Improving weight loss outcomes by minimizing adaptive responses to energy restriction

通过最大限度地减少对能量限制的适应性反应来改善减肥效果

• 批准号: nhmrc : 1042555
• 负责人: A/Pr Amanda Salis
• 金额: $ 41.44万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/improving-weight-loss-energy-restriction/111486
• 关键词: Improving; weight; loss; outcomes; minimizing

While losing excess weight reduces the risk of lifestyle diseases such as diabetes, current weight loss strategies are ineffective for most, in part because the body mounts a ‘famine reaction’ that increases hunger, decreases metabolic rate and may also cause loss of muscle and bone mass. This research aims to determine the effects of the famine reaction on body composition, as well as to identify new ways to block the famine reaction with food, thereby enabling more people to attain and maintain a healthy body weight and composition.

虽然减肥可以降低患糖尿病等生活方式疾病的风险，但目前的减肥策略对大多数人来说是无效的，部分原因是身体会产生“饥饿反应”，增加饥饿感，降低代谢率，还可能导致肌肉和骨质流失。这项研究旨在确定饥饿反应对身体组成的影响，并确定用食物阻断饥饿反应的新方法，从而使更多的人能够达到并保持健康的体重和组成。