Integrated Physiology Training: Molecule to Organism

描述（由申请人提供）：在过去的二十年中，全国各地的生理学部门的培训经历了一种转变，这种转变使学生无法从整个动物到细胞和分子水平的学科广度上进行透彻的理解。威斯康星医学院（MCW）的生理学系是一个例外，它提供研究培训，强调所有这些层面的知识的整合，并培养对这些知识与疾病过程之间关系的认识。根据目前的建议，我们将继续每年为六名nih支持的学员提供细胞、分子和全动物生理学方面的特殊培训。拟议的培训的一个独特方面是指导计划，其中包括来自各种传统领域的基础科学家以及临床科学家。研究生将在全国范围内招募，并将根据本科学历、以前的研究经验和对研究事业的承诺进行选择。学生必须完成研究生院的第一年，他们才会被考虑为NIH培训支持。学员的选择将主要基于在研究生院第一年的课程作业和研究实验室的表现。学员为MCW生物医学研究生院全日制博士研究生。学员将完成必修课和选修课，并完成一项研究项目，包括使用分子生物学技术、分离组织、全动物或临床研究。主要目标是为学员提供跨学科基础科学和转化研究的广泛基础。学员将培养批判性思维、综合推理和技术技能，以创建和参与与预防和控制高血压、中风和呼吸系统疾病相关的不断发展的研究事业。培训的一个创新特点是强调解决国家在后基因组时代为生物医学研究的综合系统未来培训的需要。研究训练由生理学教师直接指导，其他基础科学和临床科室的共同导师指导。受训者及其导师将通过与项目主任和研究生委员会的一系列正式和非正式会议，对进展进行持续评估。（摘要结束）

DESCRIPTION (provided by applicant): Over the last twenty years, training in Physiology departments throughout the country has undergone a transformation that precludes students from a thorough understanding that spans the breadth of the discipline from the whole animal to the cellular and molecular level. An exception is the Physiology Department of the Medical College of Wisconsin (MCW), that offers research training emphasizing integration of knowledge at all of these levels with development of an appreciation for the relationship of this knowledge to disease processes. With the current proposal, we will continue providing this exceptional training in cellular, molecular, and whole animal Physiology for six NIH-supported trainees each year. A unique aspect of the proposed training is the mentoring program, which includes basic scientists from a variety of traditional areas as well as clinician scientists. Graduate students wll be recruited nationally and will be selected on the basis of undergraduate academic credentials, previous research experience, and commitment to a career in research. Students must complete the first year of graduate school before they will be considered for NIH training support. Selection of trainees will be based primarily on performance in course work and in the research laboratory during the first year of graduate school. Trainees are full-time Ph.D. candidates in the MCW Graduate School of Biomedical Sciences. Trainees will complete required and elective courses and a research project that includes use of the techniques of molecular biology, isolated tissues, and whole animal or clinical investigation. The major objective is to provide trainees with a broad foundation in interdisciplinary basic science and translational research. The trainee will develop the critical thinking, integrative reasoning, and technical skills required to create and participate in evolving research careers related to prevention and control of hypertension, stroke, and respiratory diseases. An innovative feature of the training is the emphasis on addressing the national need to train for the integrated-systems future of biomedical research in the post- genome era. Research training is under the direct supervision of Physiology faculty along with co-mentors from other basic science and clinical departments. Trainees and their mentors will undergo continuous evaluation of progress through a series of formal and informal meetings with the program director and the graduate committee. (End of Abstract)