Cortical Dynamics of Auditory Attention

听觉注意力的皮层动力学

• 批准号: 8644013
• 负责人: Adrian KC Lee
• 金额: $ 38.63万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-17 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8644013
• 关键词: Accounting; Acoustics; Address; Aging; Area; Attention; Auditory; Behavioral; Behavioral Paradigm; Brain; Central Auditory Processing Disorder; Clinical; Cochlear Implants; Cognitive; Cognitive deficits; Complex; Coupled; Coupling; Crowding; Cues; Data; Devices; Environment; Goals; Hearing; Hearing Aids; Individual; Lead; Life; Link; Magnetic Resonance Imaging; Maintenance; Measures; Performance; Peripheral; Physiological; Population; Process; Psychoacoustics; Reaction Time; Recruitment Activity; Research; Rest; Scanning; Self-Help Devices; Sensory; Signal Transduction; Simulate; Social Interaction; Source; Stimulus; Stream; System; Techniques; Testing; Time; Work; base; computerized data processing; cost; design; directed attention; encephalography; experience; extrastriate visual cortex; hearing impairment; interest; neuroimaging; neurophysiology; next generation; programs; public health relevance; rehabilitation strategy; relating to nervous system; selective attention; simulation; sound

Project Summary / Abstract In order to dynamically follow different conversations in a crowded environment, we must constantly direct attention to the auditory signal of interest and segregate sounds that originated from other sources. Normal- hearing listeners can achieve this task seamlessly, but hearing-impaired listeners, cochlear implant users, and individuals with (central) auditory processing disorders often find communicating in this everyday acoustic environment challenging. The long-term objective of this research is to characterize the cortical dynamics associated with different aspects of auditory attention and to incorporate these brain signals in a next- generation hearing assistive device that helps account for the listener's attentional focus. The current project is built on the hypothesis that there are distributed cortical regions that coordinate top-down and bottom-up auditory attention, and that these regions are functionally coupled to the auditory sensory areas differently depending on the task at hand. The brain dynamics associated with auditory attention are currently not well understood, and thus a necessary first step to achieve our long-term objective is to study the attentional network in normal-hearing listeners. The specific aims of this project seek to identify differences between the cortical regions recruited for attention based on spatial and non-spatial features (Aim 1), as well as how the rest of the cortex compensates when the peripheral auditory signal is degraded by simulating the reduction in spectrotemporal acuity experienced by listeners with hearing impairments and cochlear implant users (Aim 2). Furthermore, we propose to take a systems-level approach and investigate how other cortical regions communicate with the auditory sensory areas in order to coordinate switching and maintenance of attention in a crowded acoustical scene (Aim 3). Our proposal emphasizes designing behavioral paradigms that bridge the gap between psychoacoustics and neuroimaging research, thereby addressing how different regions of the cortex act in concert to aid us in communicating in everyday settings.

项目摘要 /摘要 为了在拥挤的环境中动态遵循不同的对话，我们必须不断地指导 注意感兴趣的听觉信号和源自其他来源的声音。普通的- 听众可以无缝地完成此任务，但是听力受损的听众，人工耳蜗用户和 患有（中央）听觉处理障碍的人通常会发现在这种日常声学中进行交流 环境具有挑战性。这项研究的长期目标是表征皮质动力学 与听觉注意的不同方面相关，并将这些大脑信号纳入接下来的 一代听力辅助设备有助于考虑听众的注意力重点。当前的项目是 建立在以下假设的基础上，即有分布式的皮质区域可以使自上而下和自下而上 听觉的关注，这些区域在功能上与听觉感觉区域耦合在一起 取决于手头的任务。目前与听觉关注相关的大脑动力学不太好 理解，因此实现我们的长期目标的必要第一步是研究注意力 正常听众的网络。该项目的具体目的旨在确定 根据空间和非空间特征（AIM 1）以及如何招募的皮质区域以及如何 当外围听觉信号通过模拟降低而降低时，皮质的其余部分会补偿 听力障碍和人工耳蜗使用者的听众经历的光谱敏锐度（AIM 2）。 此外，我们建议采用系统级方法并研究其他皮质区域 与听觉感官区域进行交流，以协调关注和维护的关注 拥挤的声学场景（AIM 3）。我们的建议强调设计桥接的行为范例 心理声学与神经影像学研究之间的差距，从而解决了不同地区的不同地区 Cortex共同行动，以帮助我们在日常环境中进行交流。