Breast Oncology

乳腺肿瘤学计划（计划）由来自13个不同UCSF部门的39名计划成员组成。该计划支持和促进乳腺癌的基础，临床和人口研究，并促进这些研究结果转化为改善癌症管理和控制。该方案的主题如下：（1）流行病学和病因学;（2）癌症预防、风险模型和早期发现;（3）癌症进展的遗传学和生物学;（4）新的治疗靶点和方法;（5）外展、临床护理提供和结果。该计划中的研究得到了湾区乳腺癌SPORE的支持，该计划是八个大型多学科，多机构项目，支持一个或多个主题的工作，加州总统办公室的多校区大学赞助的ATHENA乳腺健康网络整合了临床护理和研究，由众多个人赞助商发起的赠款。 自上一次竞争性更新以来，许多工作都致力于研究者发起的治疗试验，创新的伴随诊断临床试验，测试新的放射肿瘤治疗提供系统，包括相关科学，以及建立符合CLIA的测试实验室和综合生物信息学和IT基础设施。该计划变得更加有凝聚力，具有高水平的互动，从而与联合计划和项目领导者以及跨学科的联合研究者获得了新的赠款资金。在几个讨论论坛中鼓励计划成员之间的互动，包括每周一次的多学科研讨会，年度务虚会，每周一次的肿瘤委员会，每两周一次的乳腺研究现场审查会议，每月一次的社区论坛和患者-医生管理讨论系列。在上一个预算年度，该方案经同行审查的支助总额为22 189 900美元。该方案有17%的方案内和17%的方案间出版物。

The Breast Oncology Program (Program) is comprised of 39 Program Members from 13 different UCSF departments. The Program supports and stimulates basic, clinical, and population research in breast cancer and facilitates the translation of these findings into improved cancer management and control. The Program's themes are as follows: (1) epidemiology and etiology; (2) cancer prevention, risk models, and early detection; (3) genetics and biology of cancer progression; (4) new therapeutic targets and approaches; and (5) outreach, clinical care delivery, and outcomes. Research in the Program is supported by the Bay Area Breast Cancer SPORE, eight large multi-disciplinary, multi-institutional projects that support work in one or more themes, a multi-campus University of California Office of the President sponsored ATHENA Breast Health Network integrating clinical care and research by numerous individual investigator-initiated grants. Since the last competitive renewal much effort has been dedicated towards investigator initiated therapeutic trials, innovative companion diagnostic clinical trials, testing new radiation oncology treatment delivery systems including correlative science, as well as establishing a CLIA-compliant testing laboratory and an integrative bioinformatics and IT infrastructure. The Program has become more cohesive, has a high level of interaction that has led to new grant funding with joint program and project leaders and co-investigators across disciplines. Interactions between Program members are encouraged in several discussion forums, including a weekly multidisciplinary seminar, an annual retreat, a weekly tumor board, a bi-weekly breast site study review meeting, a monthly community forum, and a patient-physician management discussion series. The Program has $22,189,900 total peer-reviewed support for the last budget year. The Program has 17% intra-programmatic and 17% inter-programmatic publications.