研究。项目 在LSRDP的支持下,将扩大转化研究的范围,并增加 致力于白血病研究的研究人员LSDRP将与职业发展部合作, 协助发展初级调查员以及征聘和指导少数族裔调查员的方案 investigators.为实现这些目标,提出了以下具体目标 1.支持白血病的发展研究项目,以便将来作为完整的SPORE纳入 项目和其他主要同行评审资金的申请。将征集新的研究项目 并使用发展基金资助。每年向该方案承诺的资金总额为175 000美元 (包括每年来自机构来源的125 000美元配套资金)。这些资金将用于 在整个生命周期内,每年支持3 - 5个发展项目,金额从30 000美元到60 000美元不等。 孢子。 2.促进基础和临床研究人员之间的合作。LSDRP主席将促进 基础和临床研究人员之间的互动,通过共享每周会议,年度孢子 务虚会和小组会议。 3.为初级教员提供指导。所有提交发展研究项目的研究人员 将收到一份书面的科学和统计审查,LSDRP主席将讨论 项目详细。在适当的情况下,导师将确定与初级教师。 相关性(参见说明): 发展研究计划将招募和支持白血病的创新早期研究。
英文摘要
The overall goal of the Leukemia SPORE Developmental Research Program (LSDRP) is to recruit and support developmental research projects in leukemia for future peer-reviewed funding and/or future independent SPORE projects. The types of studies to be supported include projects in basic research, clinical research, epidemiologic studies, and cancer prevention and control research in leukemia. Projects supported under the LSRDP will expand the scope of translational research and increase the number of investigators committed to leukemia research. The LSDRP will work in tandem with the Career Development Program to assist in the development of junior investigators and in the recruitment and mentoring of minority investigators. To accomplish these goals, the following specific aims are proposed 1. To support developmental research projects in leukemia for future incorporation as full SPORE projects and for applications for other major peer-reviewed funding. New research projects will be solicited and funded using developmental funds. A total of $175,000 has been committed annually to this program (including $125,000 per year of matching funds from institutional sources). These funds will be used to support 3-5 developmental projects per year ranging from $30,000 to $60,000 throughout the life of the SPORE. 2. Foster collaborations between basic and clinical researchers. The LSDRP chairs will facilitate interaction between basic and clinical researchers through shared weekly meetings, the annual SPORE retreat, and small group meetings. 3. To provide mentoring to junior faculty. Ail investigators submitting developmental research projects will receive a written scientific and statistical review, and the LSDRP chairs will be available to discuss the projects in detail. Where appropriate, mentors will be identified to work with junior faculty. RELEVANCE (See instructions): The Developmental Research Program will recruit and support innovative early-stage research in leukemia.
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Inhibition of T-cell Receptor Signaling for Treatment of Adult T-cell Leukemia Lymphoma
  • 批准号:
    10684172
  • 项目类别:
  • 资助金额:
    $35.31万
  • 财政年份:
    2022
  • 负责人:
    Lee Ratner
  • 依托单位:
Inhibition of T-cell Receptor Signaling for Treatment of Adult T-cell Leukemia Lymphoma
  • 批准号:
    10518751
  • 项目类别:
  • 资助金额:
    $36.03万
  • 财政年份:
    2022
  • 负责人:
    Lee Ratner
  • 依托单位:
Interaction of HTLV-1 Tax & Hbz in Transformation
  • 批准号:
    10189192
  • 项目类别:
  • 资助金额:
    $18.41万
  • 财政年份:
    2021
  • 负责人:
    Lee Ratner
  • 依托单位:
Role of Protein Kinase C Mutations in Adult T-Cell Leukemia
  • 批准号:
    10322134
  • 项目类别:
  • 资助金额:
    $21.65万
  • 财政年份:
    2021
  • 负责人:
    Lee Ratner
  • 依托单位:
海外基金