Annual American Society for Rickettsiology (ASR) Workshop

描述（由申请人提供）：美国立克次体病学会（ASR）成员的国际研究人员来自从澳大利亚到津巴布韦的国家，当然也包括美国和欧洲。媒介传播的立克次体病原体在全球的出现助长了这种广泛的地理代表性。ASR的年会甚至在出版物发表之前就促进了科学发现和资源的交流。这导致了合作成员之间的相互交织，这非常有利于该领域本身的进步，并促进了年轻研究人员与知名科学家之间的联系。在每次会议上，组织者都会从每个参加会议的实验室中赞助一名年轻成员（主要是学生、博士后研究人员和助理教授），特别为了加强新信息的流动，并鼓励年轻的立克次病学家留在这个领域。在去年的会议结束时，组织者邀请所有与会者进行讨论，以确定被认为是推动佝偻病学进步的最优先的研究领域。因此，我们建议在年度ASR会议框架内组织一个为期1天半的研讨会，讨论“立克次体基因表达的调控”的中心主题。这将广泛包括节肢动物载体（Abdu Azad UMD, Kevin Macaluso LSU）和哺乳动物宿主（Jere McBride UTMB, Matt Welch UCB, Yasuko Rikihisa OSU）成功定定的分子决定因素，节肢动物（Joao Pedra UCR, Viveka Vadyvaloo WSU）和哺乳动物（Guy Palmer WSU, Nahed Ismail UPMC）的防御反应，以及病原体的遗传操作以确定协调这种相互作用的调节机制(Ulrike Munderloh UMN, Dan Rockey OR，丹尼尔·沃斯AR)。研讨会将包括主要演讲者的口头报告，以及由每位主要演讲者从初级教师，博士后科学家和提交摘要的学生中选择的额外演讲者。口头报告之后将有一个深入的讨论环节。口头报告环节辅以符合中心主题的海报环节。将积极招募代表性不足群体的成员担任演讲者和海报展示者。主要演讲者将被要求将海报组织成五至六人一组的小组，并将在海报展示者和与会与会者之间领导他们的讨论。在会议主席的帮助下，并与演讲者合作，将总结口头和海报演讲的主要影响，包括讨论，并在会议结束后出版。

DESCRIPTION (provided by applicant): The international community of researchers who are members of the American Society for Rickettsiology (ASR) is represented in countries from Australia to Zimbabwe, including, of course, the USA and Europe. This wide geographic representation is fed by the global emergence of vector-borne rickettsial pathogens. The annual meetings of the ASR foster scientific exchange of discoveries and resources even before publication. This has resulted in an interwoven fabric of cooperating members that is highly conducive to the advancement of the field itself and facilitates connections between young investigators with established scientists. At every meeting, the organizers sponsor a junior member (primarily students, postdoctoral researchers and assistant professors) from each attending laboratory, specifically with the aim to strengthen the flow of new information, and to encourage young rickettsiologists to remain in the field. At the end of last year's meeting the organizers invited a discussion among all attendees to identify research areas viewed to be of highest priority for driving advances in rickettsiology. As a result, we propose to organize a 1 and 1/2-day workshop within the framework of the annual ASR meeting that addresses the central theme of "Regulation of Gene Expression in Rickettsiae." This will broadly include molecular determinants of successful colonization of the arthropod vector (Abdu Azad UMD, Kevin Macaluso LSU) and the mammalian host (Jere McBride UTMB, Matt Welch UCB, Yasuko Rikihisa OSU), defensive responses of arthropods (Joao Pedra UCR, Viveka Vadyvaloo WSU) and mammals (Guy Palmer WSU, Nahed Ismail UPMC), and genetic manipulation of pathogens to identify the regulatory mechanisms that coordinate this interplay (Ulrike Munderloh UMN, Dan Rockey OR, Daniel Voth AR). The workshop will comprise oral presentations by the key speakers, and additional speakers who will be selected by each key speaker from junior faculty, postdoctoral scientists and students who have submitted abstracts. An in-depth discussion session will follow oral presentations. Oral presentation sessions are complemented by poster sessions that fall within the central theme. Members from underrepresented groups will be actively recruited as speakers and poster presenters. Key speakers will be asked to organize posters into groups of about five - six each, and will lead their discussion among poster presenters and participating meeting attendees. With the help of session chairs, and in collaboration with presenters, the major impacts of oral and poster presentations will be summarized, including the discussions, and published following the meeting.