Green Housing Study: Boston Followup

绿色住房研究：波士顿后续行动

• 批准号: 8503423
• 负责人: Gary Adamkiewicz
• 金额: $ 18.75万
• 依托单位: HARVARD SCHOOL OF PUBLIC HEALTH
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8503423
• 关键词: Green; Housing; Study; Boston; Followup

Project Summary/Abstract Asthma currently affects nearly 22 million adults and children in the U.S., and results in direct and indirect costs exceeding $18 billion/year. (CDC, 2012, AAFA, 2012) Disparities in asthma prevalence and morbidity across economic and racial lines are striking, with prevalence rates exceeding 25% in some low-income urban areas. (Nicholas et al., 2005) The need for improvements in healthcare and for interventions which mitigate environmental exposures within these communities are significant. In order to examine the potential for "green" improvements to the home environment to reduce exposures to chemicals and other asthma triggers within the home, the Centers for Disease Control and Prevention (CDC) initiated the Green Housing Study (GHS). As stated in the RFP, the specific aims of the GHS are as follows: Specific Aim 1 To conduct an exposure assessment of chemical and biological contaminants, pesticides, volatile organic compounds (VOCs), fungi, indoor allergens (in terms of variety and concentration) in green vs. comparison housing. a. Measure interior levels of pesticides in surface wipe samples; fungi and indoor allergens in dust samples; and VOCs in air samples. b. Compare levels of biomarkers of VOCs and pesticides (in terms of variety and concentration) from the participating residents of green and comparison housing. Specific Aim 2 To examine the relationship between living in green vs. comparison housing and asthma morbidity (e.g., symptoms, emergency department visits, use of medications, lost school/work days) of children with doctor-diagnosed asthma (ages 7-12 years). Adjustments for allergic sensitization and environmental tobacco smoke (ETS) will be made. In 2011, two study sites were established: Boston and Cincinnati. Fieldwork began in the summer of 2011 and baseline assessments are being conduction currently. The requested funding will provide support for follow-up measurements of exposures and respiratory health outcomes of children who are enrolled in GHS. Our project team is a collaboration that builds upon the significant expertise and resources of colleagues from the Harvard School of Public Health (HSPH), Tufts School of Medicine, the Boston Medical Center and the University of Massachusetts, Lowell. To date, our team has developed significant expertise in all field procedures and has successfully implemented all categories of principal study activities. We propose to complete all 6- and 12-month follow-up fieldwork by June 2013.

项目摘要/摘要 目前，哮喘在美国影响近2200万成人和儿童，并导致 直接和间接成本超过180亿美元/年。 （CDC，2012，AAFA，2012） 经济和种族之间的哮喘患病率和发病率令人震惊，流行率很高 在某些低收入城市地区，比率超过25％。 （Nicholas等，2005）需要 改善医疗保健和减轻环境暴露的干预措施 这些社区很重要。 为了检查家庭环境“绿色”改进的潜力 减少房屋内化学物质和其他哮喘触发因素的暴露，中心 疾病控制与预防（CDC）启动了绿色住房研究（GHS）。如所述 RFP，GHS的具体目的如下： 具体目的1以进行化学和生物污染物的暴露评估， 农药，挥发性有机化合物（VOC），真菌，室内过敏原（就多样性而言 浓度）在绿色与比较外壳中。 一个。测量表面擦除样品中农药的内部水平；真菌和室内 粉尘样品中的过敏原；和空气样品中的VOC。 b。比较VOC和农药的生物标志物的水平（就多样性而言 集中度）来自绿色和比较住房的参与居民。 具体目标2以检查生活中的生活与比较住房与比较之间的关系 哮喘发病率（例如，症状，急诊室就诊，使用药物，丢失 患有医生诊断哮喘的儿童的学校/工作日（7-12岁）。调整 将进行过敏反应和环境烟草烟雾（ETS）。 2011年，建立了两个研究地点：波士顿和辛辛那提。现场工作开始了 目前正在进行2011年夏季和基线评估。请求 资金将为接触和呼吸健康的后续测量提供支持 加入GHS的儿童的结果。我们的项目团队是建立的合作 在哈佛公立学院的同事的大量专业知识和资源之后 健康（HSPH），塔夫茨医学院，波士顿医学中心和大学 马萨诸塞州，洛厄尔。迄今为止，我们的团队在所有领域都发展了重要的专业知识 程序并已成功实施了所有主要研究活动。我们 建议在2013年6月之前完成所有6个月和12个月的后续野外工作。