Green Housing Study: Boston Followup

绿色住房研究：波士顿后续行动

• 批准号: 8503423
• 负责人: Gary Adamkiewicz
• 金额: $ 18.75万
• 依托单位: HARVARD SCHOOL OF PUBLIC HEALTH
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8503423
• 关键词: Green; Housing; Study; Boston; Followup

Project Summary/Abstract Asthma currently affects nearly 22 million adults and children in the U.S., and results in direct and indirect costs exceeding $18 billion/year. (CDC, 2012, AAFA, 2012) Disparities in asthma prevalence and morbidity across economic and racial lines are striking, with prevalence rates exceeding 25% in some low-income urban areas. (Nicholas et al., 2005) The need for improvements in healthcare and for interventions which mitigate environmental exposures within these communities are significant. In order to examine the potential for "green" improvements to the home environment to reduce exposures to chemicals and other asthma triggers within the home, the Centers for Disease Control and Prevention (CDC) initiated the Green Housing Study (GHS). As stated in the RFP, the specific aims of the GHS are as follows: Specific Aim 1 To conduct an exposure assessment of chemical and biological contaminants, pesticides, volatile organic compounds (VOCs), fungi, indoor allergens (in terms of variety and concentration) in green vs. comparison housing. a. Measure interior levels of pesticides in surface wipe samples; fungi and indoor allergens in dust samples; and VOCs in air samples. b. Compare levels of biomarkers of VOCs and pesticides (in terms of variety and concentration) from the participating residents of green and comparison housing. Specific Aim 2 To examine the relationship between living in green vs. comparison housing and asthma morbidity (e.g., symptoms, emergency department visits, use of medications, lost school/work days) of children with doctor-diagnosed asthma (ages 7-12 years). Adjustments for allergic sensitization and environmental tobacco smoke (ETS) will be made. In 2011, two study sites were established: Boston and Cincinnati. Fieldwork began in the summer of 2011 and baseline assessments are being conduction currently. The requested funding will provide support for follow-up measurements of exposures and respiratory health outcomes of children who are enrolled in GHS. Our project team is a collaboration that builds upon the significant expertise and resources of colleagues from the Harvard School of Public Health (HSPH), Tufts School of Medicine, the Boston Medical Center and the University of Massachusetts, Lowell. To date, our team has developed significant expertise in all field procedures and has successfully implemented all categories of principal study activities. We propose to complete all 6- and 12-month follow-up fieldwork by June 2013.

项目摘要/摘要 哮喘目前在美国影响着近2200万成年人和儿童，并导致 直接和间接成本超过180亿美元/年。(CDC，2012，AAFA，2012) 跨越经济和种族界限的哮喘患病率和发病率令人震惊， 在一些低收入城市地区，失业率超过25%。(Nicholas等人，2005)需要 改善医疗保健和减少环境暴露的干预措施 这些社区意义重大。 为了研究“绿色”改善家居环境的潜力， 减少家中化学物质和其他哮喘诱因的暴露，美国疾病控制与预防中心 疾病控制和预防中心发起了绿色住房研究(GHS)。如中所述 《全球统一制度》的具体目标如下： 具体目标1对化学和生物污染物进行暴露评估， 杀虫剂、挥发性有机化合物(VOCs)、真菌、室内过敏原(就品种和 集中)在绿色住房与对比住房。 A.测量表面擦拭样本、真菌和室内样本中的室内杀虫剂水平 粉尘样本中的过敏原；以及空气样本中的挥发性有机化合物。 B.比较挥发性有机化合物和杀虫剂的生物标志物水平(根据种类和 集中)，来自参与的居民绿色住房和对照住房。 具体目标2检查居住在绿色住房和对比住房之间的关系 哮喘发病率(例如，症状、急诊科就诊、药物使用、丢失 被医生诊断为哮喘的儿童(7-12岁)的上学/工作日)。调整为 将制造过敏性致敏和环境烟草烟雾(ETS)。 2011年，两个研究地点相继设立：波士顿和辛辛那提。田野工作于#年开始 2011年夏季和基线评估目前正在进行中。所请求的 资金将为暴露和呼吸健康的后续测量提供支持。 参加GHS的儿童的结果。我们的项目团队是一个协作团队， 依靠哈佛公共学院的同事们的重要专业知识和资源 健康(HSPH)、塔夫茨医学院、波士顿医学中心和华盛顿大学 马萨诸塞州洛厄尔。到目前为止，我们的团队已经在所有领域开发了重要的专业知识 并成功地开展了各类主要学习活动。我们 提议在2013年6月之前完成所有为期6个月和12个月的后续实地工作。