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The mechansim of cachexia induced by the TGF-b superfamily cytokine, MIC-1

The mechansim of cachexia induced by the TGF-b superfamily cytokine, MIC-1
TGF-b超家族细胞因子MIC-1诱导恶病质的机制
批准号：
nhmrc : 455291
负责人：
A/Pr Amanda Salis
金额：
$36.29万
依托单位：
The University of New South Wales
依托单位国家：
澳大利亚
项目类别：
NHMRC Project Grants
财政年份：
2007
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2007-01-01 至 2009-12-31
来源：
https://researchdata.edu.au/mechansim-cachexia-induced-mic-1/94672
关键词：
mechansimcachexiainducedTGFsuperfamily

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中文摘要
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英文摘要
MIC-1 is a protein first cloned and characterised by our research group. It belongs to the TGF beta protein superfamily which is very important in development of cancer, wound - fracture healing and inflammation. Recent evidence also suggests it can act as an appetite suppressant, and this is especially relevant in conditons like cancer where it is overproduced. This project seeks to understand the mechanisms for its capacity to modify appetite
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